These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Not reported 2004-004736-30 Peginterferon alfa-2a and Ribavirin Combination Therapy in Patients with HBeAg-negative Chronic HBV Infection 2009-10-15 due-trials
Ongoing 2006-000701-35 Chemoreflex sensitivity during exercise with beta blockers not-yet-due
Ongoing 2006-002098-30 Efficacy of Inhaled RhDNase in Mechanically Ventilated Pediatric Patients with an Atelectasis not-yet-due
Ongoing 2006-002337-20 Efficacy of peripherally targeted inhaled rhDNase for persistent obstructive asthma in childhood not-yet-due
Ongoing 2006-004080-55 Stepwise Medical Treatment of Cushing’s Disease: a prospective open label multi-center trial with SOM230 mono- and combination therapy with dopamine agonists and ketoconazole not-yet-due
Ongoing 2006-004709-24 Mycophenolate sodium (Myfortic®) in the Treatment of Uveitis: a Pilot Study. not-yet-due
Ongoing 2006-004811-22 A prospective, randomized, double-blind comparison of 5 % against 1 % povidone-iodine solution in preoperative antisepsis for strabismus surgery in young children. not-yet-due
Ongoing 2006-005772-41 LIMIT: Lowering the Incidence of vascular complications with Metformin in patients with Impaired glucose tolerance and a recent TIA or minor ischemic stroke: a phase 2, randomized, controlled trial not-yet-due
Exempt 2006-006804-12 Levetiracetam (Keppra®) in neonates not-yet-due
Ongoing 2006-007091-15 Glivec (imatinib mesylate) in systemic sclerosis, a pilot study not-yet-due
Ongoing 2007-000467-23 Maternal and fetal haemodynamic response to Nifedipine tocolysis in normotensive pregnant women. not-yet-due
Ongoing 2007-000727-17 Maternal, uteroplacental and fetal haemodynamic effect of Nicardipine in severe pre-eclampsia. not-yet-due
Ongoing 2007-000935-25 ‘Peripheral targeting of inhaled rhDNase in stable CF patients.’ not-yet-due
Ongoing 2007-001170-92 Dexamethasone for postoperative pain relief following tonsillectomy in children not-yet-due
Ongoing 2007-002763-27 A multi-center, randomized, controlled trial with programmed introduction of Sirolimus-based, Calcineurin inhibitor free immunosuppression in recipients of non-heart-beating donor kidney grafts. not-yet-due
Ongoing 2007-003377-15 Chemoreflex sensitivity, exercise and beta agonists not-yet-due
Ongoing 2007-003537-16 Estetrol Therapy in Sjogren's Syndrome: An Open Proof of Concept Study not-yet-due
Ongoing 2007-005232-81 Wet-wrap treatment in children with atopic eczema using the wet-wrap method with diluted corticosteroids versus emollients not-yet-due
Ongoing 2007-005619-24 Morphine intravenous vs. Acetaminophen intravenous in neonates and young infants undergoing major non-cardiac surgery. not-yet-due
Completed, but no date 2008-000053-35 A phase II study to assess engraftment and engraftment kinetics after double cord blood transplantation with a reduced-intensity conditioning regimen in patients eligible for allogeneic stem cell tran... bad-data
Ongoing 2008-000069-41 Regulation of colloid osmotic pressure during cardiopulmonary bypass in infants: prospective randomised trial not-yet-due
Completed, but no date 2008-000424-86 Development and introduction of a pediatric liquid formulation of 6-mercaptopurine for treatment of leukemia bad-data
Ongoing 2008-000793-20 Sirolimus (Rapamune®) for the treatment of anti-Hu associated paraneoplastic neurological syndromes not-yet-due
Ongoing 2008-001183-37 PROSPECTIVE RANDOMIZED COMPARISON OF EMR VERSUS EMR FOLLOWED BY PHOTODYNAMIC THERAPY FOR THE TREATMENT OF EARLY BARRETT’S CANCER not-yet-due
Ongoing 2008-001827-76 The role of TSH in the human immune system, a clinical trial not-yet-due
Ongoing 2008-004114-28 Effectiveness of Diclofenac versus Paracetamol in primary care patients with knee osteoarthritis. not-yet-due
Ongoing 2008-004830-26 Optimization of electroconvulsive therapy (ECT) and continuation pharmacotherapy in major depressive disorder not-yet-due
Ongoing 2008-005619-16 Impact of anti-tumor necrosis factors antibodies treatment on fertility of inflammatory bowel diseases male patients not-yet-due
Ongoing 2008-005659-83 Second IVIg Dose in GBS patients with poor prognosis (SID-GBS trial) not-yet-due
Ongoing 2008-005814-28 Cost-effectiveness of viscosupplementation therapy for patients with osteoarthritis of the knee: a randomized clinical trial not-yet-due
Ongoing 2008-006889-29 A pilotstudy comparing systemic versus locoregional injection of radiolabelled somatostatin analogues in patients with neuroendocrine Gastro-Entero_Pancreatic (GEP) tumors. not-yet-due
Completed, but no date 2008-007446-54 LOWERING VIRAL LOAD WITH NUCLEOS(T)IDE ANALOGUES PRIOR TO PEG-INTERFERON ALFA-2B TREATMENT TO INCREASE SUSTAINED RESPONSE IN HBEAG-POSITIVE CHRONIC HEPATITIS B (PADD-STUDY) bad-data
Ongoing 2008-008251-42 Clinical and immunological effects of imiquimod and HPV-vaccination compared to imiquimod alone in female patients with Usual type VIN not-yet-due
Ongoing 2008-008293-31 Early introduction in the Netherlands of alglucosidase alfa manufactured in a 4000 liter bioreactor not-yet-due
Exempt, with results 2009-009457-13 A Phase I/II study of clofarabine in combination with cytarabine and liposomal daunorubicin in children with relapsed/refractory pediatric AML 2015-03-09 not-yet-due
Completed, but no date 2009-010965-22 The effect of long-term simvastatin treatment on cognitive function and daily life in children with Neurofibromatosis 1: a one year randomized controlled trial bad-data
Completed, but no date Terminated 2009-010999-19 Protein and Energy Interactions in Critically Ill Children bad-data
Ongoing 2009-011158-17 Additional treatment to primary PCI: effects of ischemic postconditioning and Exenatide. not-yet-due
Completed, but no date 2009-011827-30 Cost-effectiveness of subcutaneous immunotherapy in adults with allergic rhinitis. bad-data
Ongoing 2009-012186-63 Landelijke Werkgroep voor Neuro-Oncologie trial (LWNO 0901) Randomized phase II study of Bevacizumab versus Bevacizumab plus Lomustine in patients with recurrent Glioblastoma: the BELOB trial not-yet-due
Ongoing 2009-013022-16 Effecten en bijwerkingen van opioïden: een studie naar de rol van farmacokinetische en farmacogenetische heterogeniteit. not-yet-due
Listed as ongoing, but also has a completion date and reported results 2009-014037-25 Bortezomib (Velcade®): a feasibility and phase II study in childhood relapsed acute lymphoblastic leukemia 2015-10-21 bad-data
Completed, but no date Terminated 2009-014268-20 VZV vaccination to prevent herpes zoster after transplantation bad-data
Ongoing 2009-014892-31 Morphine intravenous vs. Paracetamol intravenous in children on ECMO not-yet-due
Ongoing 2009-014922-40 Carfilzomib in combination with Thalidomide and Dexamethasone for remission induction and consolidation of Multiple Myeloma at first presentation not-yet-due
Ongoing 2009-017315-15 Multi Center Clinical trial of endovascular treatment of acute ischemic stroke in the Netherlands. not-yet-due
Ongoing 2010-018498-39 VItamin D treatment Effect on retinal nerve fiber loss after Optic neuritis not-yet-due
Ongoing 2010-018917-30 A SINGLE-CENTER PHARMACOGENETIC STUDY OF DONOR AND RECIPIENT TO IMPROVE THE EFFICACY AND REDUCE THE NEPHROTOXICITY OF TACROLIMUS AFTER KIDNEY TRANSPLANTATION not-yet-due
Ongoing 2010-019019-39 'Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) as an outcome measure to evaluate the effectiveness of intra-articular hyaluronic acid for knee osteoarthritis’ not-yet-due
Ongoing 2010-019398-14 IMPROVEMENT OF RENAL FUNCTION BY CONVERSION OF TACROLIMUS TO EVEROLIMUS 3 MONTHS AFTER KIDNEY TRANSPLANTATION not-yet-due
Ongoing 2010-019519-39 Efficacy of RAD001/everolimus in Autism and NeuroPsychological deficits in children with TSC (RAPIT-trial) not-yet-due
Exempt 2010-019897-33 Selective D1 activation by addition of L-Dopa to antipsychotic treatment in patients with schizophrenia not-yet-due
Ongoing 2010-020303-69 Enzyme substitution in exocrine pancreatic insufficiency; Self administration against a fixed dose regimen. not-yet-due
Completed, but no date 2010-020332-19 Putting Resistance under the Microscope. (Weerstand onder de Loep) bad-data
Ongoing 2010-021437-30 Paracetamol (Acetaminophen) in Stroke 2 (PAIS 2): A randomized, placebo-controlled clinical trial of high-dose paracetamol in patients with acute stroke and a body temperature of 36.5°C or above not-yet-due
Ongoing 2010-021844-17 Perioperative esmolol infusion for haemodynamic stability during major vascular surgery. not-yet-due
Listed as ongoing, but also has a completion date 2010-022235-10 A Phase I/II study of Azacitidine (Vidaza®) in pediatric patients with newly diagnosed or relapsed high-grade pediatric MDS or JMML 2020-02-12 bad-data
Ongoing 2010-022655-29 Randomised open label cross-over study into the efficacy of RApamycin in children with Tuberous sclerosis complex with intractable Epilepsy (RATE-trial) not-yet-due
Ongoing 2010-023946-58 Immunogenicity and safety of an adjuvant hepatitis B vaccine (fendrix) compared to Engerix in non-responding HIV-infected patients not-yet-due
Ongoing 2011-000213-39 Intramuscular corticosteroid injections in hip osteoarthritis: a double-blinded randomized controlled trial not-yet-due
Ongoing 2011-002128-41 Accumulation of Nadroparin Used in Renal Insufficiency Assessed by anti-Xa levels not-yet-due
Completed, but no date Terminated 2011-002287-24 Massive blood loss in children during multiple trauma or major surgery: bad-data
Ongoing 2011-003134-13 5-Aminolevulinic Acid PhotoDynamic Therapy for the treatment of premalignant disorders of the vulva. not-yet-due
Ongoing 2011-003264-77 A prospective trial with ketoconazole and octreotide combination therapy for treatment of Cushing’s disease. not-yet-due
Completed, but no date, and reported results 2011-003346-40 A phase II study in mCRPC on the pharmacodynamic effects of budesonide on cabazitaxel (Jevtana®): A randomised, open-label multicenter study: CABARESC bad-data
Not reported 2011-003815-46 Double blind placebo controlled randomized intervention study aiming at reducing dexamethasone related side effects in children with acute lymphoblastic leukemia (ALL). 2015-03-30 due-trials
Ongoing 2011-004201-25 The BOKITO-1B Study: not-yet-due
Ongoing 2011-004231-31 Randomized double blind multi-centre study of the effects on low-dose pegvisomant treatment in acromegalic subjects in whom the IGF1 levels has been normalized by long-acting somatostatin analogues not-yet-due
Ongoing 2011-004272-11 The BOKITO-2B Study: Tenofovir DF Bone and Kidney Toxicity. not-yet-due
Ongoing 2011-004995-13 Endovascular renal sympathetic denervation versus spironolactone for treatment-resistant hypertension: a randomized, multicentric study not-yet-due
Ongoing 2011-005256-34 Sumatriptan non-responders: evaluation of a possible biomarker not-yet-due
Exempt Terminated 2011-005497-28 Pediatric Microdosing: elucidating age-related changes in oral absorption 2017-12-31 not-yet-due
Ongoing 2011-006237-42 Optimization of exercise therapy in type 2 diabetes mellitus not-yet-due
Ongoing 2012-000645-13 Infliximab Top-down Study in Kids with Crohn’s disease not-yet-due
Ongoing 2012-001142-18 Efficacy and pharmacokinetics of a switch from a regimen consisting of emtricitabine, nevirapine and tenofovir to rilpivirine, emtricitabine and tenofovir in virologically suppressed HIV-1 infected pa... not-yet-due
Ongoing 2012-001416-27 Treatment of Cancer in the head and Neck: The Role of Hyperbaric Oxygen in Reducing Swallowing Problems not-yet-due
Ongoing 2012-001591-11 Symptomatic treatment of pollen related allergic rhinoconjunctivitis and the relation with asthma with children in the General practice not-yet-due
Ongoing 2012-002230-37 “Novel Approach to Detect the Detailed Effects of Vildagliptin on Beta-cell not-yet-due
Ongoing 2012-002503-17 Tobramycin nebulisation with I-neb (TONI) study in children with cystic fibrosis: pharmacokinetics and safety not-yet-due
Ongoing 2012-003169-16 Immune monitoring to characterize T-cell responses of kidney transplant patients during co-stimulation blockade by belatacept not-yet-due
Ongoing 2012-003680-21 Putting Resistance under the Microscope II. ; A Randomized Controlled Trial on the effects of midazolam on the quality of postoperative recovery in patients not-yet-due
Ongoing 2012-004065-41 Comparative study of pharmacokinetics of amlodipine besilate oral liquid and tablets in healthy Dutch volunteers not-yet-due
Ongoing 2012-005150-34 Dose response trial of IV immunoglobulin in chronic inflammatory demyelinating polyradiculoneuropathy not-yet-due
Listed as ongoing, but also has a completion date 2012-005226-29 Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease 2015-08-31 bad-data
Ongoing 2012-005330-10 Maternal pharmacokinetics and pharmacodynamics of nicardipine (iv) during treatment of severe hypertension in pregnancy. not-yet-due
Reported results 2012-005395-34 Prospective evaluation of the predictive value of a circulating tumor cell (CTC) sensitivity profile to Cisplatin chemotherapy in metastatic breast cancer patients 2019-02-28 due-trials
Ongoing 2012-005640-14 The effects of hormonal contraception on the HPA-axis functioning not-yet-due
Completed, report not yet due Terminated 2013-000909-24 "OPTI-CLOT": 2020-04-16 not-yet-due
Ongoing 2013-000956-16 Effect of low-dose ketamine on postoperative delirium in patients undergoing noncardiac surgery: a pilot study. not-yet-due
Ongoing 2013-001525-10 Studying the metabolism of sorafenib (Nexavar®) by OATP1B blockage in adult cancer patients not-yet-due
Ongoing 2013-002026-22 Rectal and oral omeprazole treatment of gastroesophageal reflux in infants with esophageal atresia or congenital diaphragmatic hernia. not-yet-due
Ongoing 2013-002122-23 The influence of electroencephalographic Narcotrend Index™- guidance of of propofol administration on recovery from procedural sedation for gastrointestinal endoscopy in paediatric patients not-yet-due
Ongoing 2013-002189-38 OPTIMIZING PERIPHERAL CIRCULATION WITH VASODILATOR THERAPY IN CRITICALLY ILL PATIENTS WITH CIRCULATORY SHOCK: A PILOT STUDY not-yet-due
Completed, but no date, and reported results Terminated 2013-002744-89 Bioavailability of oral ciprofloxacin tablets and suspension in pediatric cancer patients bad-data
Ongoing 2013-003405-26 The effect of Lamotrigine on cognitive deficits associated with Neurofibromatosis type 1: a phase II randomized controlled multi-centre trial (NF1-EXCEL) not-yet-due
Ongoing 2013-003603-19 Influence of an acidic beverage on the absorption of erlotinib not-yet-due
Ongoing 2013-003679-36 Postoperative Ileus reduction by NicOtine gum CHewIng after Operation: a pilot cohort study not-yet-due
Completed, but no date Terminated 2013-003842-18 Prevention of renal and bladder damage in children with spina bifida by means of early injections with Botulinum-Toxin-A (Botox): a pilot study. bad-data
Ongoing 2013-004952-39 Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases not-yet-due
Completed, but no date 2013-004988-32 Rotterdam Observational Study in CIDP of Pharmacokinetics of Intravenous γ-globulin bad-data
Ongoing 2013-005323-17 Pharmacokinetic and pharmacodynamic properties of amlodipine oral solution in the pediatric population not-yet-due
Completed, but no date Terminated 2013-005376-17 Sandostatin therapy in sarcoidosis bad-data
Ongoing 2013-005479-42 Pilot study: Toxicity of oestradiol for adjuvant endocrine therapy in locally confined prostate cancer not-yet-due
Ongoing 2013-005572-17 Optimizing propofol dosing for (preterm) newborn infants that need not-yet-due
Listed as ongoing, but also has a completion date 2014-000178-20 Thyroid hormone analog therapy of patients with severe psychomotor retardation caused by mutations in the MCT8 thyroid hormone transporter: The Triac Trial. 2017-07-28 bad-data
Completed, report not yet due 2014-000675-13 Natalizumab (Tysabri®) for the treatment of anti-Hu associated paraneoplastic neurological syndromes 2020-11-25 not-yet-due
Ongoing 2014-000681-22 EFFECT OF ISO-OSMOLAR CONTRAST MEDIUM ON CORONARY OPACIFICATION AND HEART RHYTHM IN CORONARY CT ANGIOGRAPHY (ISO-COR) not-yet-due
Ongoing 2014-001372-66 Tacrolimus monotherapy in immunologically low-risk kidney transplant recipients: a pilot randomized-controlled study. not-yet-due
Ongoing 2014-001406-17 Ventilator Associated Pneumonia: addition of Tobramycin Inhalation antibiotic treatment to standard IV antibiotic treatment not-yet-due
Reported results 2014-001587-35 Dexmedetomidine in awake implantation of neuromodulative systems. 2014-02-16 due-trials
Ongoing 2014-001919-39 Lengthening Adalimumab Dosing Interval in IBD patients in long term not-yet-due
Ongoing 2014-002219-41 A prospective single-centre double blind randomized study on the efficacy and safety of 4 weekly pasireotide LAR administration in combination with or without weekly pegvisomant in previously controll... not-yet-due
Ongoing 2014-002444-40 A Phase II study of Selinexor (KPT-330) combined with bortezomib and dexamethasone (SVd) for induction and consolidation for patients with progressive or refractory Multiple Myeloma. not-yet-due
Exempt Terminated 2014-003269-46 Pediatric microdosing midazolam: elucidating age-related changes in oral drug absorption not-yet-due
Completed, but no date Terminated 2014-003834-21 Effectiveness of penfluridol (oral long acting neuroleptic) as compared to second generation oral neuroleptics in psychotic disorder patients: an open label randomized controlled trial. bad-data
Ongoing 2014-004189-64 Hunting for the off-target properties of ticagrelor on endothelial function and other circulating biomarkers in humans not-yet-due
Ongoing 2014-004432-18 Activity of trastuzumab based chemotherapy in metastatic breast patients with HER2-negative primary tumor but HER2 positive circulating tumor cells (CareMore-Trastuzumab) not-yet-due
Completed, but no date Terminated 2014-005454-19 The Dolutegravir Antiretroviral Mono-Therapy for HIV Trial bad-data
Ongoing 2014-005702-37 Top-Down Infliximab Study in Kids with Crohn's disease (TISKids) not-yet-due
Completed, but no date, and reported results 2015-000964-33 Dexmedetomidine versus propofol in awake implantation of a neuromodulative system. bad-data
Ongoing 2015-001043-37 Pharmacokinetics of Lorazepam Oral Liquid in Paediatric ICU Patients not-yet-due
Completed, but no date Terminated 2015-001669-16 Duloxetine for chronic osteoarthritis pain; an important alternative? bad-data
Ongoing 2015-001835-20 Morphine intravenous vs. paracetamol intravenous after cardiac surgery in neonates and infants. not-yet-due
Ongoing 2015-002209-12 Less opioids after major abdominal surgery in young infants using wound catheter infusion with local anesthetics: a randomized controlled trial. not-yet-due
Completed, report not yet due Terminated 2015-002820-20 Are alpha blockers effective in the treatment of bladder elimination problems in female patients with Multiple Sclerosis? 2020-04-07 not-yet-due
Other 2015-002916-34 A phase I/II study of Bosutinib in pediatric patients with Chronic Myeloid Leukemia who are resistant or intolerant to at least one prior Tyrosine Kinase Inhibitor therapy, ITCC-054/AAML1621 not-yet-due
Ongoing 2015-003210-24 Grazoprevir (MK-5172) + Elbasvir (MK-8742) for the treatment of acute not-yet-due
Ongoing 2015-003551-22 STATIC IV: Efficacy of a loading dose of intravenous salbutamol in patients admitted to a PICU for severe acute asthma not-yet-due
Other 2015-004143-39 A Phase 3 randomised, double-blind, controlled trial of inhaled 7% hypertonic saline versus 0.9% isotonic saline for 48 weeks in patients with Cystic Fibrosis at 3-6 years of age in parallel with the ... not-yet-due
Ongoing 2015-004604-37 Aspirin provocation of patients with Systemic Mastocytosis not-yet-due
Ongoing 2015-005045-31 Switching to Tenofovir Alafenamide Fumarate or ABACavir in patients with Tenofovir Disoproxil Fumarate associated eGFR decline. A randomized clinical trial. not-yet-due
Exempt 2015-005437-53 A phase 1B of crizotinib either in combination or as single agent in pediatric patients with ALK, ROS1 or MET positive malignancies Study ITCC 053 not-yet-due
Ongoing 2015-005559-29 Within-patient variability in tacrolimus pharmacokinetics in renal transplant patients treated with different tacrolimus formulations. not-yet-due
Ongoing 2015-005700-28 An evaluation of the effectivity of the current treatment of uncomplicated urinary tract infections with fosfomycin. not-yet-due
Completed, but no date 2015-005784-17 The effects of the proton pump inhibitor esomeprazole on the bioavailability of regorafenib in patients with a metastatic colorectal cancer (mCRC) or gastrointestinal stromal tumour (GIST). bad-data
Other 2016-000227-71 A phase I/II study of Inotuzumab Ozogamicin as a single agent and in combination with chemotherapy for pediatric CD22-positive relapsed/refractory Acute Lymphoblastic Leukemia not-yet-due
Ongoing 2016-000279-26 Trigeminovascular effects of propranolol in migraine treatment not-yet-due
Ongoing 2016-000318-31 Ledipasvir and sofosbuvir for 8 weeks for the treatment of chronic hepatitis C genotype 4 in patients without cirrhosis. HepNed-001 study not-yet-due
Ongoing 2016-000406-11 The influence of electroencephalographic Narcotrend Index™ - guidance of propofol administration on recovery from procedural sedation for gastrointestinal endoscopy in children between 1 and 12 years not-yet-due
Completed, but no date Terminated 2016-000686-23 The Rotterdam Antiplatelet Therapy in Vascular Patients Study bad-data
Ongoing 2016-000859-27 Efficacy and mode of action of apremilast (Otezla) in moderate hidradenitis suppurativa. not-yet-due
Completed, but no date 2016-001269-10 A pharmacokinetic study of Docetaxel and Prednisone in men with metastatic castration-resistant or hormone-sensitive prostate cancer. bad-data
Not reported 2016-001597-15 Influence of a fatty beverage (Milk) on the absorption of erlotinib: a randomized, cross-over pharmacokinetic study (MERLOT-study) 2019-12-27 due-trials
Ongoing 2016-001663-36 Cost-effectiveness of adalimumab with adjuvant surgery versus adalimumab monotherapy in the treatment of hidradenitis suppurativa. not-yet-due
Ongoing 2016-001875-57 Desmopressin and FVIII concentrate combination treatment in non-severe hemophilia A patients undergoing minor interventions not-yet-due
Ongoing 2016-002287-14 Death rattle in the dying phase: is prophylactic treatment useful? not-yet-due
Ongoing 2016-002383-13 Umbilical cord blood transplantation in high-risk hematological patients using stemregenin-1 expanded hematopoietic stem cells. not-yet-due
Listed as ongoing, but also has a completion date and reported results 2016-002724-83 A phase IIa randomized, placebo controlled, double blinded study to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral ther... 2017-11-02 bad-data
Ongoing 2016-002859-19 Withdrawing off-label antipsychotics in people with intellectual disabilities: why does it fail? not-yet-due
Ongoing 2016-002993-11 A single arm phase 2 multicenter study determining the response to Cabazitaxel in metastatic prostate cancer (mCRPC) patients with AR-V7 positive circulating tumor cells (CTCs) not-yet-due
Ongoing 2016-003428-21 Non-inferiority multicentre randomized controlled trial comparing short versus standard course postoperative antibiotic treatment for complex acute appendicitis not-yet-due
Completed, but no date 2016-004008-71 The effect of curcumin and piperine on the pharmacokinetics of tamoxifen in patients with estrogen receptor positive breast cancer ‘the ELDORADO study’ bad-data
Ongoing 2016-004299-24 Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk score - a feasibility study not-yet-due
Other 2017-000421-13 Newborns with Congenital Diaphragmatic hernia: inhaled Nitric Oxide versus intravenous Sildenafil: an international randomized controlled trial not-yet-due
Ongoing 2017-000949-53 REduce BlAdder CAncer REcurrence in patients treated for upper urinary tract urothelial carcinoma (REBACARE Trial) not-yet-due
Ongoing 2017-000976-27 Biomarker discovery study to identify patients with advanced urothelial cancer benefitting from pembrolizumab treatment not-yet-due
Ongoing 2017-001284-20 The effects of the proton pump inhibitor esomeprazole on the bioavailability of afatinib (Giotrif®) in patients with non-small cell lung cancer (NSCLC) 'the BIO-GIO study' not-yet-due
Ongoing 2017-001466-21 Multicenter Randomized CLinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands. The effect of periprocedural MEDication: heparin, antiplatelet agents, both or neither. not-yet-due
Ongoing 2017-001525-40 Effectiveness of different strengths of topical steroids: providing evidence for a better treatment strategy in children with atopic dermatitis in general practice. not-yet-due
Ongoing 2017-001665-25 Formoterol-beclomethasone in patients with bronchiectasis: a randomized, double-blind, placebo-controlled trial (Forza study) not-yet-due
Completed, but no date Terminated 2017-001681-24 Avoiding tacrolimus under- and overexposure by using a new dosing algorithm for pediatric renal transplant recipients bad-data
Ongoing 2017-002036-17 THE (COST)EFFECTIVENESS OF NEOADJUVANT FOLFIRINOX VERSUS NEOADJUVANT GEMCITABINE BASED CHEMORADIOTHERAPY AND ADJUVANT GEMCITABINE FOR (BORDERLINE) RESECTABLE PANCREATIC CANCER not-yet-due
Ongoing 2017-002470-40 Observational study of the effects of probenecid on the pharmacokinetics and pharmacodynamics of sorafenib (PROSORA-study) not-yet-due
Ongoing 2017-002837-48 HIV Eradication by combining Agents to reverse Latency in vivo (HEAL-1): a randomized controlled trial. not-yet-due
Ongoing 2017-003115-20 Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: a prospective randomised multicenter double-blind placebo-controlled clinical trial not-yet-due
Ongoing 2017-003535-11 The added value of the H2-antagonist ranitidine in premedication regimens during paclitaxel treatment not-yet-due
Ongoing 2017-004465-27 The effects of the proton pump inhibitor esomeprazole alone or in combination with Coca-Cola on the absorption of Capecitabine in patients with colorectal cancer or other solid tumours ' the COCA stud... not-yet-due
Ongoing 2017-004677-14 Dose IndividualizAtion of Beta-lactam and fluOroquinoLone AntiBiotics in ICU patients: to TDM or not to TDM and the effects on Outcome (DIABOLO-study) not-yet-due
Ongoing 2017-004735-37 Can Acetaminophen Ease the Heartbreak of Social Rejection? not-yet-due
Ongoing 2017-005124-24 Therapeutic Drug Monitoring guided tamoxifen dosing: a feasibility study in patients with hormone positive breast cancer not-yet-due
Ongoing 2018-000011-25 Avoiding tacrolimus under- and overexposure by using a new dosing algorithm for renal transplant recipients not-yet-due
Ongoing 2018-001631-46 Implementation of pharmacokinetic-guided dosing of DDAVP and VWF-containing concentrates in von Willebrand disease not-yet-due
Ongoing 2018-001696-21 Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk score - a randomized controlled trial not-yet-due
Completed, report not yet due 2018-002119-81 Carriage of S. aureus and interaction with the nasal microbiome 2020-09-01 not-yet-due
Ongoing 2018-002764-94 Adjuvant vaccination against HPV in surgical treatment of CIN lesions, a Randomised Controlled Trial not-yet-due
Ongoing 2018-002863-24 Intralesional steroid injections to prevent refractory strictures in patinets with esophageal atresia - a randomized controlled trial not-yet-due
Ongoing 2018-002914-10 FUnctional selection of advanced breast cancer patients for Talazoparib treatment Using the REpair Capacity (RECAP) test: The FUTURE trial not-yet-due
Ongoing 2018-003222-92 Dendritic cells loaded with allogeneic tumor cell lysate (PheraLys™) in surgically resected pancreatic cancer patients (REACtiVe Trial) not-yet-due
Ongoing 2018-003869-33 Implementation of pharmacokinetic-guided dosing of prophylaxis in hemophilia patients. not-yet-due
Ongoing 2018-003954-26 CYP3A4*22 genotype-guided dosing of TKIs in cancer patients: a new way of personalized therapy not-yet-due
Ongoing 2018-004013-41 Hepatic arterial infusion pump chemotherapy in patients with unresectable intrahepatic cholangiocarcinoma not-yet-due
Ongoing 2018-004091-35 Improving Treatment Options for Somatostatin Type 2 Receptor Negative Neuroendocrine Tumor Patients not-yet-due
Ongoing 2018-004239-63 Botulinum toxin (BOTOX®) to prevent post-operative pancreatic fistula in patients who undergo distal pancreatectomy. PROFIT study. not-yet-due
Ongoing 2018-004338-13 Short term clinical efficacy of topical treatment with clindamycin-benzoyl peroxide gel compared with clindamycin lotion in mild to moderate Hidradenitis Suppurativa not-yet-due
Ongoing 2018-004587-61 Deep profiling of lipid changes in patients with active ulcerative colitis treated with either tofacitinib or infliximab not-yet-due
Ongoing 2018-004724-11 Clinical effectiveness of 2 treat to target strategies, mimicking standard care compared to early secukinumab for the treatment of Moderate to Severe Psoriatic Arthritis: a parallel group randomised c... not-yet-due
Ongoing 2019-000216-29 Safety and efficacy of the addition of IMM-101 Heat-Killed Whole Cell Mycobacterium obuense to standard stereotactic radiotherapy in locally advanced pancreatic cancer patients (LAPC-2 trial). not-yet-due
Ongoing 2019-000276-41 Study on the effects of an OCT2/MATE1 substrate (metformin) and inhibitor (cimetidine) on the exposure of trifluridine/tipiracil (Lonsurf®) in patients with metastatic colorectal cancer (mCRC). not-yet-due
Exempt 2019-000657-31 Adoptive therapy with TCR gene-engineered T cells to treat patients with MAGE-C2-positive melanoma and head and neck cancer. not-yet-due
Ongoing 2019-000852-32 A preliminary study of Low Dose Naltrexone for the induction of remission in patients with mild to moderate Crohn’s Disease that failed conventional treatment: The LDN Crohn study. not-yet-due
Ongoing 2019-001317-16 The TRAIN study: TRAmetinib In Neurofibromatosis type 1 related symptomatic plexiform neurofibromas not-yet-due
Ongoing 2019-001425-26 Rotterdam Edoxaban Leaflet Evaluation in Patients after Transcatheter Aortic Valve Implantation not-yet-due
Ongoing 2019-001854-24 Long-term outcomes in immunologically low-risk kidney transplant recipients using tacrolimus. Extension study of: Tacrolimus monotherapy in immunologically low-risk kidney transplant recipients: a pil... not-yet-due
Ongoing 2019-002020-33 Pentoxifylline dose optimization in neonatal sepsis. not-yet-due
Ongoing 2019-002078-30 Autoimmune epilepsy Modulated by IVIg – effects on Cortical Excitability, the AMICE study not-yet-due
Ongoing 2019-002910-37 Study on the pharmacokinetic interaction between green tea and tamoxifen in patients with breast cancer. “the TEA study” not-yet-due
Ongoing 2019-003247-30 Use of the NMF biomarker as predictive diagnostic for effective use of cyclosporine in the treatment of atopic dermatitis. not-yet-due
Other 2019-003666-41 Doxapram versus placebo in preterm newborns: an international double blinded multicenter randomized controlled trial. not-yet-due
Ongoing 2019-003812-30 Primovist CT: proof of concept not-yet-due
Ongoing 2019-003966-42 Adjuvant hepatic arterial infusion pump chemotherapy after repeat hepatectomy for patients with recurrent colorectal liver metastases without a history of extrahepatic disease – a phase II study not-yet-due
Ongoing 2019-004148-31 The PREDMETH trial: Effectiveness of methotrexate versus prednisone as first-line therapy for pulmonary sarcoidosis – A randomized controlled trial not-yet-due
Completed, report not yet due 2019-004854-27 The influence of UGT inhibition on endoxifen exposure in cancer patients treated with tamoxifen: A proof of concept study. “The PROTAM study” 2020-10-24 not-yet-due
Ongoing 2020-000627-40 Azole-echinocandin combination therapy for invasive aspergillosis. A randomized pragmatic superiority trial (IA-DUET) not-yet-due
Ongoing 2020-000823-38 Study on the pharmacokinetic interaction between cabazitaxel and darolutamide in metastatic castration-resistant prostate cancer (mCRPC) patients. not-yet-due
Ongoing 2020-001527-14 COVID-19: addition of azithromycin to chloroquine treatment not-yet-due
Ongoing 2020-002802-21 PeRsonalIzed MEdicine in Rheumatoid Arthritis (PRIMERA trial): a multicenter, single-blinded, randomized controlled trial comparing usual care with a tailor-made approach not-yet-due
Ongoing 2020-003890-23 The nephroprotective effect of short hydration during cisplatin treatment in head and neck cancer patients. not-yet-due
Ongoing 2020-005445-16 Fasting before live kidney donation, effect on donor wellbeing and postoperative recovery not-yet-due
No trial status on register 2021-000444-22 Differences in coagulation between fresh frozen plasma and Solventdetergent plasma in pediatric congenital heart surgery bad-data
Ongoing 2021-000515-24 Vaccination Against Covid in Primary Immune Deficiencies not-yet-due
Exempt 2021-000864-32 A Phase I-II study of virus neutralizing antibodies against SARS-CoV-2. A focus on convalescent plasma and hyperimmune anti-SARS-CoV2 immunoglobulines not-yet-due