These trials completed more than 12 months ago and should have reported results.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Reported results 2004-000629-32 Multicentre international study of capecitabine ± bevacizumab as adjuvant treatment of colorectal cancer 2014-03-31 due-trials
Reported results 2004-000658-22 The Second Multi-Centre Intra-Pleural Sepsis Trial (MIST2), to assess whether DNase or Alteplase improves pleural fluid drainage in pleural infection. 2009-12-22 due-trials
Reported results 2004-001156-37 Study of Heart and Renal Protection 2010-09-02 due-trials
Reported results 2004-001981-41 Bipolar Affective disorder: Lithium/ANti-Convulsant Evaluation 2008-06-30 due-trials
Reported results 2004-003341-40 PRE-EMPT: Prevention of Mood Disorders by Folic Acid Supplement. 2010-04-27 due-trials
Reported results 2004-003836-77 AspECT - A phase III, randomised study of aspirin and esomeprazole chemoprevention in Barrett's metaplasia & oesophagitis. 2017-05-31 due-trials
Reported results 2004-004290-29 Randomised controlled trial of effect of antibiotic dose on antibiotic resistance in young children with otitis media 2006-04-30 due-trials
Reported results 2005-000500-13 Metformin treatment before IVF in women with ultrasound evidence of polycystic ovaries; a prospective, randomised, double blind, placebo controlled study 2008-07-01 due-trials
Exempt, with results 2005-001041-42 Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with the virosomal vaccine PEV3A and FP9-MVA ME-TRAP 2006-02-22 not-yet-due
Reported results 2005-005226-31 TIME 1 The First Therapeutic Intervention in Malignant Pleural Effusion Trial (TIME1) A 2 x 2 randomised factorial trial to assess whether non-steroidal anti-inflammatory analgesics and small bore ch... 2014-04-15 due-trials
Reported results 2005-005664-88 Prospective Study of Mycobacterium Tuberculosis Specific Cellular immune Responses in Iatrogenically Immunosuppressed Patients: those undergoing TNF-alpha blockade or Awaiting Renal Trasnplants: A Pot... 2006-07-14 due-trials
Reported results 2005-006141-16 A Randomised, Placebo-Controlled Study of Two Doses of Oral 6R-BH4 on Vascular Function in Subjects with Coronary Artery Disease 2009-06-09 due-trials
Reported results 2005-006174-97 Which oxygen saturation level should we use for very premature infants? A randomised controlled trial (BOOST-II UK) 2010-12-24 due-trials
Reported results Terminated 2006-001317-15 BALANCE 2: Bipolar disorder:Antidepressant/Lamotrigine/ANtipsychotic Comparative Evaluation 2006-09-15 due-trials
Reported results 2006-001885-17 HPS2-THRIVE (Treatment of HDL to Reduce the Incidence of Vascular Events): A randomized trial of the long-term clinical effects of raising HDL cholesterol with MK 524A (ER niacin and laropipirant). 2012-11-14 due-trials
Reported results 2007-001349-17 A single centre, open-label, randomised clinical trial to investigate Meningococcal serogroup A, C, W-135 and Y saccharide specific B cell response to a primary and a booster dose of the Meningococcal... 2010-10-05 due-trials
Reported results Terminated 2007-004360-44 Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with AdCh63 ME-TRAP and MVA ME-TRAP 2008-11-26 due-trials
Reported results 2007-004513-33 Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression 2013-04-27 due-trials
Reported results 2007-005224-32 A randomised controlled trial of the angiotensin converting enzyme inhibitor ramipril in asymptomatic aortic stenosis 2012-06-01 due-trials
Reported results 2007-005389-11 A Phase I/IIa Study of the Safety, Immunogenicity and Parasite Growth Inhibitory Activity of AMA1-C1/Alhydrogel® + CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium falciparum Malaria 2010-09-28 due-trials
Reported results 2007-005391-13 Cancer Oesophagus Gefitinib(COG) - Phase III randomised, double-blind, placebo-controlled trial of gefitinib (Iressa®) versus placebo in oesophageal cancer progressing after chemotherapy. 2012-05-18 due-trials
Reported results 2008-000281-23 Melatonin in Acute Mania Investigation (MIAMI-UK) 2013-03-31 due-trials
Reported results 2008-000586-26 Adjuvant Urokinase in the Treatment of Malignant Pleural Effusion: The Third Therapeutic Intervention in Maligant Effusion Trial (TIME3-UK). A Randomised Controlled Trial to evaluate whether use of in... 2015-06-26 due-trials
Reported results 2008-001024-31 A randomised controlled trial of iodide supplementation in preterm infants with follow-up at 2 years 2015-04-22 due-trials
Reported results Terminated 2008-004785-98 An observational study of children immunised in infancy against hepatitis B virus, evaluating the persistence of immunity and the immune response to a scheduled booster dose of hepatitis B vaccine 2011-01-27 due-trials
Reported results 2008-005759-21 Can atorvastatin improve vascular function in women with a history preeclampsia? A Randomised, double-blinded, placebo-controlled crossover trial of atorvastatin in women with a history of preeclampsi... 2013-01-14 due-trials
Reported results 2008-006302-42 A Phase II study in patients with locally advanced pancreatic carcinoma: ARC-II – Akt-inhibition by Nelfinavir plus chemoradiation with gemcitabine and cisplatin 2015-05-27 due-trials
Reported results 2008-006486-88 Modafinil for the treatment of fatigue in lung cancer: a multicentre, randomised, double-blinded, placebo-controlled trial 2012-06-11 due-trials
Reported results 2008-006804-46 Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with AdCh63 ME-TRAP and MVA ME-TRAP 2011-02-28 due-trials
Other 2008-008553-27 Open-label, randomised multicentre study of CAMPATH-1H versus basiliximab induction treatment and sirolimus versus tacrolimus maintenance treatment for the preservation of renal function in patients r... not-yet-due
Reported results 2009-009323-11 A randomised controlled trial of natural versus hormone replacement therapy cycles in frozen embryo replacement IVF: a pilot study 2013-05-14 due-trials
Reported results Terminated 2009-010334-21 A phase IIa study to assess the safety and efficacy of a new influenza vaccine candidate MVA-NP+M1 in healthy adults. 2010-10-26 due-trials
Reported results 2009-011228-73 A pilot study of Aripiprazole treatment for antipsychotic induced hyperprolactinaemia in young patients with severe mental illness and learning disabilities. 2014-12-31 due-trials
Exempt, with results 2009-012591-27 A phase I/IIa study to assess the safety and immunogenicity of new malaria vaccine candidates AdCh63 MSP1 alone and with MVA MSP1 2010-09-22 not-yet-due
Other 2009-013228-21 Prevention of atrial oxidative stress and electrical remodelling in patients undergoing cardiac surgery: randomised placebo-controlled trial of perioperative high-dose atorvastatin not-yet-due
Reported results 2009-014469-19 Evaluation of Mirtazapine and Folic Acid for Schizophrenia: A Large Simple 2x2 Factorial Trial. 2014-08-18 due-trials
Reported results 2009-014719-11 Open Label, Randomized, Parallel-Group, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Baxter H1N1 vaccine and GlaxoSmithKline H1N1 vaccine in children 6 months to 12 ye... 2011-05-24 due-trials
Reported results 2009-016459-23 Single arm NCRI feasibility study of CHOP in combination with Ofatumumab in induction and maintenance for patients with newly diagnosed Richter’s Syndrome 2016-04-19 due-trials
Reported results 2009-016579-31 An open label randomised controlled study to evaluate the induction of immune memory following infant vaccination with a glyco-conjugate Neisseria meningitidis serogroup C vaccine and to assess the im... 2014-10-13 due-trials
Reported results 2009-016846-16 Phase II Clinical Trial of 6-Mercaptopurine(6MP)and low-dose Methotrexate In Patients With Known BRCA Defective Tumours. 2017-02-16 due-trials
Reported results 2009-017498-39 A follow-on, multi-centre, open-label, clinical, phase 3 trial to investigate the persistence of serotype-specific antibodies at 40 months of age in children who have received either the 7-valent or t... 2012-12-10 due-trials
Reported results 2009-018153-23 A double blind randomised phase 2 trial of docetaxel with or without AZD6244 in wt BRAF advanced melanoma 2020-02-20 due-trials
Reported results 2010-018341-56 A phase I/IIa sporozoite challenge study to assess the safety, immunogenicity and protective efficacy of new malaria vaccine candidates; AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & ... 2011-03-15 due-trials
Reported results 2010-019091-78 An observational study into the maintenance of seroprotection against Meningococcal serogroup C disease throughout childhood following a single dose of a conjugated Meningococcal serogroup C vaccine a... 2011-05-16 due-trials
Reported results 2010-019647-19 A double blind randomised placebo controlled trial of montelukast in the treatment of acute persistent cough in young people and adults (aged 16-49) in primary care 2012-10-23 due-trials
Reported results Terminated 2010-020621-40 SONATINA: A Phase II Multi-Centre Randomised Controlled Study of Nelfinavir Addition to Radiotherapy Treatment in Neo-Adjuvant Therapy for Rectal Cancer 2014-01-07 due-trials
Reported results Terminated 2010-022589-29 Investigation of pathways regulating cell survival and early antiangiogenic response to single agent Everolimus or Rapamycin in renal cancer 2012-10-04 due-trials
Reported results 2010-022817-24 A multi-centre, open-label, clinical, phase 4 trial, following on from a head-to-head comparison study of two H1N1 influenza vaccines in children, to compare firstly, the persistence of antibody again... 2011-08-05 due-trials
Ongoing, reported early 2010-023467-18 HPS 3 / TIMI 55: REVEAL (Randomized EValuation of the Effects of Anacetrapib through Lipid-modification): A large-scale, randomized placebo-controlled trial of the clinical effects of anacetrapib amo... not-yet-due
Other 2011-000381-35 Understanding typhoid disease after vaccination: a single centre, randomised, double-blind, placebo-controlled study to evaluate M01ZH09 in a healthy adult challenge model, using Ty21a vaccine as a po... not-yet-due
Reported results 2011-000661-12 A randomised double blind phase 2 trial of whole brain radiotherapy with or without vandetanib in metastatic melanoma with brain metastases 2014-11-28 due-trials
Reported results 2011-002038-37 Hyperpolarised xenon magnetic resonance imaging (Xe-129 MRI) lung imaging in COPD 2017-08-23 due-trials
Reported results 2011-002545-35 A randomised phase 2 study of paclitaxel with or without GSK1120212 in advanced wt BRAF melanoma 2016-12-31 due-trials
Reported results 2011-003123-35 The impact of single versus double dose acetylsalicylic acid on platelet function in patients with type 2 diabetes (the "ASP Study"). 2013-01-18 due-trials
Reported results Terminated 2011-003311-27 Vascular Targeted Photodynamic therapy with WST11 for T1a Renal Tumours. PHASE IIa histological follow up trial 2016-09-09 due-trials
Reported results 2011-005102-30 A phase III randomised, open label clinical trial evaluating the immunogenicity of a 10-valent pneumococcal conjugate vaccine booster compared to the standard 13-valent pneumococcal conjugate vaccine ... 2014-10-13 due-trials
Reported results 2011-005477-24 A Phase I/IIa Sporozoite Challenge Study to Assess the Protective Efficacy of Two Prime-boost Malaria Vaccine Candidates: ChAd63 and MVA encoding ME-TRAP and the same Viral Vectors encoding CS 2012-11-07 due-trials
Reported results 2011-005763-24 BEST-D (Biochemical efficacy and safety trial of vitamin D): a dose-finding trial assessing biochemical and vascular effects of high dose vitamin D 2014-03-10 due-trials
Reported results 2012-000147-27 A Single-Blind Randomised Controlled Pilot trial of Corticosteroid Injection for Shoulder Pain 2013-03-31 due-trials
Reported results 2012-000615-84 A Mechanistic Study Of Mifamurtide (MTP-PE) In Patients With Metastatic And/Or Recurrent Osteosarcoma 2016-12-09 due-trials
Reported results 2012-000616-28 Phase II trial of Linsitinib (anti-IGFR/IR) in patients with relapsed and/or refractory Ewing Sarcoma 2016-07-15 due-trials
Reported results 2012-002443-26 A phase II, multi-centre, open labelled randomised control trial to describe immune & transcriptomic responses to trivalent inactivated vaccine (TIV) & MF59 adjuvanted influenza vaccine (ATIV) in 14 -... 2014-10-13 due-trials
Other 2012-002672-13 Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) Trial: a prospective randomised open blinded endpoint trial to determine the effect of aldosterone receptor antagonism ... not-yet-due
Reported results 2012-002952-17 Effects of intravenous iron on hypoxic pulmonary responses in COPD 2017-07-05 due-trials
Reported results Terminated 2012-003191-39 The effect of a single-dose of d-cycloserine on the basic effects of cognitive-behaviour therapy for panic disorder - a randomized placebo-controlled trial 2017-09-27 due-trials
Reported results 2012-004260-22 A multi-centre randomised placebo-controlled trial of prophylactic enteral lactoferrin supplementation to prevent late-onset invasive infection in very preterm infants. 2018-05-03 due-trials
Reported results 2012-004330-41 Do oral corticosteroids provide clinical and cost-effective symptom relief for sore throat? A multi-centre, double blind, randomized, placebo-controlled trial. 2015-04-16 due-trials
Reported results 2012-004416-66 A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches using the ChAd63 and MVA vectors encoding the antigens ME-TRAP, CS and AMA1. 2013-10-14 due-trials
Reported results Terminated 2012-004954-27 A single centre open-label randomised controlled trial of long term pituitary down-regulation before in vitro fertilisation for women with endometriosis: a pilot study 2013-11-07 due-trials
Other 2012-004980-39 A double blind randomised controlled trial on neuroprotection of amiloride in optic neuritis not-yet-due
Reported results 2013-000393-30 A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of the Combination Malaria Vaccine Candidate Regimen of RTS,S/AS01B + ChAd63 and MVA encoding ME-TRAP and also RTS... 2014-08-21 due-trials
Reported results 2013-001024-19 An open label single-arm study of the immunogenicity and reactogenicity of a 13-valent pneumococcal conjugate vaccine (Prevenar13®) given to children with type 1 diabetes mellitus who have not previou... 2018-12-31 due-trials
Reported results 2013-002259-14 The effect of lixisenatide in type 1 diabetes 2017-02-09 due-trials
Reported results 2013-002822-21 The early use of Antibiotics for at Risk CHildren with InfluEnza in primary care (ARCHIE): a double-blind randomised placebo-controlled trial 2019-08-15 due-trials
Reported results 2013-003488-71 A pilot study of the impact of BCG administration on the immunogenicity of serogroup C meningococcal conjugate vaccine in healthy infants 2018-06-27 due-trials
Other 2013-004968-56 A multi-centre randomised study of induction chemotherapy followed by capecitabine (+/-nelfinavir) with high or standard dose radiotherapy for locally advanced non-metastatic pancreatic cancer not-yet-due
Other 2013-005336-23 Outcome After Selective Early Treatment for Closure of Patent Ductus Arteriosus in Pre-term Babies not-yet-due
Reported results 2014-000126-38 Towards improved meningococcal vaccines: a randomised, descriptive, open label study exploring the relationship between gene expression signatures with reactogenicity and immunogenicity following vacc... 2018-04-27 due-trials
Exempt, with results 2014-000463-40 A Sequential Phase I study of MEK1/2 inhibitors PD-0325901 or Binimetinib combined with cMET inhibitor Crizotinib in RAS Mutant and RAS Wild Type(with aberrant c-MET) Colorectal Cancer 2018-12-03 not-yet-due
Reported results Terminated 2014-001301-40 A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of Concomitant Administration of the Combination Malaria Vaccine Candidate Regimen of RTS,S/AS01¬B + ChAd63 and MV... 2015-10-16 due-trials
Reported results 2014-002699-98 OxLith: Exploration of the short-term physical and psychological effects of lithium in mood instability 2018-03-13 due-trials
Other 2014-002978-36 Vaccines Against Salmonella Typhi: a phase IIb, single centre, observer-blind, randomised controlled trial to assess the immunogenicity and protective efficacy of Vi conjugated (Vi-TCV) and unconjugat... not-yet-due
Other 2014-002997-35 A phase III multi-centre randomised, double blind, placebo controlled trial to assess the role of intravenous immunoglobulin in the management of children with encephalitis (The IgNiTE study) not-yet-due
Reported results Terminated 2014-003237-25 A blinded randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants 2018-03-15 due-trials
Reported results 2014-004471-23 Antivirals for influenza -Like Illness? An rCt of Clinical and Cost effectiveness in primary CarE. Antiviral behandling mot influensaliknande sjukdom? En RCT för att bedöma klinisk effekt och kostn... 2018-05-09 due-trials
Other 2015-000323-86 A randomised, parallel group, double blind, placebo controlled, add on clinical trial to investigate whether the lithium mimetic, ebselen, can reduce symptoms of hypomania and mania in bipolar patient... not-yet-due
Other 2015-000817-32 Assessment of post booster antibody responses in UK infants given a reduced priming schedule of meningococcal serogroup B and 13 valent pneumococcal conjugate vaccines not-yet-due
Reported results 2015-000872-89 ANODE: a randomised controlled trial of prophylactic ANtibiotics to investigate the prevention of infection following Operative vaginal DElivery. 2018-11-12 due-trials
Other 2015-001321-17 A randomised control trial of 5-Aminolevulinic Acid in combination with Sodium Ferrous Citrate to Enhance Cardioprotection in Adults undergoing Cardiac Surgery not-yet-due
Other 2015-001383-18 An open label Phase 2 clinical trial of retinal gene therapy for choroideremia using an adeno-associated viral vector (AAV2) encoding Rab-escort protein 1 (REP1) not-yet-due
Reported results 2015-001468-21 Inhaled furosemide for dyspnoea relief in advanced heart failure 2017-10-02 due-trials
Reported results 2015-001648-12 A phase II, open label trial to describe immune and transcriptional responses to MF59 adjuvanted trivalent influenza vaccine (ATIV) in 13-24 month healthy children and adults 18-65 years 2018-09-24 due-trials
Other 2015-001780-40 A multi-centre, double blind, randomised, placebo-controlled, parallel group, phase II trial to determine the efficacy of intra-nodular injection of anti-TNF to control disease progression in early Du... not-yet-due
Reported results 2015-002837-23 Low-dose Glibenclamide in Type 2 Diabetes Mellitus - Part A (LEGEND-A) 2017-03-09 due-trials
Other 2015-003542-68 The effect of single-dose losartan on the basic effects of cognitive-behaviour therapy for panic disorder - a randomized double blind placebo-controlled trial not-yet-due
Exempt, with results 2015-003965-27 A phase I dose escalation safety study combining the ATR inhibitor M6620 with chemoradiotherapy in oesophageal cancer & other sold cancers using time to event continual reassessment method not-yet-due
Other 2016-000559-28 Randomised phase II Trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum–resistant ovarian cancer not-yet-due
Reported results 2016-001265-92 A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of adjuvanted R21 at different doses and the Combination Malaria Vaccine Candidate Regimen of adjuvanted R21 + ChA... 2017-12-21 due-trials
Reported results 2016-001718-31 A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium falciparum malaria vaccine candidate RH5.1/AS01 2019-06-27 due-trials
Reported results Terminated 2016-002045-36 Lifestyle induced weight loss and Liraglutide in the treatment of non-alcoholic steatohepatitis (NASH) 2019-04-20 due-trials
Exempt, with results 2016-002267-33 A parallel group phase I/II marker lesion study to assess the safety, tolerability and efficacy of intravenous or intravesical pembrolizumab in intermediate risk recurrent non-muscle invasive bladder ... 2019-06-26 not-yet-due
Other 2016-002656-24 A randomised placebo-controlled clinical trial of fenofibrate to prevent progression of non-proliferative retinopathy in diabetes not-yet-due
Reported results 2016-002991-28 GRASP: Getting it Right: Addressing Shoulder Pain. Clinical and cost effectiveness of progressive exercise compared to best practice advice, with or without corticosteroid injection, for the treatmen... 2020-06-12 due-trials
Reported results 2016-003060-40 Targeting Iatrogenic Cushing’s Syndrome with 11β-hydroxysteroid dehydrogenase type 1 Inhibition 2019-02-27 due-trials
Other 2016-003109-32 An investigation of Levetiracetam in Alzheimer’s Disease (ILiAD): a proof of concept study not-yet-due
Reported results 2016-003678-42 Immunological effects of an acellular pertussis booster vaccination in children, young adults and elderly with different immunisation background. An international study in Finland, the Netherlands and... 2020-01-14 due-trials
Other 2016-004236-38 OPtimising Treatment for MIld Systolic hypertension in the Elderly: a randomised controlled trial not-yet-due
Reported results 2017-000124-95 Randomised Controlled Crossover Trial of Inhaled Furosemide for Dyspnoea Relief in Advanced Heart Failure 2019-11-02 due-trials
Exempt, with results 2017-001049-28 A Phase I/II Study to assess the safety, immunogenicity and protective efficacy of novel malaria vaccine candidates ChAdOx1 LS2 and MVA LS2 in healthy UK adults 2017-12-20 not-yet-due
Exempt, with results 2017-001075-23 A Phase I/IIa Sporozoite Challenge Study to assess the safety, immunogenicity and protective efficacy of intravenous boosting with malaria vaccine candidates ChAd63 and MVA encoding ME-TRAP 2019-06-10 not-yet-due
Other 2017-001421-41 The TWO Study: Transplantation Without Over-immunosuppression. A Phase IIb Trial of Regulatory T Cells in Renal Transplantation. not-yet-due
Reported results 2017-001586-24 Delivering personalised care in the management of exacerbations of chronic obstructive pulmonary disease: A multi-centre randomised clinical trial 2020-10-09 due-trials
Other 2017-001992-22 Phase II open label randomised safety and efficacy study of the viral vectored ChAd-MVA 5T4 vaccine in combination with PD-1 checkpoint blockade in low- or intermediate-risk localized or locally advan... not-yet-due
Other 2017-002126-20 Interleukin-2 therapy of Autoimmunity in Diabetes: ITAD not-yet-due
Other 2017-002189-39 A randomised placebo-controlled trial to assess the effect of melatonin on circadian sleep-wake disturbances in ocular disease. not-yet-due
Other 2017-002798-21 A multi-centre, blinded, randomised, placebo-controlled trial assessing the clinical and cost effectiveness of a 12 month course of oral alendronate (70mg weekly) in patients presenting with avascular... not-yet-due
Other 2017-003911-21 Dapagliflozin during exercise for the prevention of hypoglycaemia in Type 1 diabetes not-yet-due
Other 2017-004542-24 Clinical effectiveness of standard step up care (methotrexate) compared to early combination DMARD therapy with standard step up care compared to early use of TNF inhibitors with standard step up care... not-yet-due
Other 2017-004609-42 Evaluating the effect of immunisation with group B meningococcal vaccines on meningococcal carriage not-yet-due
Other 2017-004610-26 Evaluating the Long Term Immunogenicity of adenoviral and MVA vectored Ebola vaccine schedules and response to late boosting with AD26.ZEBOV vaccine: an open-label clinical trial not-yet-due
Reported results 2017-004732-11 Preventing meningitis in young people after infant immunisation: effect of a single meningococcal 4CMenB vaccine booster over 10 years of age 2020-09-28 due-trials
Other 2017-005066-22 HPS-4/TIMI 65/ORION-4: A double-blind randomized placebo-controlled trial assessing the effects of inclisiran on clinical outcomes among people with atherosclerotic cardiovascular disease not-yet-due
Other 2018-000065-37 Randomised controlled trial of nasal decongestants versus placebo to prolong treatment free periods from continuous positive airway pressure therapy in mild to moderate obstructive sleep apnoea not-yet-due
Other 2018-000095-15 A Phase II, Open Label, Randomised Study of Ipilimumab With Temozolomide Versus Temozolomide Alone after Surgery and Chemoradiotherapy in Patients with Recently Diagnosed Glioblastoma (IPI-GLIO) not-yet-due
Reported results 2018-000767-91 INtravenous Iron to Treat Anaemia in CriTical Care Survivors (INTACT): a feasibility study 2020-03-16 due-trials
Other 2018-001085-42 Clinical effectiveness of symptomatic therapy compared to standard step up care for the treatment of low impact psoriatic oligoarthritis: a 2 arm parallel group feasibility study. not-yet-due
Other 2018-001915-63 A randomised controlled pilot trial of the use of GnRH-antagonist pituitary suppression during medicated frozen-thawed embryo transfer (FET) cycles not-yet-due
Other 2018-002366-39 A pilot trial of intravenous iron for the treatment of iron deficiency in adult patients with cystic fibrosis not-yet-due
Other 2018-003451-38 Immunogenicity and reactogenicity of concomitantly administered hexavalent and Group B meningococcal vaccines in infancy. not-yet-due
Exempt, with results 2018-004149-17 A randomised, placebo-controlled, single-blind study to characterise the biomarker effects of the CSF-1 receptor antagonist JNJ-40346527 in participants with mild cognitive impairment not-yet-due
Other 2018-004391-34 A Phase I/IIa Sporozoite Challenge Study to assess the safety, immunogenicity and protective efficacy of adjuvanted R21, administered in different dose schedules in healthy UK volunteers. not-yet-due
Other 2018-004401-79 The use of Benralizumab, an interleukin-5 receptor-α monoclonal antibody as treatment of acute exacerbations of airways disease not-yet-due
Other 2019-000643-27 A Phase IIa challenge study to assess efficacy of the Plasmodium vivax malaria vaccine candidates ChAd63 PvDBP and MVA PvDBP in healthy adults living in the UK not-yet-due
Other 2019-001023-13 PAX-D: Randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression not-yet-due
Other 2019-001789-13 A randomised, open label study, exploring the differences in immunogenicity and reactogenicity of infants after immunisation with either an acellular (aP) or whole cell pertussis (wP) vaccine not-yet-due
Exempt, with results 2019-002872-14 A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium vivax malaria vaccine candidate PvDBPII in Matrix M1 in healthy adults living in the UK not-yet-due
Other 2020-001072-15 A phase I/II study to determine efficacy, safety and immunogenicity of the candidate Coronavirus Disease (COVID-19) vaccine ChAdOx1 nCoV-19 in UK healthy adult volunteers not-yet-due
Other 2020-001113-21 Randomised Evaluation of COVID-19 Therapy (RECOVERY) not-yet-due
Other 2020-001135-27 Pre-operative 5-Aminolevulinic acid to activate haem oxygenase to improve outcomes in cardiac surgery: A dose finding study not-yet-due
Other 2020-001209-22 Platform Randomised trial of INterventions against COVID-19 In older peoPLE not-yet-due
Other 2020-001228-32 A phase 2/3 study to determine the efficacy, safety and immunogenicity of the candidate Coronavirus Disease (COVID-19) vaccine ChAdOx1 nCoV-19 not-yet-due
Ongoing, reported early 2020-001441-39 Chloroquine/ hydroxychloroquine prevention of coronavirus disease (COVID-19) in the healthcare setting; a randomised, placebo-controlled prophylaxis study (COPCOV) not-yet-due
Other 2020-001740-26 A multi-centre open-label two-arm randomised superiority clinical trial of Azithromycin versus usual care In Ambulatory COVID-19 (ATOMIC2) not-yet-due
Other 2020-001889-10 Use of inhaled corticosteroids as treatment of early COVID-19 infection to prevent clinical deterioration and hospitalisation not-yet-due
Other 2020-002567-57 To determine whether administration of almitrine bismesylate can ameliorate hypoxaemia in Covid-19 and augment effectiveness of supplementary oxygen therapy and respiratory support not-yet-due
Other 2020-003628-18 Adalimumab in COVID-19 to present respiratory failure in community care (AVID-CC): A randomised controlled trial not-yet-due