These trials completed more than 12 months ago and should have reported results.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Reported results 2004-000452-16 International, Multicenter, Study of One-Year, Open-Label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia Extention to Studies 156-02-235 and 156-03-238 to Asses ... 2009-10-27 due-trials
Listed as ongoing, but also has a completion date and reported results 2004-000611-25 A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, 52-Week Dose Comparison Study of the Efficacy and Safety of 25mg QD and 50mg QD of OPC-6535 Oral Tablets and 800 mg BID of Asacol® in th... 2007-01-17 bad-data
Reported results 2005-002306-39 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long Term Efficacy and Safety of Oral Tolvaptan Tablets in Subjects Hospitalized with Worsening Congestive Heart Failure 2006-07-05 due-trials
Listed as ongoing, but also has a completion date and reported results 2005-003724-19 A Phase 3, Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-arm Study of the Efficacy and Safety of OPC-6535 Tablets in the Treatment of Subjects with Active Ulcerative Colitis 2006-07-04 bad-data
Listed as ongoing, but also has a completion date and reported results 2006-002768-24 A Phase 3, Multi-center, Double-blind, Placebo-controlled, Parallel-arm Trial to Determine Long-term Safety and Efficacy of Oral Tolvaptan Tablet Regimens in Adult Subjects with Autosomal Dominant Pol... 2012-01-23 bad-data
Reported results 2007-005229-31 A Multi center, Randomized, Double-blind, Placebo-controlled Phase 2 Trial to Evaluate the Safety, Efficacy and Pharmacokinetics of Multiple Doses of OPC-67683 in Patients with Pulmonary Sputum Cultu... 2010-06-22 due-trials
Reported results 2008-002675-27 A 52-week, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of an Intramuscular Depot Formulation of Aripiprazole (OPC-14597) as Maint... 2011-02-03 due-trials
Listed as ongoing, but also has a completion date and reported results 2008-002676-10 A 38-week, Multicenter, Randomized, Double-blind, Active-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of an Intramuscular Depot Formulation of Aripiprazole (OPC-14597) as Mainte... 2012-08-31 bad-data
Listed as ongoing, but also has a completion date and reported results 2008-002699-83 A 52-week, Multicenter, Open-label Study to Evaluate the Effectiveness of Aripiprazole Intramuscular Depot as Maintenance Treatment in Patients with Schizophrenia 2013-10-07 bad-data
Reported results 2008-005107-26 A Phase 2, Multi-center, Uncontrolled, Open-label Trial to Evaluate Safety, tolerability, and Efficacy of Orally Administered OPC-67683 as 100 mg BID with optional titration to 200 mg BID for up to S... 2011-09-22 due-trials
Reported results 2009-012567-33 A Phase 2, 6-Week, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Oral OPC-34712 Once Daily and Aripiprazole Once Daily for Treat... 2010-09-16 due-trials
Listed as ongoing, but also has a completion date and reported results 2009-012568-14 A Phase 2, Multicenter, Open-label Study to Assess the Safety and Tolerability of Oral OPC-34712 as Monotherapy in Adult Patients with Schizophrenia 2012-03-06 bad-data
Reported results 2009-014944-13 A Phase 2, Multi-center, Non-controlled, Open-label Dose Escalation Trial to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of Orally Administered OPC-67683 Two Times Daily to Patient... 2011-05-12 due-trials
Listed as ongoing, but also has a completion date and reported results 2010-018401-10 A Multi-center, Open-label, Extension Study to Evaluate the Long-term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects with Autosomal Dominant Polycystic Kidney Disease (ADPKD) 2016-02-29 bad-data
Reported results 2010-018796-21 A Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Patients with Major Depressive Disorder. 2011-07-12 due-trials
Listed as ongoing, but also has a completion date and reported results 2010-018858-12 A Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Patients with Major Depressive Disorder. 2011-07-12 bad-data
Listed as ongoing, but also has a completion date and reported results 2010-018859-97 A Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Patients with Major Depressive Disorder. 2011-07-12 bad-data
Reported results 2010-018860-17 A Multicenter, 52-week, Open-label Study to Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Patients with Major Depressive Disorder 2011-07-12 due-trials
Reported results 2010-018911-13 A Long-term, Multicenter, Open-Label Study to Evaluate the Safety and Tolerability of Flexible-Dose Oral Aripiprazole (OPC-14597) as Maintenance Treatment in Adolescent Patients with Schizophrenia or ... 2014-07-09 due-trials
Completed, but no date, and reported results 2010-019025-33 A Phase IIa, Single-Center Study, Investigating the Short-Term Renal Hemodynamic Effects, Safety and Pharmacokinetics/Pharmacodynamics of Oral Tolvaptan (OPC-41061) in Subjects with Autosomal Dominant... bad-data
No trial status on register 2010-020987-39 A Long-Term Multicenter, Randomized, Double-blind, Placebocontrolled Study to Evaluate the Efficacy, Safety, and Tolerability of Aripiprazole (OPC-14597) as Maintenance Treatment in Adolescent Patient... bad-data
Ongoing 2010-021143-41 An Open-Label, Multicenter, Rollover, Long-term Study of Aripiprazole Intramuscular Depot in Patients with Schizophrenia not-yet-due
Reported results 2010-022271-59 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Trial to Evaluate the Safety and Efficacy of Delamanid (OPC-67683) Administered Orally as 200 mg Total Daily Dose f... 2016-07-04 due-trials
Reported results 2010-024595-26 Phase 2 Placebo-controlled Double-blind Trial of Dasatinib Added to Gemcitabine for Subjects with Locally-advanced Pancreatic Cancer 2015-06-15 due-trials
Reported results 2011-000467-27 A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Efficacy of Flexible-Dose Once-weekly Oral Aripiprazole in Children and Adolescents with Tourette's Disorder 2013-11-06 due-trials
Completed, but no date, and reported results 2011-000468-83 A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Efficacy of Fixed-Dose Once-weekly Oral Aripiprazole in Children and Adolescents with Tourette’s Disorder bad-data
Listed as ongoing, but also has a completion date and reported results 2011-000469-11 An Open-Label, Multicenter Study Evaluating the Safety and Tolerability of Once-weekly Oral Aripiprazole in Children and Adolescents with Tourette’s Disorder 2014-03-14 bad-data
Reported results 2011-001349-33 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults with Major Depres... 2013-09-12 due-trials
Reported results 2011-001350-28 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of Fixed-dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults with Major Depressive Dis... 2013-05-02 due-trials
Reported results 2011-001351-37 A Long-term, Phase 3, Multicenter, Open-label Trial to Evaluate the Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults with Major Depressive Disorder, the Orion Trial. 2017-05-18 due-trials
Reported results 2011-002513-11 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Fixed dose OPC-34712 (4, 2, and 1 mg/day) in the Treatment of Adults With Acute Schizophrenia 2014-01-29 due-trials
Reported results 2011-002514-37 A Long-term, Phase 3, Multicenter, Open-label Trial to Evaluate the Safety and Tolerability of Oral OPC-34712 as Maintenance Treatment in Adults with Schizophrenia 2016-02-25 due-trials
Reported results 2011-002538-38 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Three Fixed Doses of OPC-34712 in the Treatment of Adults With Acute Schizophrenia 2013-12-05 due-trials
Reported results 2011-003850-26 A Multicenter, Open-label Study to Assess Hospitalization Rates in Adult Subjects with Schizophrenia Treated Prospectively for 6 Months with Aripiprazole IM Depot Compared with 6-month Retrospective T... 2012-05-24 due-trials
Reported results 2011-005766-38 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults with Schiz... 2015-02-12 due-trials
Reported results 2012-002870-30 A 52-week, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of an Intramuscular Depot Formulation of Aripiprazole (OPC-14597) as Maint... 2016-04-09 due-trials
Listed as ongoing, but also has a completion date and reported results 2012-003488-23 A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescents with Tourette’s Disorder 2013-09-03 bad-data
Listed as ongoing, but also has a completion date and reported results 2012-003489-42 An Open-Label, Multicenter Study Evaluating the Safety and Tolerability of Once-daily Oral Aripiprazole in Children and Adolescents with Tourette’s Disorder 2014-10-27 bad-data
Reported results 2012-003805-86 A 12-week, Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in the Acute Treatment of Adults With Schizophrenia 2013-08-30 due-trials
Reported results 2012-003806-28 A 26-week, Multicenter, Open-label, Extension Study of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in Patients with Schizophrenia 2014-02-17 due-trials
Reported results 2012-003948-67 A Phase 3, Multicenter, Randomized, Double-blind, Placebo- and Active Comparator-controlled 2016-11-10 due-trials
Reported results 2012-004334-42 A 52-week, Multicenter, Open-label Study to Evaluate the Effectiveness of an Intramuscular Depot Formulation of Aripiprazole (OPC-14597) as Maintenance Treatment in Patients with Bipolar I Disorder 2016-11-18 due-trials
No trial status on register 2012-004473-25 Phase 1, Open-label, Multiple-dose, and Age De-escalation Trial to bad-data
Listed as ongoing, but also has a completion date and reported results 2013-000503-17 A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Flexible Dosing of Brexpiprazole (OPC-34712) in the Treatment ... 2017-03-30 bad-data
Reported results 2013-000504-41 A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole (OPC-34712) in the Treatment of... 2017-03-15 due-trials
Completed, reported early 2013-001249-15 A Two-Part Phase 1/2a, Open-Label, Dose-Escalation Study to Evaluate the Tolerability and Preliminary Antitumour Activity of OPB-111001 in Patients with Advanced Cancers that are Poorly Responsive to ... 2015-09-08 not-yet-due
Completed, reported early 2013-002005-59 A Phase 3b, Multicenter, Open-label, Randomized Withdrawal Trial of the Effects of Titrated Oral SAMSCA® (Tolvaptan) on Serum Sodium, Pharmacokinetics, and Safety in Children and Adolescent Subjects H... 2018-07-24 not-yet-due
Listed as ongoing, but also has a completion date 2013-002810-11 A Phase 3b, Multicenter, Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Subjects With Euvolemic or Hypervolemic Hyponatremia Who Have Previously Participated in ... 2017-10-23 bad-data
Reported results 2013-003899-12 Protocol 271-12-205: A Phase 2 Multi-center, Randomized, Double-blind, Vehicle-controlled, Three-arm, Parallel Group Study to Assess the Safety, Tolerability, and Efficacy of Topical OPA-15406 Ointmen... 2015-01-28 due-trials
Reported results 2014-000062-22 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults with Majo... 2016-05-23 due-trials
Listed as ongoing, but also has a completion date and reported results 2014-000226-38 A Phase 3b, Multi-center, Randomized-withdrawal, Placebo-controlled, Double-blind, Parallel-group Trial to Compare the Efficacy and Safety of Tolvaptan (45 to 120 mg/day, Split-dose) in Subjects with ... 2017-04-14 bad-data
Listed as ongoing, but also has a completion date 2014-000424-23 A 2-month, Observational, Rollover Trial to Evaluate the Safety of Subjects with Agitation Associated with Dementia of the Alzheimer's Type who were Previously Treated with Brexpiprazole (OPC-34712) o... 2017-06-30 bad-data
Listed as ongoing, but also has a completion date 2014-001501-41 A Multinational Trial to Collect Blood Samples to Explore Potential Genetic/Biomarkers Related to Increased Risk of Liver Injury in Adult Subjects from Prior Tolvaptan Clinical Trials for Autosomal Do... 2016-08-07 bad-data
Ongoing 2014-001516-19 A Phase 3b, Multi-center, Open-label Trial to Evaluate the Long Term Safety of Immediate-release Tolvaptan (OPC 41061, 30 mg to 120 mg/day, Split dose) in Subjects with Autosomal Dominant Polycystic K... not-yet-due
Listed as ongoing, but also has a completion date 2014-001582-27 A Pilot Phase 3b, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of the Safety, Efficacy, and Pharmacokinetics of Titrated Oral SAMSCA® (Tolvaptan) in Children and Adolescent Subjects... 2017-06-22 bad-data
Ongoing 2016-000187-42 A Phase 3b, Two-part, Multicenter, One Year Randomized, Double-blind, Placebo-controlled Trial of the Safety, Pharmacokinetics, Tolerability, and Efficacy of Tolvaptan followed by a Two Year Open-labe... not-yet-due
No trial status on register 2016-005111-40 A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Flexible- bad-data
No trial status on register 2017-000174-11 Safety and Efficacy of Aripiprazole in the Long-Term Maintenance bad-data
No trial status on register 2017-000175-86 A 52-Week, Open-label, Multicenter Study of the Safety and Tolerability bad-data
Ongoing 2017-002190-20 A Multicenter, Randomized, Double-blind Trial of Brexpiprazole versus Placebo for the Acute Treatment of Manic Episodes, With or Without Mixed Features, Associated With Bipolar I Disorder not-yet-due
Ongoing 2017-002222-20 A Multicenter, Randomized, Double-blind Trial of Brexpiprazole versus Placebo for the Acute Treatment of Manic Episodes, With or Without Mixed Features, Associated With Bipolar I Disorder not-yet-due
Ongoing 2017-002225-38 A Multicenter, Open-label Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects with Bipolar I Disorder not-yet-due
Ongoing 2017-003940-19 A Phase 3, 12-Week, Multicenter, Randomized, Double-blind, Placebo controlled, 2 Arm, Fixed-dose Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) in the Treatment ... not-yet-due