These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Ongoing 2006-002081-19 The Effects of EGFR Inhibition on Pulmonary Arterial Hypertension Associated with Systemic Sclerosis A phase II open-label safety and efficacy study. not-yet-due
Ongoing 2006-002392-40 First international trial for diagnosia nd treatment of langerhans cell histiocytosis in adults not-yet-due
Ongoing 2006-003149-17 Phase I study of concurrent with involved-field thoracic radiotherapy for inoperable non-squamous cell lung cancer, followed by both concurrent and maintenance Bevacizumab not-yet-due
Not reported 2006-003483-59 PRESERVE TRIAL: Pancreatic beta-cell dysfunction REStorEd by Rosiglitazone and Valsartan Effects; A 52-week randomized controlled factorial study in subjects with impaired fasting glucose and/or impai... 2009-11-03 due-trials
Ongoing 2006-006058-83 Phase II randomized trial of combination therapy of paclitaxel and bevacizumab versus paclitaxel, capecitabine and bevacizumab as first-line treatment for locally recurrent or metastatic breast cancer... not-yet-due
Ongoing 2007-001104-21 A PHASE I/II TRIAL OF A CONDITIONALLY REPLICATION-COMPETENT ADENOVIRUS (DELTA-24-RGD) ADMINISTERED BY CONVECTION ENHANCED DELIVERY IN PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME not-yet-due
Completed, report not yet due 2007-002962-37 Phase I/II study of dalteparin, a low molecular weight heparin (LMWH), in combination with Sunitinib (SU11248), an oral, selective multitargeted tyrosine kinase inhibitor, as first line treatment, in ... 2015-10-14 not-yet-due
Ongoing 2007-003187-22 Clinical trials for adults HD18 for advanced stages Treatment optimization trial in the first-line treatment of advanced stage Hodgkin lymphoma; treatment stratification by means of FDG-PET not-yet-due
Ongoing 2007-004335-39 A randomized phase II trial of docetaxel plus carboplatin versus docetaxel in hormone refractory prostate cancer patients who have progressed after response to prior docetaxel chemotherapy: RECARDO ST... not-yet-due
Ongoing 2007-004474-24 HD16 for early stages in Hodgkins Lymphoma not-yet-due
Ongoing 2007-004625-14 A phase II study of erlotinib and sorafenib in patients with locally advanced and/or metastatic (stage IIIB or IV) Non-Small cell lung cancer (NSCLC) who have not received prior chemotherapy not-yet-due
Ongoing 2007-005164-27 Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/ Interstitial Cystitis not-yet-due
Listed as ongoing, but also has a completion date 2007-005306-49 A phase II study of Vorinostat in patients with Polycythaemia Vera and Essential Thrombocythaemia 2012-08-15 bad-data
Ongoing 2007-005920-34 HD17 for Intermediate Stage Hodgkin Lymphoma - Treatment Optimization Trial in the First-Line Treatment of intermediate Stage Hodgkin lymhoma; Therapy stratification by means of FDG-PET not-yet-due
Ongoing 2007-007075-16 The effect of peroxisome proliferator activator receptor γ agonist pre-treatment on pegylated interferon-α2a and ribavirin efficacy in hepatitis C patients, previously resistant to treatment with pegy... not-yet-due
Ongoing 2008-005015-17 Effect of N-acetylcysteine on thiopurine related hepatotoxicity in IBD patients not-yet-due
Ongoing 2008-005325-10 The effect of exenatide compared to insulin glargine on cardiac function and metabolism in type 2 diabetic patients with congestive heart failure (NYHA II): a randomized-controlled trial not-yet-due
Not reported 2009-010758-36 Pyridostigmine: using a cholinesterase inhibitor to activate the cholinergic anti-inflammatory pathway in patients with CRPS-1 2011-04-28 due-trials
Ongoing 2009-011753-41 Pain treatment of newborns: paracetamol rectal versus intraveneous administration, an open randomised clinical trial. not-yet-due
Ongoing 2009-012944-17 Effect of a single dose of 14.8 MBq/kg (0.4 mCi/kg) 90Y-ibritumomab tiuxetan (“Zevalin”) following first-line R-CVP therapy in patients with follicular lymphoma on conversion rate assessed by FDG-PET ... not-yet-due
Ongoing 2009-013403-55 Early recognition and optimal treatment of delirium in patients with advanced cancer. not-yet-due
Ongoing 2009-014272-21 Effect of additional treatment with exenatide in patients with an acute myocardial infarction: the EXAMI trial) not-yet-due
Ongoing 2009-016080-11 A COMPREHENSIVE AND TARGETED THERAPY APPROACH IN PEDIATRIC MALIGNANT PONTINE GLIOMAS not-yet-due
Completed, but no date 2010-018327-26 Chemoradiation with gemcitabine in combination with panitumumab for patients with locally advanced pancreatic cancer. bad-data
Ongoing 2010-019252-41 DALI dosing study of Vitamin D in obese pregnant women not-yet-due
Ongoing 2010-019891-54 Effects of oral corticosteroids and DMSO on inflammatory signs and symptoms in Complex Regional Pain Syndrome type 1 not-yet-due
Ongoing 2010-019982-27 Targeted therapy selection based on tumor tissue kinase activity profiles for patients with advanced solid malignancies, an exploratory study not-yet-due
Ongoing 2010-020397-42 The efficacy of an antigenic marker lesion for the therapeutic effect in patients with multiple, Ta/T1, G1/G2, non-muscle invasive bladder cancer (NMIBC) treated with TUR followed by IL-2 instillation not-yet-due
Ongoing 2010-020424-21 Betablocker Therapy in Pulmonary Arterial Hypertension not-yet-due
Completed, but no date 2010-021797-10 A phase II randomized multicenter study on efficacy and safety of cultured autologous skin (Tiscover®) and acellular dermal matrix (AS210) in chronic (arterio-)venous ulcers bad-data
Completed, but no date 2010-021943-41 Treatment optimization of cetuximab in patients with metastatic colorectal cancer based on tumour uptake of 89Zr-labeled cetuximab assessed by PET bad-data
Ongoing 2010-023233-30 ‘Intravenous iron treatment in iron deficient patients with pulmonary arterial hypertension' not-yet-due
Ongoing 2010-023577-20 Revlimid, Endoxan, Prednisone Evaluation After prior revlimid Treatment (REPEAT): not-yet-due
Completed, but no date 2010-024515-13 Phase 1-2 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer. bad-data
Listed as ongoing, but also has a completion date 2011-000440-22 Multicenter prospective trial estimating the persistence of molecular remission in chronic myeloid leukemia after stopping TKI 2017-11-20 bad-data
Ongoing 2011-000538-12 An exploratory open-label PET-observer-blinded pilot study to evaluate the effect of 3 and 12 months treatment with Aliskeren-based versus amlodipin-based antihypertensive treatment in patients with a... not-yet-due
Ongoing 2011-000753-24 Central effects of endogenous GLP-1 and the GLP-1 analog liraglutide on brain satiety and reward circuits and feeding behavior in diabetes. not-yet-due
Ongoing 2011-001251-37 Exploring alternative wound care treatment for percutanous gastrostomy site infection: a prospective, randomized, open, blinded end-point (PROBE) design. not-yet-due
Completed, but no date 2011-002211-28 Perioperative selective decontamination of the digestive tract (SDD) in elective colorectal cancer patients: a multicenter randomized clinical trial bad-data
Ongoing 2011-003325-10 A randomized controlled trail on the effects of periconceptional and prenatal folic acid supplementation on congenital anomalies and preterm birth not-yet-due
Ongoing 2011-003570-89 The effect of interferon beta-1a treatment on functional adaptation in Multiple Sclerosis (MS) not-yet-due
Ongoing 2011-004446-17 Metoclopramide, dexamethasone or Aloxi for the prevention of delayed chemotherapy-induced nausea and vomiting in moderately emetogenic non-AC-based chemotherapy: the MEDEA trial not-yet-due
Completed, but no date 2011-004495-12 Antibiotic treatment alone for children with acute appendicitis; a prospective cohort study part of the Antibiotic versus Primary Appendectomy for Children with acute appendicitis; the APAC trial. bad-data
Ongoing 2011-004683-30 A phase II study of sorafenib and metformin in patients with locally advanced and/or metastatic non-smal cell lung cancer (NSCLC) with a K-Ras mutation not-yet-due
Completed, but no date 2011-004762-15 Early pharmacological intervention to prevent delirium: HAlopeRidol PrOphylaxis in Older emergency department patieNts. The HARPOON study bad-data
Ongoing 2011-005003-32 A randomized multicenter clinical trial for patients with multi-organ, colorectal cancer metastases comparing the combination of chemotherapy and maximal tumor debulking versus chemotherapy alone. not-yet-due
Ongoing 2011-005160-23 Hismys study. Misoprostol for cervical priming prior to hysteroscopy in postmenopausal and nulliparous premenopausal women; a multi-centre randomised placebo controlled trial not-yet-due
Ongoing 2011-005165-21 De-ESCALaTE HPV: Determination of Epidermal growth factor receptor-inhibitor (cetuximab) versus Standard Chemotherapy (cisplatin) early And Late Toxicity Events in Human Papillomavirus-positive oropha... not-yet-due
Ongoing 2011-006009-85 Prediction of response to kinase inhibitors based on protein phosphorylation profiles in tumor tissue from advanced renal cell cancer patients not-yet-due
Ongoing 2012-000345-12 A phase II study of gefitinib and fulvestrant in patients with advanced, EGFR mutated non-small cell lung cancer pretreated with reversible EGFR tyrosine kinase inhibitors not-yet-due
Ongoing 2012-000850-75 Clinical evaluation of the efficacy of methylnaltrexone in resolving constipation induced by different opioid subtypes combined with laboratory analysis of immunomodulatory and antiangiogenic effects ... not-yet-due
Completed, but no date 2012-001530-34 Varenicline, a partial nicotinic receptor agonist for the treatment of Excessive Daytime Sleepiness in Parkinson’s Disease: a placebo-controlled cross-over study bad-data
Ongoing 2012-001541-40 Effect of Carbon Dioxide Enriched Ambient Air on Pharmacokinetics and Deposition In Bronchiectasis Patients Using Tobramycin Inhalation: A proof of concept study. not-yet-due
Ongoing 2012-001597-29 Tumor uptake of 89Zirconium-ofatumumab and 89Zirconium-rituximab in diffuse large B cell lymphoma patients not-yet-due
Ongoing 2012-001599-12 The clinical value of amyloid imaging with [18F]-AV45 in a population of memory clinic patients not-yet-due
Completed, but no date 2012-002303-18 The Dutch Flutemetamol in Young Dementia Study bad-data
Ongoing 2012-003141-16 Efficacy and feasibility of first-line treatment with risk-adapted not-yet-due
Ongoing 2012-003256-36 A phase IV, randomized, double-blind, placebo-controlled, parallel-group trial to assess the effect of 12-week treatment with the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide or dipe... not-yet-due
Ongoing 2012-003359-12 The effect of a high and low protamine-to-heparin dosing on perioperative hemostasis: a randomized clinical trial. not-yet-due
Ongoing 2012-003616-31 Uptake and biodistribution of 89Zirconium-labeled ipilimumab in ipilimumab treated patients with metastatic melanoma not-yet-due
Completed, but no date 2012-003981-42 Estrogen receptor and androgen receptor imaging in metastatic breast cancer patients bad-data
Ongoing 2012-004321-25 A phase II, single arm, multicenter study of nilotinib in combination with pegylated interferon α2b in patients with suboptimal molecular response or stable detectable molecular residual disease after... not-yet-due
Ongoing 2012-004961-42 Measurement of tumor kinase inhibitor concentrations using PET imaging in patients with advanced solid malignancies not-yet-due
Ongoing 2012-005066-36 Effect of Growth Hormone replacement therapy on cardiovascular risk factors in adult patients with severe growth hormone deficiency: association with IGF-I concentration not-yet-due
Completed, but no date 2012-005332-29 Prevention of depression and poor physical function in older persons with vitamin D supplementation bad-data
Ongoing 2013-000238-37 Treatment guided by detection of Minimal Residual Disease after allogeneic stem cell transplantation in Acute Myeloid Leukaemia not-yet-due
Ongoing, reported early 2013-000789-13 DALI: Vitamin D And Lifestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention - A European multicentre, randomised trial not-yet-due
Ongoing 2013-001722-25 Cholinesterase inhibitors to slow progression of visual hallucinations in Parkinson’s disease: a multi-center placebo-controlled trial (CHEVAL) not-yet-due
Ongoing 2013-001743-31 The cardiovascular effects of hyperoxia during and shortly after CABG surgery not-yet-due
Ongoing 2013-002023-41 Image guided treatment optimalization with cetuximab for patients with metastatic colorectal cancer: IMPACT - CRC not-yet-due
Ongoing 2013-002563-25 Pilot study to determine the effect of fractionated radiotherapy on expression of pro-angiogenic factors in oeshophagus carcinoma not-yet-due
Ongoing 2013-002663-25 A phase I- IIa open-label clinical trial, evaluating the therapeutic vaccine hVEGF26-104/RFASE in patients with advanced solid tumors not-yet-due
Ongoing 2013-002670-40 Noninvasive Imaging of Vulnerable Inflammatory Coronary Plaque using Cardiac PET/CT in Humans: a feasibility study not-yet-due
Ongoing 2013-003354-24 Influence of exogenous growth hormone administration on circulating levels of Klotho in healthy and CKD subjects not-yet-due
Ongoing 2013-003658-26 Treat-to-target strategy for early RA patients in usual clinical practice: The COBRA Cohort Study not-yet-due
Ongoing 2013-003733-15 The Dutch CSF and PET Biomarker Concordance of Alzheimer’s Disease pathology study not-yet-due
Ongoing 2013-003949-41 Role of different phosphate binders on absorption of vitamin K, metabolism of matrix γ-carboxy-glutamaat (Gla) proteïne (MGP). not-yet-due
Ongoing 2013-004120-11 PI3K pathway analysis in tumor tissue and circulating DNA to obtain further insight in the efficacy of everolimus when combined with exemestane. not-yet-due
Ongoing 2013-004635-69 A phase II study of obinutuzumab monotherapy not-yet-due
Ongoing 2014-000047-33 The effect of high-resistance muscle strength training and vitamin D not-yet-due
Ongoing 2014-000219-15 Amyloid pathology in cognitively normal elderly subjects not-yet-due
Ongoing 2014-000304-96 Sentinel lymph node identification in colon cancer using a radioactive and fluorescent tracer not-yet-due
Ongoing 2014-000562-21 Amyloid-PET as a diagnostic marker in daily practice. not-yet-due
Ongoing 2014-001012-19 Effects of fingolimod on functional brain adaptation and clinical measures in multiple sclerosis not-yet-due
Ongoing 2014-001546-25 Short versus extended antibiotic treatment with a carbapenem for high-risk febrile neutropenia in hematology patients with Fever of Unknown Origin: a randomized multicenter open-label non-inferiority ... not-yet-due
Ongoing 2014-001561-27 Vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia: comparing one-hour infusions with bolus injections (the VINCA-study) not-yet-due
Ongoing 2014-002178-35 A phase 4, monocenter, randomized, open label, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 8-week treatment with the glucagon-like peptide-1 receptor ... not-yet-due
Ongoing 2014-002514-23 Reduction Of Microvascular Injury Utilizing Sonolysis not-yet-due
Not reported 2014-002547-17 Grey matter microglial imaging with [18F]DPA-714 in progressive MS patients 2016-01-21 due-trials
Completed, but no date 2014-002832-15 Ulipristal versus Gonadotropin-releasing hormone agonists prior to laparoscopic myomectomy: a double blind randomized controlled trial bad-data
Ongoing 2014-002928-27 Observing Platelet Activability in a Once daily vs. a More frequent Aspirin intake regimen not-yet-due
Ongoing 2014-003385-24 The Recall-study: Rivastigmine for ECT-induced Cognitive Adverse effects in Late Life Depression: a multicenter, randomized, double-blind, placebo-controlled, crossover trial not-yet-due
Ongoing 2014-003468-19 The effects of hyperoxia on organ dysfunction and outcome in critically ill patients with SIRS not-yet-due
Ongoing 2014-003469-10 The application of contrast-enhanced ultrasound to facilitate thrombolysis in patients with acute peripheral arterial occlusions. not-yet-due
Ongoing 2014-003680-38 Pharmacokinetics of two different high dose regimes of intravenous vitamin C in critically ill patients not-yet-due
Completed, but no date 2014-003932-38 Advanced imaging in laparoscopic HIPEC for peritoneal carcinomatosis of colorectal orgin to improve cytoreduction; a feasibility study bad-data
Ongoing 2014-004739-38 Follow-up of the FRUIT-RCT; aspirin resistance and cardiovascular risk factors in women after recurrent hypertensive disorders in pregnancy not-yet-due
Ongoing 2014-005363-33 Reducing Micro Vascular dysfunction In revascularized STEMI patients by off-target properties of ticagrelor not-yet-due
Ongoing 2015-000644-42 Laparoscopic advanced Imaging Techniques in Endometriosis therapy: LITE-study. A pilot trial. not-yet-due
Ongoing 2015-002729-21 The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study Comparing the cost-effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rh... not-yet-due
Ongoing 2015-003220-31 Low dose aspirin in the Prevention of Recurrent Spontaneous Preterm Labour – the APRIL study not-yet-due
Completed, but no date 2015-003554-41 A phase I/II “minor histocompatibility antigen UTA2-1 loaded, PD-L silenced Dendritic cell vaccination trial after allogeneic Stem Cell Transplantation to improve the safety and efficacy of Donor Lym... bad-data
Ongoing 2015-003705-42 Longitudinal imaging of tau accumulation in the preclinical stages of AD not-yet-due
Ongoing 2015-003818-24 A phase 4, monocenter, randomized, double-blind, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 12-week treatment with the sodium-glucose linked transpor... not-yet-due
Ongoing 2015-003862-10 A phase 1 and phase 2 study of daratumumab in combination with all-trans retinoic acid in relapsed/refractory multiple myeloma not-yet-due
Ongoing 2015-004230-10 Validating in vivo quantification of tau with [18F]AV-1451 PET not-yet-due
Ongoing 2015-004260-10 89Zirconium-labeled pembrolizumab as predictive imaging biomarker of response and toxicity in pembrolizumab treated patients with non-small-cell lung cancer – a feasibility study not-yet-due
Ongoing 2015-004760-11 89Zirconium-labeled nivolumab and 18F-labeled anti-PD-L1 as predictive imaging biomarkers of response and toxicity in nivolumab treated patients with non-small-cell lung cancer – a feasibility study not-yet-due
Ongoing 2015-004937-29 Towards early identification of response to CABAZItaxel in patients with metastatic castration-resistant prostate cancer: potential of 18F-Choline PET-CT (CABAZIPET). not-yet-due
Ongoing 2015-004998-33 Multicenter prospective trial after first unsuccesful treatment discontinuation in chronic myeloid leukemia estimating the efficacy of nilotinib in inducing the persistance of molecular remission afte... not-yet-due
Ongoing 2015-005604-29 Tau-imaging in tauopathies; Alzheimer’s disease and non-AD dementias not-yet-due
Ongoing 2015-005765-23 Companion biomarker development for MEDI4736 treated non-small-cell lung cancer patients using 89Zirconium-labeled MEDI4736 – a feasibility study not-yet-due
Ongoing 2015-005811-34 Pregnancy reLated Acute hyperTension INtervention Action: a randomized trial comparing labetalol and nicardipine in women with acute hypertension in pregnancy (Platina-trial) not-yet-due
Ongoing 2016-000345-31 Towards personalized dosing of natalizumab in multiple sclerosis not-yet-due
Ongoing 2016-001353-41 Oxygenation of Affected Limbs in CRPS-I Patients not-yet-due
Ongoing 2016-001797-15 A phase II/III study of high-dose, intermittent sunitinib in patients with recurrent glioblastoma multiforme not-yet-due
Completed, but no date 2016-002342-23 The cardiovascular dose-response to supplemental oxygen in healthy volunteers bad-data
Ongoing 2016-002635-15 Study to Identify Factors associated with Resilience to Clinical Dementia at Old Age not-yet-due
Ongoing 2016-003819-36 Combining SBRT and pembrolizumab in early stage non-small cellular lungcancer patients planned for surgery: exploring safety and immunological proof of principle. not-yet-due
Ongoing 2016-004303-32 ASsesment of Platelet function and Inhibition in patients Recovering from severe INfection not-yet-due
Ongoing 2016-004545-91 Continuous use of Oral contraceptives as an alternative for long term Pituitary down-regulation with a GnRH agonist prior to IVF/ICSI in Endometriosis patients: a randomised controlled trial not-yet-due
Ongoing 2017-000137-31 Pulmonary Hypertension REversal in Clusters of Patients With Identical Pathobiological Substrates. 6-Mercaptopurine Proof-of-Concept Trial not-yet-due
Ongoing 2017-000169-60 A phase 2 study of nivolumab combined with daratumumab with or without lenalidomide-dexamethasone in relapsed/refractory multiple myeloma not-yet-due
Ongoing 2017-000699-27 Repeated Rhenium-188-HEDP versus Radium-223-chloride in patients with metastatic castration-resistant prostate cancer; the RARE trial not-yet-due
Ongoing 2017-000841-28 Combined effects of SGLT2 inhibition and GLP-1 receptor agonism on food intake, body weight and central satiety and reward circuits in obese T2DM patients not-yet-due
Ongoing 2017-001547-12 A phase 4, monocenter, randomized, double-blind, comparator-controlled, 3-armed parallel mechanistic intervention trial to assess the effect of 8-week empagliflozin (SGLT-2 inhibitor) monotherapy, fol... not-yet-due
Ongoing 2017-002022-20 The effect of inspiratory oxygen fraction on the ratio of partial arterial oxygen pressure and inspiratory oxygen fraction (PaO2/FiO2 ratio) in mechanically ventilated patients with and without mild t... not-yet-due
Ongoing 2017-002478-37 Right Dose, Right Now: Randomized Clinical Trial not-yet-due
Ongoing 2017-002636-16 Cognitive impairment and functional reorganization in multiple sclerosis: The role of GABA and glutamate not-yet-due
Ongoing 2017-003072-31 The effects of sex hormone administration on marrow and visceral adiposity not-yet-due
Ongoing 2017-003860-11 11C-erlotinib brain uptake in Diffuse Intrinsic Pontine Glioma imaged by PET not-yet-due
Ongoing 2017-004850-40 [18F]Fluoride PET-CT imaging for detection and monitoring of bone formation in spondyloarthritis not-yet-due