These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Listed as ongoing, but also has a completion date and reported results 2004-000446-20 A multi-centre randomised trial of therapeutic intervention at primary HIV-1 infection 2011-01-30 bad-data
Ongoing 2004-000798-71 Efficacy of Levetiracetam in Pendular Nystagmus: A Randomized, Double-blind, Placebo-controlled trial with crossover not-yet-due
Ongoing 2004-002051-13 A randomised double-blind placebo-controlled trial of oral misoprostol for cervical priming before outpatient hysteroscopy not-yet-due
Ongoing 2005-001030-33 PATCH not-yet-due
Ongoing 2005-001214-40 A trial to compare the effects of nebivolol versus atenolol on various cardiovascular measurements including insulin sensitivity not-yet-due
Ongoing 2005-001222-83 A phase I/II safety and tolerability dose escalation study following the autologous infusion of expanded adult haemopoietic stem cells to patients with liver insufficiency not-yet-due
Ongoing 2005-001525-28 INFLUENCE OF THE ANTIOXIDANT N-ACETYLCYSTEINE ON INHALED NITRIC OXIDE INDUCED PULMONARY RESPONSES FOLLOWING HUMAN LUNG ISCHAEMIA-REPERFUSION INJURY not-yet-due
Ongoing 2005-002585-11 CPAP;Heliox Effects on Stability and Therapeutics not-yet-due
Ongoing 2005-003007-36 B.R.E.A.T.H.E. Bronchiolitis RCT: Emergency Assisted Therapy with Heliox - an Evaluation. A Prospective, Double-Blinded, Randomised, Controlled Clinical Trial to assess the effect of helium-oxygen gas... not-yet-due
Ongoing 2005-003297-13 A randomised, double-blind, placebo-controlled, parallel-group study to investigate the effect of Symbicort® and Pulmicort® on HAT and HDAC expression and activity in induced sputum cells obtained fro... not-yet-due
Ongoing 2005-003344-62 Effect of theophylline on histone deacetylase activity: enhancement of in-vitro glucocorticoid function in patients with COPD. not-yet-due
Ongoing 2006-000280-28 A Phase I/II safety and tolerability dose escalation study following the autologous infusion of expanded adult haematopoietic stem cells to patients with established myocardial ischaemia. not-yet-due
Ongoing 2006-000281-36 A Phase I/II safety and tolerability study following autologous infusion of adult haematopoietic cells to patients with acute total anterior circulation ischaemic stroke not-yet-due
Ongoing, reported early 2006-001055-35 Lapatinib Pre-Surgical Phase 2 Study in Patients with Primary Breast Cancer not-yet-due
Ongoing 2006-001386-42 The timing of intra-vitreal (4mg) triamcinolone acetonide, in addition to verteporfin photodynamic therapy for choroidal neovascularisation, in age-related macular degeneration: a prospective randomis... not-yet-due
Listed as ongoing, but also has a completion date and reported results 2006-001859-35 Abatacept in ANCA associated vasculitis: ABAVAS 2009-03-25 bad-data
Ongoing 2006-002031-24 The HAM Ciclosporin Study: An observational trial of therapy in early or progressing HAM/TSP not-yet-due
Ongoing 2006-002123-17 Mechanistic study assessing the immunological response of subjects after treatment with different formulations of sublingual immunotherapy. not-yet-due
Ongoing 2006-002328-40 A phase I safety and tolerability study of infusing the autologous progeny of an adult CD34+ subset into patients with type I diabetes mellitus and a successful renal transplant. not-yet-due
Not reported 2006-003561-13 Reversal of steroid insensitivity in COPD by theophylline 2007-08-29 due-trials
Completed, report not yet due 2006-003833-33 Restoring Dystrophin Expression in Duchenne Muscular Dystrophy: A Phase I/II Clinical Trial Using AVI-4658 2009-03-31 not-yet-due
Completed, but no date 2006-004442-16 Modulation of lung injury complicating lung resection bad-data
Ongoing 2006-004521-28 A multi-centre phase I/II safety and tolerability study following the infusion of expanded autologous progeny of an adult CD34 positive stem cell subset to patients with recent tibial fractures. not-yet-due
Ongoing 2006-004705-26 Safety and Tolerability of Sildenafil in Patients with Eisenmenger Physiology not-yet-due
Ongoing 2006-005534-20 Effect of Erdosteine on inflammatory and oxidative biomarkers in sputum and exhaled breath in patients with COPD not-yet-due
Ongoing 2006-006212-30 A Randomised, Open labelled, Phase II, Immunogenicity, and Exploratory Efficacy Evaluation of Therapeutic Immunisations +/- IL-2, GM-CSF and Growth Hormone in HIV-1 Infected Subjects Receiving Highly ... not-yet-due
Ongoing 2006-006214-16 A randomised placebo controlled trial of rosuvastatin in systemic lupus erythematosus. not-yet-due
Ongoing 2006-006221-77 Warfarin Anticoagualtion for liver fibrosis in patients transplanted for hepatitis C virus infection. not-yet-due
Ongoing 2006-006347-31 A Phase II randomised placebo controlled clinical trial of Simvastatin in patients with secondary progressive multiple sclerosis not-yet-due
Not reported 2007-000438-38 Efficacy of Lopinavir in Pregnancy: Pharmacokinetic and Virological Studies with Kaletra melt extruded tablet formulation 2010-07-28 due-trials
Not reported 2007-000446-12 Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy 2009-07-08 due-trials
Ongoing 2007-000903-14 Randomized Phase III Trial to evaluate the effect of statins on tumour biology in non-small cell lung cancer. not-yet-due
Ongoing 2007-001222-27 The effect of Pioglitazone on vascular and ventricular function in people with type 2 diabetes PICCOLA not-yet-due
Ongoing 2007-002084-27 The pharmacokinetics and anti-inflammatory effects of prednisolone in severe asthma. not-yet-due
Ongoing 2007-002405-47 A randomised prospective study assessing changes in neuro-cognitive function, using a computerised test battery, in treatment naïve HIV-1 positive subjects commencing two different antiretroviral regi... not-yet-due
Reported results 2007-002411-36 LungstarPK: Multi centre Phase II Trial of Pravastatin added to chemotherapy with Cisplatin and Docetaxel in patients with non-small cell lung cancer. 2010-08-31 due-trials
Ongoing 2007-002466-35 A randomised placebo-controlled trial of fixed-dose combination medication in those at raised risk of cardiovascular disease not-yet-due
Completed, report not yet due 2007-004050-85 Evaluation of safety and gene expression with a single dose of pGM169/GL67A administered to the nose and lung of individuals with cystic fibrosis 2011-06-08 not-yet-due
Ongoing 2007-004856-35 Scavenging free haemoglobin atenuates the systemic inflmmatory response following surgery not-yet-due
Not reported 2007-005554-23 AN OPEN, NON-RANDOMISED PILOT STUDY OF ANTI-TNF-ALPHA THERAPY IN EARLY OR PROGRESSING HAM/TSP 2010-12-21 due-trials
Not reported 2007-006664-29 The effect of inhaled corticosteroids (ICS) on airway smooth muscle in asthma 2010-07-31 due-trials
Ongoing 2007-006692-37 The Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (IBDVit): IBDVit1 - Trial of Adjuvant Vitamin D with Corticosteroids in Active Crohn’s Disease; IBDVit2 - Trial of Adjuvant Vitamin... not-yet-due
Ongoing 2007-007156-33 Melatonin As A Novel Neuroprotectant in Preterm Infants- Dosage study not-yet-due
Ongoing 2007-007394-22 The role of white and grey matter and meningeal inflammation in multiple sclerosis (MS) and clinically isolated syndromes (CIS) as quantified using [(11)C](R)-PK11195 positron emission tomography (PET... not-yet-due
Ongoing 2008-001160-36 A trial of Guanfacine, an alpha 2 adrenergic agonist, for Spatial Neglect and Impaired Vigilance following Stroke and Focal Brain Damage not-yet-due
Not reported 2008-001466-93 Trial of adjuvant vitamin D with Infliximab in active Crohn's Disease (IBDVit2). 2010-05-01 due-trials
Not reported 2008-001467-10 Trial of Adjuvant Vitamin D with Standard Maintenance Therapy in Preventing Relapse of Inflammatory Bowel Disease 2010-05-01 due-trials
Not reported 2008-002139-34 The Pharmacokinetics of Inhaled Fluticasone Propionate delivered as Monodisperse Aerosols 2011-07-03 due-trials
Not reported 2008-004229-40 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Ankylosing Spondylitis (AS) 2011-01-18 due-trials
Ongoing 2008-004431-38 ACE inhibition and mechanisms of skeletal muscle weakness in COPD not-yet-due
Ongoing 2008-004740-36 Melatonin As A Novel Neuroprotectant In Preterm Infants−Trial Study not-yet-due
Reported results 2008-004803-78 Effectiveness of Transtympanic Steroids in unilateral Ménière's disease: a Randomised Controlled Double-Blind Trial 2015-04-13 due-trials
Not reported 2008-005924-97 A 12 week observational study to evaluate the effects of the initiation of chemotherapy with anti-angiogenic activity on neovascularisation (as determined by contrast enhanced ultrasound, (CEUS)) with... 2009-11-19 due-trials
Ongoing, reported early 2009-009235-30 Antidepressant controlled trial for negative symptoms in schizophrenia (ACTIONS) not-yet-due
Ongoing 2009-011208-42 First trimester progesterone therapy in women with a history of unexplained recurrent miscarriages: A randomised, double-blind, placebo-controlled, multi-centre trial [The PROMISE (PROgesterone in rec... not-yet-due
Listed as ongoing, but also has a completion date 2009-011538-93 A prospective, randomised study to access safety, changes in platelet reactivity, plasma cardiac biomarkers and metabolic parameters over 48 weeks in HIV-1 infected subjects undergoing a switch in an... 2013-01-31 bad-data
Ongoing 2009-011816-39 A randomised, open label, prospective study to assess two different therapeutic strategies following first treatment failure in HIV-1 infected subjects. ‘The First Failure Study’ : ‘FAST’ not-yet-due
Ongoing 2009-012424-87 T cells and TNF: The impct of TNF blockade on effector T cell populations in rheumatoid arthritis and other conditions treated with anti-TNF-alpha agents. not-yet-due
Listed as ongoing, but also has a completion date 2009-012451-18 "EUROACTION PLUS con intervención intensiva sobre el tabaco (vareniclina) durante un programa de cardiología preventiva para pacientes con enfermedad aterosclerosa establecida, individuos con alto rie... 2011-07-31 bad-data
Ongoing 2009-014042-28 What duration of intravenous antibiotic therapy should be used in the treatment of infective exacerbations of cystic fibrosis in patients chronically colonised with Pseudomonas aeruginosa? not-yet-due
Ongoing 2009-014292-52 Tacrolimus vs prednisolone for the treatment of nephrotic syndrome secondary to minimal change disease: A Randomised Control Trial not-yet-due
Ongoing, reported early 2009-014344-11 Neuroprotective effects of hypothermia combined with inhaled xenon following perinatal asphyxia - the TOBY Xe trial not-yet-due
Listed as ongoing, but also has a completion date 2009-016278-34 UMPIRE - Use of a Multidrug Pill In Reducing cv Events - a randomised controlled trial of fixed dose combination medication and usual care in those at high risk of cardiovascular disease. 2012-07-31 bad-data
Ongoing 2009-016678-34 Exploring the Relationship Between Insulin Resistance and Interferon Resistance: Options to Overcome HCV Non-Response to Pegylated Interferon not-yet-due
Reported results 2009-016731-34 Amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double blind controlled trial of Nutritional Evaluation and Optimisation in Neonates. 2013-12-23 due-trials
Not reported 2009-017636-41 Vasopressin and Corticosteroids in Septic Shock 2012-05-30 due-trials
Reported results 2010-018963-40 A multi-centre, double-blind, individually randomised, placebo-controlled, parallel arm RCT with 12-week follow-up to establish the clinical and cost effectiveness of amisulpride augmentation of cloza... 2015-03-25 due-trials
Reported results 2010-020226-17 An evaluation of the effect of an angiotensin-converting enzyme (ACE) inhibitor on the growth rate of small abdominal aortic aneurysms 2015-04-14 due-trials
Ongoing 2010-020440-35 GR activity in induced sputum macrophages, and a change in inflammatory biomarkers 2-hours after a single dose of either Symbicort®/Budesonide/Formoterol or placebo in Chronic Obstructive Pulmonary Di... not-yet-due
Not reported 2010-021515-17 RiFL: Rifaxamin in Fatty Liver Disease. Does Modulation of Gut Microbiota Reduce Hepatic Inflammation in Non-Alcoholic Steatohepatitis (NASH)? 2012-09-24 due-trials
Ongoing 2010-023325-37 UMPIRE Trial sub-study - Polypill Effects on Sub Clinical Atherosclerosis (PESCA): A randomised controlled trial of a cardiovascular polypill treatment strategy compared with usual care on carotid int... not-yet-due
Not reported 2010-023875-24 Anglo-Scandinavian Cardiac Outcomes Trial; Post Trial Follow-Up Study 2015-05-30 due-trials
Ongoing 2010-024048-14 A randomised-controlled trial of donepezil for motor recovery in acute stroke not-yet-due
Ongoing 2010-024585-22 What is the effect of intravenous iron supplementation on cardiopulmonary haemodynamics, exercise capacity and quality of life in patients with IPAH and iron deficiency? not-yet-due
Ongoing 2011-000454-32 A single arm phase IIa study (with combination safety run-in) to assess the safety and efficacy of AZD4547 in combination with either anastrozole or letrozole in ER positive breast cancer patients who... not-yet-due
Ongoing, reported early 2011-001093-26 A Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Oral Azithromycin (500 Mg OD) as a Supplement to Standard Care for Adult Patients with Acute Exacerbations of Asthma not-yet-due
Ongoing 2011-001148-31 A pilot clinical trial with the iron chelator Deferiprone in Parkinson's disease not-yet-due
Reported results 2011-001312-59 A double-blinded, randomized, crossover clinical study to assess the efficacy of Qutenza (capsaicin 8% patches) for the reduction of site pain caused by continuous subcutaneous infusion of Remodulin (... 2012-07-24 due-trials
Ongoing 2011-002598-49 The AXitinib MicroBubble UltraSound in metastatic Colorectal cancer trial not-yet-due
Ongoing, reported early 2011-002656-14 A randomised, prospective study, assessing changes in cerebral function in treatment naive HIV-1 infected subjects commencing either boosted atazanavir with Truvada or boosted darunavir with maraviroc... not-yet-due
Ongoing 2011-002744-27 Pharmacodynamic Studies of a Histone Deacetylase Inhibitor in FRDA not-yet-due
Ongoing, reported early 2011-004192-37 Hellenic Anglo Research into Morning Or Night antihypertensive drug deliverY trial. not-yet-due
Ongoing 2011-004761-33 A randomised double-blind placebo-controlled Phase 2B clinical trial of repeated application of gene therapy in patients with cystic fibrosis not-yet-due
Ongoing, reported early 2011-005240-10 A phase II, open label, preoperative study to assess the efficacy of the novel steroid sulfatase inhibitor Irosustat in postmenopausal women with early oestrogen receptor positive breast cancer. not-yet-due
Ongoing, reported early 2011-005363-24 Vasopressin vs Noradrenaline as Initial therapy in Septic Shock not-yet-due
Ongoing 2011-005544-10 Improving Inhaler Treatment and Small Airways Assessment in Chronic Obstructive Pulmonary Disease not-yet-due
Ongoing, reported early 2011-005680-25 A Phase II study to assess the safety and efficacy of the steroid sulfatase inhibitor Irosustat when added to an aromatase inhibitor in ER positive locally advanced or metastatic breast cancer patient... not-yet-due
Ongoing 2012-000413-36 ACE-EPIC: ACE inhibitors to enhance the effects of pulmonary rehabilitation in COPD not-yet-due
Ongoing, reported early 2012-000424-18 A study to assess near infrared laparoscopy with indocyanine green (ICG) for intraoperative lymphatic imaging and sentinel lymph node identification during standard surgical resection for colonic canc... not-yet-due
Ongoing 2012-002198-72 Targeted retreatment of incompletely recovered COPD exacerbations with ciprofloxacin: a double-blind, randomised, placebo-controlled, multicentre Phase III trial not-yet-due
Ongoing 2012-002199-15 A Phase III double-blind, randomised, placebo controlled trial of long term therapy on Exacerbation Rate in patients with stable COPD using Doxycycline not-yet-due
Ongoing 2012-002357-35 Stem cells in Rapidly Evolving Active Multiple Sclerosis (STREAMS) not-yet-due
Ongoing 2012-002969-35 Slow-wave sleep and daytime functioning in chronic fatigue syndrome: effects of sodium oxybate not-yet-due
Ongoing, reported early 2012-003136-23 Lamotrigine And Borderline Personality Disorder: Investigating Long-Term Effectiveness not-yet-due
Ongoing 2012-003581-40 A prospective, observational study to examine the effects of ageing on the clinical outcomes of people living wih HIV in England and Ireland. not-yet-due
Ongoing 2012-003817-32 Brain muscle axis during treatment of hepatic encephalopathy with L-ornithine L-aspartate not-yet-due
Completed, report not yet due 2012-004893-25 RITUXILUP - An open label randomised multicentre controlled trial of RITUXImab and mycophenolate mofetil (MMF) without oral steroids for the treatment of LUPus nephritis 2017-12-13 not-yet-due
Ongoing, reported early 2012-005159-18 An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS) not-yet-due
Ongoing 2013-000962-13 Evaluating the effects of the novel GLP-1 analogue, liraglutide, in patients with Alzheimer’s disease (ELAD study) not-yet-due
Ongoing 2013-003196-35 Assessing the subjective intensity of oral psilocybin in patients with treatment-resistant depression: A Pilot Study not-yet-due
Ongoing 2013-003732-72 Randomised placebo-controlled study of grass pollen allergen immunotherapy tablet (AIT) for seasonal rhinitis: time course of nasal, cutaneous and immunological outcomes not-yet-due
Ongoing 2013-004333-33 Phase 1 of dose escalation of extracorporeal shockwave treatment only and in combination DPP-4 inhibitor and parathyroid hormone (non-randomised, open-labelled) & Phase II of combination treatments of... not-yet-due
Ongoing 2014-001244-38 Preventing Recurrent Gestational Diabetes Mellitus with Early Metformin Intervention not-yet-due
Ongoing 2014-001425-32 RIVER - Research In Viral Eradication of HIV Reservoirs, A two-arm (proof of concept) randomised phase II trial not-yet-due
Ongoing, reported early 2014-003077-42 A single-centre, double-blind, randomised, placebo-controlled crossover study to evaluate the effect of solithromycin on airway inflammation in male and female patients with chronic obstructive pulmon... not-yet-due
Ongoing 2014-003710-84 The Central Nervous System Effects of Two Different HIV-Integrase Inhibitor Containing Antiretroviral Regimens. not-yet-due
Ongoing 2014-003923-23 GLP-1 Receptor Agonist interVentIon for poor responders afTer bariAtric Surgery: The GRAVITAS trial not-yet-due
Ongoing 2014-004112-11 ALERT: A phase II study of alternating eribulin and hormonal therapy in pre-treated ER+ve breast cancer not-yet-due
Ongoing 2015-001615-13 TARGETING OF THE SMALL AIRWAYS IN PATIENTS WITH COPD: AIRWAY EFFECTS OF TIOTROPIUM -Respimat vs. Handihaler not-yet-due
Ongoing 2015-002309-12 A randomised controlled trial of the sulfonylurea Gliclazide and the DPP4 inhibitor Linagliptin on the frequency of hypoglycaemia among patients with Type 2 Diabetes and chronic kidney disease (CKD) s... not-yet-due
Ongoing 2015-002555-10 Effect of the CRTH2 antagonist OC459 on the response to rhinovirus challenge in asthma not-yet-due
Ongoing, reported early 2015-002955-85 A feasibility study to assess the effects of AntiretroViral Intensification with Cenicriviroc for the management of HIV-associated Cognitive Impairment. The AVICCI study not-yet-due
Ongoing 2015-004109-18 Self-Assessment Method for Statin side-effects Or Nocebo (SAMSON) trial. not-yet-due
Ongoing 2015-005004-28 Stratified Treatment OPtimisation for HCV-1 (STOPHCV-1) not-yet-due
Ongoing 2016-001010-17 Nucleos(t)ide withdrawal in HBeAg negative hepatitis B virus infection to promote HBsAg clearance. (NUC-B) not-yet-due
Ongoing 2016-002547-42 Open-Label Proof of Concept Feasibility Study to Explore the Safety, Tolerability and Potential Role of MDMA-Assisted Psychotherapy for the Treatment of Detoxified Patients with Alcohol Use Disorder. not-yet-due
Ongoing 2016-002598-36 Randomised Clinical Trial of Noradrenergic Add-on Therapy with Extended-Release Guanfacine in Alzheimer's Disease not-yet-due
Ongoing 2016-002628-96 A multi-centre, double-blind, randomised, controlled clinical trial of Rifaximin to reduce infection in patients admitted to hospital with decompensated cirrhosis not-yet-due
Ongoing 2016-004797-18 Pilot study of the GLP-1 agonist, Liraglutide, on decreasing parenteral support requirements in short bowel patients. not-yet-due
Ongoing 2017-000219-18 Psilocybin vs. escitalopram for major depressive disorder: comparative mechanisms not-yet-due
Ongoing 2017-003172-32 Maraviroc Add-on Therapy for Steatohepatitis in HIV not-yet-due