These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Ongoing 2006-002081-19 The Effects of EGFR Inhibition on Pulmonary Arterial Hypertension Associated with Systemic Sclerosis A phase II open-label safety and efficacy study. not-yet-due
Ongoing 2006-002392-40 First international trial for diagnosia nd treatment of langerhans cell histiocytosis in adults not-yet-due
Exempt 2006-003149-17 Phase I study of concurrent with involved-field thoracic radiotherapy for inoperable non-squamous cell lung cancer, followed by both concurrent and maintenance Bevacizumab not-yet-due
Not reported 2006-003483-59 PRESERVE TRIAL: Pancreatic beta-cell dysfunction REStorEd by Rosiglitazone and Valsartan Effects; A 52-week randomized controlled factorial study in subjects with impaired fasting glucose and/or impai... 2009-11-03 due-trials
Ongoing 2006-006058-83 Phase II randomized trial of combination therapy of paclitaxel and bevacizumab versus paclitaxel, capecitabine and bevacizumab as first-line treatment for locally recurrent or metastatic breast cancer... not-yet-due
Exempt 2007-001104-21 A PHASE I/II TRIAL OF A CONDITIONALLY REPLICATION-COMPETENT ADENOVIRUS (DELTA-24-RGD) ADMINISTERED BY CONVECTION ENHANCED DELIVERY IN PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME not-yet-due
Exempt 2007-002962-37 Phase I/II study of dalteparin, a low molecular weight heparin (LMWH), in combination with Sunitinib (SU11248), an oral, selective multitargeted tyrosine kinase inhibitor, as first line treatment, in ... 2015-10-14 not-yet-due
Reported results 2007-003187-22 Clinical trials for adults HD18 for advanced stages Treatment optimization trial in the first-line treatment of advanced stage Hodgkin lymphoma; treatment stratification by means of FDG-PET Therapi... 2019-07-18 due-trials
Ongoing 2007-004335-39 A randomized phase II trial of docetaxel plus carboplatin versus docetaxel in hormone refractory prostate cancer patients who have progressed after response to prior docetaxel chemotherapy: RECARDO ST... not-yet-due
Listed as ongoing, but also has a completion date and reported results 2007-004474-24 HD 16 for early stages: treatment optimization trial in the first-line treatment of early stage Hodgkin lymphoma; treatment stratification by means of FDG-PET. 2020-12-29 bad-data
Ongoing 2007-004625-14 A phase II study of erlotinib and sorafenib in patients with locally advanced and/or metastatic (stage IIIB or IV) Non-Small cell lung cancer (NSCLC) who have not received prior chemotherapy not-yet-due
Exempt 2007-005164-27 Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/ Interstitial Cystitis not-yet-due
Listed as ongoing, but also has a completion date 2007-005306-49 A Phase II Study Of Vorinostat (MK-0683) In Patients With Polycythaemia Vera And Essential Thrombocythaemia 2012-08-15 bad-data
Reported results 2007-005920-34 HD17 for Intermediate Stage Hodgkin Lymphoma - Treatment Optimization Trial in the First-Line Treatment of intermediate Stage Hodgkin lymhoma; Therapy stratification by means of FDG-PET 2020-03-21 due-trials
Ongoing 2007-007075-16 The effect of peroxisome proliferator activator receptor γ agonist pre-treatment on pegylated interferon-α2a and ribavirin efficacy in hepatitis C patients, previously resistant to treatment with pegy... not-yet-due
Ongoing 2008-005015-17 Effect of N-acetylcysteine on thiopurine related hepatotoxicity in IBD patients not-yet-due
Ongoing 2008-005325-10 The effect of exenatide compared to insulin glargine on cardiac function and metabolism in type 2 diabetic patients with congestive heart failure (NYHA II): a randomized-controlled trial not-yet-due
Not reported 2009-010758-36 Pyridostigmine: using a cholinesterase inhibitor to activate the cholinergic anti-inflammatory pathway in patients with CRPS-1 2011-04-28 due-trials
Ongoing 2009-011753-41 Pain treatment of newborns: paracetamol rectal versus intraveneous administration, an open randomised clinical trial. not-yet-due
Ongoing 2009-012944-17 Effect of a single dose of 14.8 MBq/kg (0.4 mCi/kg) 90Y-ibritumomab tiuxetan (“Zevalin”) following first-line R-CVP therapy in patients with follicular lymphoma on conversion rate assessed by FDG-PET ... not-yet-due
Ongoing 2009-013403-55 Early recognition and optimal treatment of delirium in patients with advanced cancer. not-yet-due
Ongoing 2009-014272-21 Effect of additional treatment with exenatide in patients with an acute myocardial infarction: the EXAMI trial) not-yet-due
Ongoing 2009-016080-11 A COMPREHENSIVE AND TARGETED THERAPY APPROACH IN PEDIATRIC MALIGNANT PONTINE GLIOMAS not-yet-due
Exempt Terminated 2010-018327-26 Chemoradiation with gemcitabine in combination with panitumumab for patients with locally advanced pancreatic cancer. not-yet-due
Ongoing 2010-019252-41 DALI dosing study of Vitamin D in obese pregnant women not-yet-due
Ongoing 2010-019891-54 Effects of oral corticosteroids and DMSO on inflammatory signs and symptoms in Complex Regional Pain Syndrome type 1 not-yet-due
Ongoing 2010-019982-27 Targeted therapy selection based on tumor tissue kinase activity profiles for patients with advanced solid malignancies, an exploratory study not-yet-due
Ongoing 2010-020397-42 The efficacy of an antigenic marker lesion for the therapeutic effect in patients with multiple, Ta/T1, G1/G2, non-muscle invasive bladder cancer (NMIBC) treated with TUR followed by IL-2 instillation not-yet-due
Ongoing 2010-020424-21 Betablocker Therapy in Pulmonary Arterial Hypertension not-yet-due
Completed, but no date Terminated 2010-021797-10 A phase II randomized multicenter study on efficacy and safety of cultured autologous skin (Tiscover®) and acellular dermal matrix (AS210) in chronic (arterio-)venous ulcers bad-data
Completed, but no date 2010-021943-41 Treatment optimization of cetuximab in patients with metastatic colorectal cancer based on tumour uptake of 89Zr-labeled cetuximab assessed by PET bad-data
Ongoing 2010-023233-30 ‘Intravenous iron treatment in iron deficient patients with pulmonary arterial hypertension' not-yet-due
Exempt 2010-023577-20 Revlimid, Endoxan, Prednisone Evaluation After prior revlimid Treatment (REPEAT): A phase 1 and phase 2 study of lenalidomide (Revlimid) in combination with cyclophosphamide (endoxan) and prednisone (... not-yet-due
Exempt Terminated 2010-024515-13 Phase 1-2 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer. not-yet-due
Listed as ongoing, but also has a completion date 2011-000440-22 MULTICENTER TRIAL ESTIMATING THE PERSISTANCE OF MOLECULAR REMISSION IN CHRONIC MYELOID LEUKAEMIA AFTER STOPPING TKI 2017-11-20 bad-data
Ongoing 2011-000538-12 An exploratory open-label PET-observer-blinded pilot study to evaluate the effect of 3 and 12 months treatment with Aliskeren-based versus amlodipin-based antihypertensive treatment in patients with a... not-yet-due
Ongoing 2011-000753-24 Central effects of endogenous GLP-1 and the GLP-1 analog liraglutide on brain satiety and reward circuits and feeding behavior in diabetes. not-yet-due
Ongoing 2011-001251-37 Exploring alternative wound care treatment for percutanous gastrostomy site infection: a prospective, randomized, open, blinded end-point (PROBE) design. not-yet-due
Not reported 2011-002211-28 Perioperative selective decontamination of the digestive tract (SDD) in elective colorectal cancer patients: a multicenter randomized clinical trial 2020-03-25 due-trials
Ongoing 2011-003325-10 A randomized controlled trail on the effects of periconceptional and prenatal folic acid supplementation on congenital anomalies and preterm birth not-yet-due
Ongoing 2011-003570-89 The effect of interferon beta-1a treatment on functional adaptation in Multiple Sclerosis (MS) Het effect van interferon beta-1a behandeling op functionele adaptatie in Muliple Sclerose (MS not-yet-due
Completed, but no date Terminated 2011-004446-17 Metoclopramide, dexamethasone or Aloxi for the prevention of delayed chemotherapy-induced nausea and vomiting in moderately emetogenic non-AC-based chemotherapy: the MEDEA trial bad-data
Completed, but no date, and reported results 2011-004495-12 Antibiotic treatment alone for children with acute appendicitis; a prospective cohort study part of the Antibiotic versus Primary Appendectomy for Children with acute appendicitis; the APAC trial. bad-data
Ongoing 2011-004683-30 A phase II study of sorafenib and metformin in patients with locally advanced and/or metastatic non-smal cell lung cancer (NSCLC) with a K-Ras mutation not-yet-due
Completed, but no date 2011-004762-15 Early pharmacological intervention to prevent delirium: HAlopeRidol PrOphylaxis in Older emergency department patieNts. The HARPOON study Preventie van delirium door vroegtijdige pharmacologische i... bad-data
Ongoing 2011-005003-32 A randomized multicenter clinical trial for patients with multi-organ, colorectal cancer metastases comparing the combination of chemotherapy and maximal tumor debulking versus chemotherapy alone. not-yet-due
Ongoing 2011-005160-23 Hismys study. Misoprostol for cervical priming prior to hysteroscopy in postmenopausal and nulliparous premenopausal women; a multi-centre randomised placebo controlled trial not-yet-due
Ongoing 2011-005165-21 De-ESCALaTE HPV: Determination of Epidermal growth factor receptor-inhibitor (cetuximab) versus Standard Chemotherapy (cisplatin) early And Late Toxicity Events in Human Papillomavirus-positive oropha... not-yet-due
Ongoing 2011-006009-85 Prediction of response to kinase inhibitors based on protein phosphorylation profiles in tumor tissue from advanced renal cell cancer patients not-yet-due
Ongoing 2012-000345-12 A phase II study of gefitinib and fulvestrant in patients with advanced, EGFR mutated non-small cell lung cancer pretreated with reversible EGFR tyrosine kinase inhibitors Een Fase II studie van ge... not-yet-due
Ongoing 2012-000850-75 Clinical evaluation of the efficacy of methylnaltrexone in resolving constipation induced by different opioid subtypes combined with laboratory analysis of immunomodulatory and antiangiogenic effects ... not-yet-due
Completed, but no date Terminated 2012-001530-34 Varenicline, a partial nicotinic receptor agonist for the treatment of Excessive Daytime Sleepiness in Parkinson’s Disease: a placebo-controlled cross-over study bad-data
Ongoing 2012-001541-40 Effect of Carbon Dioxide Enriched Ambient Air on Pharmacokinetics and Deposition In Bronchiectasis Patients Using Tobramycin Inhalation: A proof of concept study. Het effect van koolstofdioxide ve... not-yet-due
Ongoing 2012-001597-29 Tumor uptake of 89Zirconium-ofatumumab and 89Zirconium-rituximab in diffuse large B cell lymphoma patients Tumor opname van 89Zirconium-ofatumumab en 89Zirconium-rituximab bij patienten met een dif... not-yet-due
Ongoing 2012-001599-12 The clinical value of amyloid imaging with [18F]-AV45 in a population of memory clinic patients not-yet-due
Completed, but no date 2012-002303-18 The Dutch Flutemetamol in Young Dementia Study De Nederlandse Flutemetamol in Vroege Dementie Study bad-data
Not reported Terminated 2012-002891-15 Phase II study of sunitinib rechallenge in patients with metastatic renal cell carcinoma. 2017-04-20 due-trials
Ongoing 2012-003141-16 Efficacy and feasibility of first-line treatment with risk-adapted dose-adjusted EPOCH-R (DA-EPOCH-R) in patients with Burkitt lymphoma. A phase II clinical trial. not-yet-due
Ongoing 2012-003359-12 The effect of a high and low protamine-to-heparin dosing on perioperative hemostasis: a randomized clinical trial. Het effect van een hoge en lage protamine:heparine doseringsratio op perioperatie... not-yet-due
Ongoing 2012-003616-31 Uptake and biodistribution of 89Zirconium-labeled ipilimumab in ipilimumab treated patients with metastatic melanoma Opname en biodistributie van 89Zirconium-gelabeld ipilimumab in patienten met ge... not-yet-due
Completed, but no date 2012-003981-42 Estrogen receptor and androgen receptor imaging in metastatic breast cancer patients bad-data
Ongoing 2012-004321-25 A phase II, single arm, multicenter study of nilotinib in combination with pegylated interferon α2b in patients with suboptimal molecular response or stable detectable molecular residual disease after... not-yet-due
Ongoing 2012-004961-42 Measurement of tumor kinase inhibitor concentrations using PET imaging in patients with advanced solid malignancies Het meten van concentraties kinaseremmer in tumorlesies bij patienten met vergevo... not-yet-due
Ongoing 2012-005066-36 Effect of Growth Hormone replacement therapy on cardiovascular risk factors in adult patients with severe growth hormone deficiency: association with IGF-I concentration not-yet-due
Completed, but no date 2012-005332-29 Prevention of depression and poor physical function in older persons with vitamin D supplementation Preventie van depressie en matig lichamelijk functioneren bij ouderen met vitamine D-suppletie bad-data
Ongoing 2013-000238-37 Treatment guided by detection of Minimal Residual Disease after allogeneic stem cell transplantation in Acute Myeloid Leukaemia not-yet-due
Ongoing, reported early 2013-000789-13 DALI: Vitamin D And Lifestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention - A European multicentre, randomised trial not-yet-due
Not reported Terminated 2013-001722-25 Cholinesterase inhibitors to slow progression of visual hallucinations in Parkinson’s disease: a multi-center placebo-controlled trial (CHEVAL) 2018-09-27 due-trials
Ongoing 2013-001743-31 The cardiovascular effects of hyperoxia during and shortly after CABG surgery not-yet-due
Completed, report not yet due Terminated 2013-002023-41 Image guided treatment optimalization with cetuximab for patients with metastatic colorectal cancer: IMPACT - CRC Optimalisatie van de behandeling van uitgezaaide dikke darmkanker met cetuximab mid... 2021-01-07 not-yet-due
Ongoing 2013-002563-25 Pilot study to determine the effect of fractionated radiotherapy on expression of pro-angiogenic factors in oeshophagus carcinoma Een pilot studie om het effect te onderzoeken van gefractioneerde r... not-yet-due
Exempt, with results Terminated 2013-002663-25 A phase I- IIa open-label clinical trial, evaluating the therapeutic vaccine hVEGF26-104/RFASE in patients with advanced solid tumors Een fase I-IIa klinische studie naar het therapeutisch vaccin h... not-yet-due
Not reported Terminated 2013-002670-40 Noninvasive Imaging of Vulnerable Inflammatory Coronary Plaque using Cardiac PET/CT in Humans: a feasibility study Onderzoek naar het gebruik van verschillende PET-tracers voor het vaststellen van ... 2018-11-15 due-trials
Ongoing 2013-003354-24 Influence of exogenous growth hormone administration on circulating levels of Klotho in healthy and CKD subjects not-yet-due
Not reported 2013-003658-26 Treat-to-target strategy for early RA patients in usual clinical practice: The COBRA Cohort Study 2018-12-18 due-trials
Ongoing 2013-003733-15 The Dutch CSF and PET Biomarker Concordance of Alzheimer’s Disease pathology study De Nederlandse CSF en PET Biomarker Concordantie van Alzheimer pathologie studie not-yet-due
Not reported 2013-003949-41 Role of different phosphate binders on absorption of vitamin K, metabolism of matrix γ-carboxy-glutamaat (Gla) proteïne (MGP). Rol van verschillende fosfaatbinders t.a.v. absorptie van vitamine K, ... 2018-10-01 due-trials
Ongoing 2013-004120-11 PI3K pathway analysis in tumor tissue and circulating DNA to obtain further insight in the efficacy of everolimus when combined with exemestane. A side-study protocol attached to standard treatment wi... not-yet-due
Not reported 2013-004635-69 A phase II study of obinutuzumab monotherapy in rituximab-refractory follicular lymphoma Obinutuzumab monotherapie voor rituximab-refractair folliculair lymfoom 2019-10-25 due-trials
Ongoing 2014-000047-33 The effect of high-resistance muscle strength training and vitamin D supplementation in persons with knee osteoarthritis Het effect van hoog-intensieve spierkrachttraining en vitamine D suppletie b... not-yet-due
Ongoing 2014-000219-15 Amyloid pathology in cognitively normal elderly subjects Amyloid pathologie in cognitief normale ouderen not-yet-due
Ongoing 2014-000304-96 Sentinel lymph node identification in colon cancer using a radioactive and fluorescent tracer not-yet-due
Ongoing 2014-000562-21 Amyloid-PET as a diagnostic marker in daily practice. Amyloid-PET als een diagnostische marker in de dagelijkse praktijk. not-yet-due
Ongoing 2014-001012-19 Effects of fingolimod on functional brain adaptation and clinical measures in multiple sclerosis Het effect van fingolimod op functionele breinadaptatie en klinische maten in multiple sclerose not-yet-due
Not reported 2014-001546-25 Short versus extended antibiotic treatment with a carbapenem for high-risk febrile neutropenia in hematology patients with Fever of Unknown Origin: a randomized multicenter open-label non-inferiority ... 2019-08-05 due-trials
Ongoing 2014-001561-27 Vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia: comparing one-hour infusions with bolus injections (the VINCA-study) Vincristine-geïnduceerde perifere neuro... not-yet-due
Not reported 2014-002178-35 A phase 4, monocenter, randomized, open label, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 8-week treatment with the glucagon-like peptide-1 receptor ... 2019-08-14 due-trials
Ongoing 2014-002514-23 Reduction Of Microvascular Injury Utilizing Sonolysis not-yet-due
Not reported 2014-002547-17 Grey matter microglial imaging with [18F]DPA-714 in progressive MS patients Beeldvorming van microglia in de grijze stof met [18F]DPA-714 bij progressieve MS patiënten 2016-01-21 due-trials
Completed, but no date, and reported results 2014-002832-15 Ulipristal versus Gonadotropin-releasing hormone agonists prior to laparoscopic myomectomy: a double blind randomized controlled trial Ulipristal versus Gonadotropine-releasing hormoon agonists voo... bad-data
Ongoing 2014-002928-27 Observing Platelet Activability in a Once daily vs. a More frequent Aspirin intake regimen not-yet-due
Ongoing 2014-003385-24 The Recall-study: Rivastigmine for ECT-induced Cognitive Adverse effects in Late Life Depression: a multicenter, randomized, double-blind, placebo-controlled, crossover trial De Recall studie: Riv... not-yet-due
Ongoing 2014-003468-19 The effects of hyperoxia on organ dysfunction and outcome in critically ill patients with SIRS Het effect van hyperoxie op orgaan dysfunctie en overleving in Intensive Care patienten met SIRS not-yet-due
Ongoing 2014-003469-10 The application of contrast-enhanced ultrasound to facilitate thrombolysis in patients with acute peripheral arterial occlusions. not-yet-due
Ongoing 2014-003680-38 Pharmacokinetics of two different high dose regimes of intravenous vitamin C in critically ill patients Farmacokinetiek van twee verschillende hoge doseerregimes van intraveneus vitamine C bij IC p... not-yet-due
Completed, but no date 2014-003932-38 Advanced imaging in laparoscopic HIPEC for peritoneal carcinomatosis of colorectal orgin to improve cytoreduction; a feasibility study bad-data
Ongoing 2014-004739-38 Follow-up of the FRUIT-RCT; aspirin resistance and cardiovascular risk factors in women after recurrent hypertensive disorders in pregnancy not-yet-due
Listed as ongoing, but also has a completion date 2014-005363-33 Reducing Micro Vascular dysfunction In revascularized STEMI patients by off-target properties of ticagrelor 2019-04-09 bad-data
Ongoing 2015-000644-42 Laparoscopic advanced Imaging Techniques in Endometriosis therapy: LITE-study. A pilot trial. not-yet-due
Completed, report not yet due 2015-002729-21 The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study Comparing the cost-effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rh... 2021-01-29 not-yet-due
Not reported 2015-003220-31 Low dose aspirin in the Prevention of Recurrent Spontaneous Preterm Labour – the APRIL study 2020-03-27 due-trials
Exempt Terminated 2015-003554-41 A phase I/II “minor histocompatibility antigen UTA2-1 loaded, PD-L silenced Dendritic cell vaccination trial after allogeneic Stem Cell Transplantation to improve the safety and efficacy of Donor Lym... not-yet-due
Ongoing 2015-003705-42 Longitudinal imaging of tau accumulation in the preclinical stages of AD Longitudinale beeldvorming van de accumulatie van tau in de preklinische stadia van de ziekte van Alzheimer not-yet-due
Ongoing 2015-003818-24 A phase 4, monocenter, randomized, double-blind, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 12-week treatment with the sodium-glucose linked transpor... not-yet-due
Exempt 2015-003862-10 A phase 1 and phase 2 study of daratumumab in combination with all-trans retinoic acid in relapsed/refractory multiple myeloma not-yet-due
Not reported 2015-004230-10 Validating in vivo quantification of tau with [18F]AV-1451 PET Het valideren van in vivo quantificatie van tau met [18F]AV-1451 PET 2018-11-08 due-trials
Ongoing 2015-004260-10 89Zirconium-labeled pembrolizumab as predictive imaging biomarker of response and toxicity in pembrolizumab treated patients with non-small-cell lung cancer – a feasibility study 89Zirconium gelabe... not-yet-due
Ongoing 2015-004760-11 89Zirconium-labeled nivolumab and 18F-labeled anti-PD-L1 as predictive imaging biomarkers of response and toxicity in nivolumab treated patients with non-small-cell lung cancer – a feasibility study ... not-yet-due
Not reported 2015-004937-29 Towards early identification of response to CABAZItaxel in patients with metastatic castration-resistant prostate cancer: potential of 18F-Choline PET-CT (CABAZIPET). Vroegtijdig identificeren va... 2019-05-01 due-trials
Ongoing 2015-004998-33 Multicenter prospective trial after first or second unsuccessful treatment discontinuation in chronic myeloid leukemia estimating the efficacy of nilotinib in inducing the persistence of molecular rem... not-yet-due
Ongoing 2015-005765-23 Companion biomarker development for MEDI4736 treated non-small-cell lung cancer patients using 89Zirconium-labeled MEDI4736 – a feasibility study Biomarker ontwikkeling voor MEDI4736 in de behandel... not-yet-due
Ongoing 2015-005811-34 Pregnancy reLated Acute hyperTension INtervention Action: a randomized trial comparing labetalol and nicardipine in women with acute hypertension in pregnancy (Platina-trial) not-yet-due
Ongoing 2016-000345-31 Towards personalized dosing of natalizumab in multiple sclerosis Op weg naar een gepersonaliseerde behandeling met natalizumab in multiple sclerose not-yet-due
Ongoing 2016-001353-41 Oxygenation of Affected Limbs in CRPS-I Patients not-yet-due
Ongoing 2016-001797-15 A phase II/III study of high-dose, intermittent sunitinib in patients with recurrent glioblastoma multiforme Een fase II/III studie met intermitterend, hoge dosis sunitinib bij patiënten met een re... not-yet-due
Completed, but no date 2016-002342-23 The cardiovascular dose-response to supplemental oxygen in healthy volunteers bad-data
Not reported Terminated 2016-002635-15 Study to Identify Factors associated with Resilience to Clinical Dementia at Old Age Studie naar de beschermende factoren voor dementie bij mensen boven de 90 jaar 2018-10-02 due-trials
Ongoing 2016-003819-36 Combining SBRT and pembrolizumab in early stage non-small cellular lungcancer patients planned for surgery: exploring safety and immunological proof of principle. De combinatie van stereotactische... not-yet-due
Completed, report not yet due Terminated 2016-004303-32 ASsesment of Platelet function and Inhibition in patients Recovering from severe INfection 2021-03-18 not-yet-due
Ongoing 2016-004545-91 Continuous use of Oral contraceptives as an alternative for long term Pituitary down-regulation with GnRH agonist prior to IVF/ICSI in Endometriosis patients: a randomised controlled trial (COPIE tria... not-yet-due
Reported results Terminated 2017-000137-31 Pulmonary Hypertension REversal in Clusters of Patients With Identical Pathobiological Substrates. 6-Mercaptopurine Proof-of-Concept Trial 2019-07-01 due-trials
Ongoing 2017-000169-60 A phase 2 study of nivolumab combined with daratumumab with or without low dose cyclophosphamide in relapsed/refractory multiple myeloma not-yet-due
Ongoing 2017-000364-15 A randomized phase II/III study of pulsatile high-dose sunitinib versus TAS-102 in patients with metastatic colorectal carcinoma (mCRC). Gerandomiseerde fase II-III studie tussen sunitinib versus T... not-yet-due
Ongoing 2017-000841-28 Combined effects of SGLT2 inhibition and GLP-1 receptor agonism on food intake, body weight and central satiety and reward circuits in obese T2DM patients not-yet-due
Ongoing 2017-001438-25 A Study to Explore the Safety, Tolerability, Pharmacokinetic Profile, and Potential Efficacy of Guanabenz in Patients With Early Childhood Onset Vanishing White Matter (VWM) not-yet-due
Ongoing 2017-001547-12 A phase 4, monocenter, randomized, double-blind, comparator-controlled, 3-armed parallel mechanistic intervention trial to assess the effect of 8-week empagliflozin (SGLT-2 inhibitor) monotherapy, fol... not-yet-due
Ongoing 2017-001840-37 ERtugliflozin triAl in DIabetes with preserved or reduced ejeCtion FrAcTion mEchanistic evaluation in Heart Failure: "ERADICATE-HF" not-yet-due
Ongoing 2017-002022-20 The effect of inspiratory oxygen fraction on the ratio of partial arterial oxygen pressure and inspiratory oxygen fraction (PaO2/FiO2 ratio) in mechanically ventilated patients with and without mild t... not-yet-due
Ongoing 2017-002478-37 Right Dose, Right Now: Randomized Clinical Trial Meteen de juiste dosis: gerandomiseerde klinische trial not-yet-due
Ongoing 2017-002636-16 Cognitive impairment and functional reorganization in multiple sclerosis: The role of GABA and glutamate Cognitieve achteruitgang en functionele reorganisatie in multiple sclerose: de rol van GABA ... not-yet-due
Ongoing 2017-003072-31 The effects of sex hormone administration on marrow and visceral adiposity not-yet-due
Ongoing 2017-003766-27 The DREAMING study: Efficacy of low dose amitriptyline and mirtazapine for insomnia disorder: a double-blind, randomized, placebo-controlled trial in general practice not-yet-due
Exempt 2017-003860-11 11C-erlotinib brain uptake in Diffuse Intrinsic Pontine Glioma imaged by PET not-yet-due
Ongoing 2017-004318-25 Early high-dose vitamin C in post-cardiac arrest syndrome. Vroege hoge dosis intraveneuze vitamine C na reanimatie. not-yet-due
Completed, report not yet due Terminated 2017-004737-85 Alkaline Phosphatase to prevent ischemia reperfusion injury in living kidney transplantation 2020-09-10 not-yet-due
Ongoing 2017-004850-40 [18F]Fluoride PET-CT imaging for detection and monitoring of bone formation in spondyloarthritis [18F]Fluoride PET-CT beeldvorming voor het aantonen en monitoren van botformatie bij spondylartriti... not-yet-due
Ongoing 2017-005120-16 Ulipristal versus standard surgical treatment in symptomatic uterine fibroids Ulipristal versus standaard chirurgie in de behandeling van symptomatische uterine myomen not-yet-due
Ongoing 2018-000029-29 Extra energy for hearts with a genetic defect: ENERGY trial Extra energie voor harten met een genetische afwijking: ENERGY trial not-yet-due
Ongoing 2018-000748-24 Partial neuromuscular blockade to facilitate lung and diaphragm protective mechanical ventilation in ICU patients. A randomized controlled pilot study. not-yet-due
Ongoing 2018-001114-15 Positron emission tomography with macrophage targeting to select individuals at risk for rheumatoid arthritis. Positron emissie tomografie met een macrofagen tracer voor het selecteren van individ... not-yet-due
Ongoing 2018-001277-24 Microvascular Recovery in Acute MI, a single center, prospective, randomized, single blind parallel-group comparison of sonothrombolysis versus standard of care performed after (post) coronary reperfu... not-yet-due
Ongoing 2018-001678-10 Tofacitinib: salvage therapy for patients with RCDII - a pilot study Tofacitinib: laatste redmiddel voor patiënten met RCDII - een pilot study not-yet-due
Ongoing 2018-002013-35 FES (16α-[18F]-fluoro-17β-estradiol)-PET: Towards a new standard to stage clinical stage II/III and recurrent, estrogen receptor positive (ER+) breast cancer? Pilot study to compare [18F]FES-PET and [... not-yet-due
Ongoing 2018-002170-52 TrimetaziDine as a Performance-enhancING drug in Heart Failure with Preserved Ejection Fraction not-yet-due
Ongoing 2018-002277-22 AMYPAD Prognostic and Natural History Study (PNHS), an open label, prospective, multicentre, cohort study linked to the European Prevention of Alzheimer's Dementia (EPAD) Longitudinal Cohort Study (LC... not-yet-due
Ongoing 2018-002643-28 Safety and tolerability of neoadjuvant nivolumab for locally advanced resectable oral cancer, combined with [18F]BMS-986192 / [18F]-FDG PET imaging and immunomonitoring for response prediction. Ve... not-yet-due
Exempt 2018-002752-33 A phase I/II trial towards the safety and efficacy of preemptive vaccination with PD-L silenced, minor histocompatibility antigen UTA2-1 peptide-loaded Dendritic Cells after Allogeneic Stem Cell Trans... not-yet-due
Ongoing 2018-004153-24 Tubal flushing with oil-based contrast during HSG in subfertile women: Is early flushing effective and cost-effective as compared to delayed flushing? Is het verrichten van een HSG met olie contras... not-yet-due
Ongoing 2018-004192-12 Oil- based versus water-based contrast media for hysterosalpingography (HSG) in infertile women with unevaluated indications: a randomized controlled trial not-yet-due
Ongoing 2018-004429-94 [18F]PEG-folate PET-CT imaging for monitoring of therapy response in rheumatoid arthritis patients [18F]PEG-folaat PET-CT beeldvorming voor de monitoring van response op therapie bij reumatoïde art... not-yet-due
Ongoing 2018-004466-34 Tau PET imaging in cognitively normal elderly subjects: A twin approach Tau PET-beeldvorming bij cognitief normale oudere proefpersonen: een tweeling benadering not-yet-due
Ongoing 2019-000730-19 A phase 4, monocenter, prospective, randomized, placebo-controlled, double-blind, cross-over mechanistic intervention trial to assess effect of 4-week Ertugliflozin (SGLT-2 inhibitor) therapy on renal... not-yet-due
Ongoing 2019-001306-23 Reversal Of Arterial Disease by modulating Magnesium and Phosphate not-yet-due
Ongoing 2019-001518-40 Netherlands study of Optimal, PERsonalized Antidepressant use (OPERA-DISCONTINUATION) Nederlandse studie naar Optimaal gePERsonaliseerd Antidepressiva gebruik (OPERA-AFBOUW) not-yet-due
Ongoing 2019-001883-31 Microvascular Recovery using contrast Ultrasound in ST-elevation Myocardial Infarction in the ambulance (MRUSMI-Ambulance) not-yet-due
Ongoing 2019-003127-38 Efficacy of add-on high dose simvastatin on markers for disease progression in MS patients treated with ocrelizumab and natalizumab (SIMSON), a phase II clinical trial. Effectiviteit van add-on hog... not-yet-due
Ongoing 2019-003141-15 A phase 4, monocenter, randomized, double-blind, placebo-controlled, 4-armed cross-over mechanistic intervention study to assess the renal hemodynamic effect of mono- and combination therapy with empa... not-yet-due
Ongoing 2019-003324-20 Saracatinib trial TO Prevent FOP Een onderzoek ter beoordeling van de veiligheid, verdraagbaarheid en effecten op abnormale botvorming van het onderzoeksgeneesmiddel AZD0530 (saracatinib) bij patië... not-yet-due
Ongoing 2019-003454-83 Ipilimumab plus Nivolumab and ChemoRadiotherapy followed by Surgery in patients with resectable and borderline resectable T3-4N0-1 NSCLC not-yet-due
Ongoing 2019-003461-17 Pathophysiological relevance of IRON deficiency and related mitochondrial dysfunction in Heart Failure with Preserved Ejection Fraction (IRON-HFpEF) De pathofysiologische relevantie van ijzer defic... not-yet-due
Ongoing 2019-003601-10 Treatment of Skin Severity in Ichthyosis with Hyperbaric Oxygen Therapy not-yet-due
Ongoing 2019-003698-24 Patient preference-based phosphate binder therapy in haemodialysis patients: a feasibility study on patient satisfaction Haalbaarheid van een behandelstrategie gebaseerd op voorkeuren van de patien... not-yet-due
Ongoing 2019-003740-77 Personalized prediction and regulation of 5-FU exposure Gepersonaliseerd voorspelling en regulatie van 5-FU blootstelling not-yet-due
Ongoing 2019-004284-51 An exploratory study of durvalumab (MEDI4736) uptake during concurrent chemoradiotherapy in stage III NSCLC patients using 89Zr-labeled durvalumab PET not-yet-due
Ongoing 2019-004604-35 A phase 2 study of CC220 (iberdomide) combined with low-dose cyclophosphamide and dexamethasone in relapsed/refractory multiple myeloma (IberCd): ICON study Een fase 2 studie van iberdomide gecom... not-yet-due
Ongoing 2020-000165-16 A single-center, prospective, placebo-controlled, double-blind, randomized, cross-over mechanistic intervention study to investigate the effect of empagliflozin on kidney function in people with eithe... not-yet-due
Ongoing 2020-001097-29 Rescue by radiotherapy and anti-CTLA4/PD-1 after failure of anti-PD-1 therapy in metastatic NSCLC patients, a proof-of-concept study. not-yet-due
Ongoing 2020-001952-16 Progesterone for Breast Development in Trans Women; Assessment of effects and safety -a pilot trial- not-yet-due
Ongoing 2020-002079-36 TGF-β And PDL-1 inhibition with Bintrafusp alfa in Esophageal Squamous Cell carcinoma combined with chemoradiation TheRapY (TAPESTRY) TGF-β en PDL-1 blokkade met Bintrafusp alfa in plaveiselcelcarc... not-yet-due
Ongoing 2020-002185-14 18F-Prostate Specific Membrane Antigen PET-CT as a potential novel imaging modality for pancreatic cancer: A pilot study not-yet-due
Ongoing 2020-002196-35 post-trial access cohort BUmetanide for Developmental DIsorders Post trial access Bumetanide voor ontwikkelingsstoornissen not-yet-due
Ongoing 2020-002909-25 Blood-borne assessment of stromal activation in esophageal adenocarcinoma to guide tocilizumab therapy: a randomized phase II proof-of-concept study Behandeling van patiënten met resectabel oesofag... not-yet-due
Ongoing 2020-003025-37 COMBINING AFATINIB AND CONCURRENT CHEMOTHERAPY, FOLLOWED BY OSIMERTINIB AND CONCURRENT CHEMOTHERAPY, IN UNTREATED EGFR POSITIVE NSCLC TUMORS not-yet-due
Ongoing 2020-004413-13 Dual-immunotherapy and short-course medium-dose radiotherapy, followed by surgery for tumor microenvironment modification in early stage NSCLC not-yet-due
Ongoing 2020-005447-23 A randomised, double-blind, placebo-controlled study to investigate the safety and efficacy of intravenous imatinib mesilate (Impentri®) in subjects with Acute Respiratory Distress Syndrome induced by... not-yet-due
Ongoing 2021-000610-42 Dynamic and test-retest whole body [18F]FES PET imaging in patients with metastatic ER+ breast cancer. not-yet-due
Ongoing 2021-001072-41 COBRA-KAI study: COVID-19 vaccination in patients with reduced B-cell and T-cell immunity: response after vaccination of a kaleidoscopic group hematological patients, what’s the impact? COBRA-KAI s... not-yet-due
Ongoing 2021-001123-40 18F-fluciclovine PET/CT and 18F-DCFPyL PET/CT in patients with biochemical recurrence of disease after radical prostatectomy: a prospective, single-centre, single-arm, comparative imaging trial 18... not-yet-due