These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Ongoing 2004-001876-37 BENEFIT-study: A randomized placebo controlled trial of anti-TNF-alpha chimeric monoclonal antibody ( infliximab) in idiopathic pulmonary fibrosis. not-yet-due
Not reported Terminated 2004-002783-24 Prednisolone versus Dexamethasone in Chronic inflammatory demyelinating polyradiculoneuropathy Trial; PREDICT-trial 2008-12-01 due-trials
Listed as ongoing, but also has a completion date 2005-000217-35 EpSSG RMS 2005 a protocol for non metastatic rhabdomyosarcoma 2016-12-31 bad-data
Ongoing 2005-001062-14 MACS Macrolides in chronic rhinosinusitis Double-blind, randomized, placebo-controlled, multinational, multicenter-trial on prolonged macrolide treatment in patients with moderate/ severe chronic rh... not-yet-due
Ongoing 2005-005745-18 Levamisole treatment for children with steroid sensitive nephrotic syndrome. A multi-centre, double-blind, placebo-controlled, randomised trial. not-yet-due
Ongoing 2006-002081-19 The Effects of EGFR Inhibition on Pulmonary Arterial Hypertension Associated with Systemic Sclerosis A phase II open-label safety and efficacy study. not-yet-due
Ongoing 2006-002392-40 First international trial for diagnosia nd treatment of langerhans cell histiocytosis in adults not-yet-due
Ongoing 2006-003003-39 Methotrexate versus expectant management in women with ectopic pregnancy (METEX study) not-yet-due
Exempt 2006-003149-17 Phase I study of concurrent with involved-field thoracic radiotherapy for inoperable non-squamous cell lung cancer, followed by both concurrent and maintenance Bevacizumab not-yet-due
Ongoing 2006-003418-16 The role of a hiatal hernia on the efficacy of anti-TLESR therapy in patients with gastroesophageal reflux disease not-yet-due
Not reported 2006-003483-59 PRESERVE TRIAL: Pancreatic beta-cell dysfunction REStorEd by Rosiglitazone and Valsartan Effects; A 52-week randomized controlled factorial study in subjects with impaired fasting glucose and/or impai... 2009-11-03 due-trials
Ongoing 2006-004199-11 NOSTRADAMUS: Testing for thrombophilia in patients with a first episode of venous thromboembolism: a randomized controlled trial to assess effects on clinical outcomes, quality of life, and costs. not-yet-due
Ongoing 2006-005602-31 Excimer laser versus clobetason propionaat in prurigo form of atopic dermatitis not-yet-due
Ongoing 2006-005889-40 N-Acetylcysteine for Treatment of Sickle Cell Disease not-yet-due
Ongoing 2006-006058-83 Phase II randomized trial of combination therapy of paclitaxel and bevacizumab versus paclitaxel, capecitabine and bevacizumab as first-line treatment for locally recurrent or metastatic breast cancer... not-yet-due
Ongoing 2006-006203-36 Dopaminergic neurotransmission and cognitive decline in velocardiofacial syndrome not-yet-due
Ongoing 2007-000488-38 Bevacizumab in combination with metronomic dose temozolomide in patients with relapsed high grade gliomas not-yet-due
Exempt 2007-002962-37 Phase I/II study of dalteparin, a low molecular weight heparin (LMWH), in combination with Sunitinib (SU11248), an oral, selective multitargeted tyrosine kinase inhibitor, as first line treatment, in ... 2015-10-14 not-yet-due
Reported results 2007-003187-22 Clinical trials for adults HD18 for advanced stages Treatment optimization trial in the first-line treatment of advanced stage Hodgkin lymphoma; treatment stratification by means of FDG-PET Therapi... 2019-07-18 due-trials
Ongoing 2007-003343-74 A methodological investigation to test acute changes in female sexual desire in healthy volunteersand pre- and postmenopausal women diagnosed with hypoactive sexual desiredisordersusing explicit measu... not-yet-due
Ongoing 2007-004335-39 A randomized phase II trial of docetaxel plus carboplatin versus docetaxel in hormone refractory prostate cancer patients who have progressed after response to prior docetaxel chemotherapy: RECARDO ST... not-yet-due
Reported results 2007-004474-24 HD 16 for early stages: treatment optimization trial in the first-line treatment of early stage Hodgkin lymphoma; treatment stratification by means of FDG-PET. 2020-12-29 due-trials
Ongoing 2007-004625-14 A phase II study of erlotinib and sorafenib in patients with locally advanced and/or metastatic (stage IIIB or IV) Non-Small cell lung cancer (NSCLC) who have not received prior chemotherapy not-yet-due
Exempt 2007-005164-27 Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/ Interstitial Cystitis not-yet-due
Not reported 2007-005306-49 A Phase II Study Of Vorinostat (MK-0683) In Patients With Polycythaemia Vera And Essential Thrombocythaemia 2012-08-15 due-trials
Ongoing 2007-005644-24 Bevacizumab, Radiotherapy and Temozolomide Safety study in resected and irresectable primary GBM patients not-yet-due
Reported results 2007-005920-34 HD17 for Intermediate Stage Hodgkin Lymphoma - Treatment Optimization Trial in the First-Line Treatment of intermediate Stage Hodgkin lymhoma; Therapy stratification by means of FDG-PET 2020-03-21 due-trials
Ongoing 2007-006233-14 Organ protection by noble gases – Helium induced Early and Late Preconditioning (HELP) in human endothelium not-yet-due
Ongoing 2007-006277-92 Treatment of anal intraepithelial neoplasia in HIV-positive patients, a triple-arm randomized clinical trial not-yet-due
Ongoing 2007-007075-16 The effect of peroxisome proliferator activator receptor γ agonist pre-treatment on pegylated interferon-α2a and ribavirin efficacy in hepatitis C patients, previously resistant to treatment with pegy... not-yet-due
Ongoing 2007-007974-45 Phase II trial of the addition of gemcitabine to 131I-MIBG therapy in paediatric patients with relapsed or progressive neuroblastoma not-yet-due
Ongoing 2008-000992-12 Organ protection by noble gases – A clinical study to investigate Helium induced Pre- and Postconditioning in patients undergoing coronary artery bypass surgery (HIPP-CABG). not-yet-due
Ongoing 2008-000996-57 The effects of melatonin the occurence of on post-operative delirium in hip fracture patients – a randomized double-blind placebo controlled trial not-yet-due
Ongoing 2008-001131-35 Azathioprine maintenance treatment versus Infliximab maintenance treatment in Crohn's disease patients in remission: a randomized multicenter trial not-yet-due
Ongoing 2008-001308-22 Aspirin sensitivity in diabetes mellitus; the role of glycaemic control and dosing not-yet-due
Ongoing 2008-001786-28 Innovative approaches for cocaine pharmacotherapy using fMRI: The case of varenicline not-yet-due
Ongoing 2008-002236-15 A phase II study in patients with fludarabine refractory CLL: Dasatinib treatment combination for Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL) not-yet-due
Ongoing 2008-002610-21 Mechanisms of albuminuria in diabetes; reversal of injury to the glycocalyx by the ACE inhibitor lisinopril not-yet-due
Ongoing 2008-003623-23 Effect of different antipsychotic medication on craving related brain activity in patients with schizophrenia and cannabis abuse or dependence: a randomized controlled study comparing clozapine and ri... not-yet-due
Ongoing 2008-005015-17 Effect of N-acetylcysteine on thiopurine related hepatotoxicity in IBD patients not-yet-due
Ongoing 2008-005019-16 Randomized Olanzapine Clozapine Key study on Schizophrenia and Addiction in the Netherlands (ROCKSAN) not-yet-due
Ongoing 2008-005325-10 The effect of exenatide compared to insulin glargine on cardiac function and metabolism in type 2 diabetic patients with congestive heart failure (NYHA II): a randomized-controlled trial not-yet-due
Completed, but no date 2008-005438-57 Predictive value of drug elimination gene polymorphisms on clearance and dose adjustment of sunitinib (Sutent, SU11248) in patients with cancer bad-data
Reported results 2008-005598-36 Optimal timing of rapid-acting insulin analogues administration before meal 2010-02-26 due-trials
Ongoing 2008-005987-15 Preventing preterm birth: Costs and effects of screening of healthy women with a singleton pregnancy for a short cervical length. not-yet-due
Ongoing 2008-006452-22 The effects of melatonin in the treatment of delirium not-yet-due
Ongoing 2008-006903-22 Narrow band UV-B phototherapy and fluticasone proprionate versus narrow band UV-B phototherapy and placebo for the treatment of active vitiligo: a randomized double blind controlled trial not-yet-due
Completed, but no date Terminated 2008-007020-25 Glucose lowering by continuous tube feeding and Vildagliptin in addition to insulin in hyperglycemic acute stroke patients. bad-data
Exempt 2008-007344-34 External Cephalic Version with uterine relaxation: atosiban versus fenoterol, a multi-centre trial not-yet-due
Ongoing 2008-007492-24 An independent prospective randomised controlled trial comparing the efficacy and cost effectiveness of infliximab and etanercept in 'high need' patients with moderate to severe chronic plaque type ps... not-yet-due
Completed, but no date 2008-008209-22 Chemoradiation combined with panitumumab followed by surgery for patients with operable esophageal cancer bad-data
Ongoing 2009-010078-39 The effect of helium on the immune system ex vivo not-yet-due
Not reported 2009-010758-36 Pyridostigmine: using a cholinesterase inhibitor to activate the cholinergic anti-inflammatory pathway in patients with CRPS-1 2011-04-28 due-trials
Ongoing 2009-010955-29 Prevention of clinically manifest rheumatoid arthritis by B cell directed therapy in the earliest phase of the disease. not-yet-due
Ongoing 2009-011132-34 A 24 week multinational multi-center study consisting of a 12-week single blind study to evaluate the efficacy and safety of methotrexate versus Azathioprin treatment in adult patients with chronic se... not-yet-due
Reported results 2009-011208-42 First trimester progesterone therapy in women with a history of unexplained recurrent miscarriages: A randomised, double-blind, placebo-controlled, multi-centre trial [The PROMISE (PROgesterone in rec... 2015-10-31 due-trials
Ongoing 2009-011753-41 Pain treatment of newborns: paracetamol rectal versus intraveneous administration, an open randomised clinical trial. not-yet-due
Completed, but no date, and reported results Terminated 2009-011824-79 Effects of fluoxetine on the outgrowth of the serotonergic system bad-data
Ongoing 2009-012261-61 Why methylphenidate is not successful in cocaine-dependent ADHD patients: a SPECT study comparing DAT before and after methylphenidate treatment in ADHD patients with and without cocaine dependence not-yet-due
Ongoing 2009-012944-17 Effect of a single dose of 14.8 MBq/kg (0.4 mCi/kg) 90Y-ibritumomab tiuxetan (“Zevalin”) following first-line R-CVP therapy in patients with follicular lymphoma on conversion rate assessed by FDG-PET ... not-yet-due
Ongoing 2009-013080-19 Prokinetics to alter the position of the gastric acid pocket in Gastro Esophageal Reflux Disease not-yet-due
Ongoing 2009-013403-55 Early recognition and optimal treatment of delirium in patients with advanced cancer. not-yet-due
Ongoing 2009-014272-21 Effect of additional treatment with exenatide in patients with an acute myocardial infarction: the EXAMI trial) not-yet-due
Ongoing 2009-015336-15 Long-term treatment for cancer patients with deep vein thrombosis or pulmonary embolism - a randomized open label study not-yet-due
Ongoing 2009-015782-30 Nifedipine versus Atosiban in the treatment of threatened preterm labour not-yet-due
Ongoing 2009-016751-22 A double blind, placebo controlled study of memantine in patients with obsessive-compulsive disorder. not-yet-due
Ongoing 2009-016789-10 Efficacy of the H1N1 Flu (swine flu) vaccination in patients with Rheumatoid Arthritis treated with rituximab not-yet-due
Ongoing 2009-017014-80 The effect of helium inhalation on the coronary circulation and vessel diameter not-yet-due
Ongoing 2009-017060-17 STIMULATE study: Statins influence on Minrin upregulation of von Willebrand factor and factor VIII not-yet-due
Ongoing 2009-017499-26 The use of Helium after Resuscitation: a safety and feasibility study not-yet-due
Ongoing 2009-017716-32 A phase II, randomized, placebo controlled study to evaluate the efficacy of the combination of gemcitabine, erlotinib and metformin in patients with locally advanced and metastastatic pancreatic canc... not-yet-due
Completed, but no date 2009-018016-25 Dopamine-serotonin dysbalance in patients with dystonia bad-data
Exempt Terminated 2010-018327-26 Chemoradiation with gemcitabine in combination with panitumumab for patients with locally advanced pancreatic cancer. not-yet-due
Completed, but no date 2010-018421-19 Preventive Antibiotics in Stroke Study bad-data
Ongoing 2010-019252-41 DALI dosing study of Vitamin D in obese pregnant women not-yet-due
Ongoing 2010-019891-54 Effects of oral corticosteroids and DMSO on inflammatory signs and symptoms in Complex Regional Pain Syndrome type 1 not-yet-due
Ongoing 2010-019982-27 Targeted therapy selection based on tumor tissue kinase activity profiles for patients with advanced solid malignancies, an exploratory study not-yet-due
Ongoing 2010-020397-42 The efficacy of an antigenic marker lesion for the therapeutic effect in patients with multiple, Ta/T1, G1/G2, non-muscle invasive bladder cancer (NMIBC) treated with TUR followed by IL-2 instillation not-yet-due
Ongoing 2010-020424-21 Betablocker Therapy in Pulmonary Arterial Hypertension not-yet-due
Ongoing 2010-020451-32 Pilot study of everolimus in the treatment of advanced malignancies in patients with Peutz-Jeghers syndrome not-yet-due
Ongoing 2010-021150-19 Doxycycline versus minocycline in the treatment of rosacea: a randomised controlled trial. not-yet-due
Ongoing 2010-021435-14 Effects of abatacept (Orencia®) on biomarkers in synovial tissue in patients with rheumatoid arthritis not-yet-due
Completed, but no date Terminated 2010-021797-10 A phase II randomized multicenter study on efficacy and safety of cultured autologous skin (Tiscover®) and acellular dermal matrix (AS210) in chronic (arterio-)venous ulcers bad-data
Completed, but no date 2010-021943-41 Treatment optimization of cetuximab in patients with metastatic colorectal cancer based on tumour uptake of 89Zr-labeled cetuximab assessed by PET bad-data
No trial status on register 2010-022046-25 Cholic acid treatment in Peroxisomal Biogenesis Disorders (Zellweger spectrum): biochemical and clinical effects. bad-data
Ongoing 2010-022393-13 Does helium protect the heart against ischaemia-reperfusion damage in patients with acute myocardial infarction? not-yet-due
Completed, but no date 2010-023185-42 Proof-of-concept double-blind, placebo-controlled, randomized clinical trial with nilotinib in spondyloarthritis bad-data
Ongoing 2010-023233-30 ‘Intravenous iron treatment in iron deficient patients with pulmonary arterial hypertension' not-yet-due
Exempt 2010-023577-20 Revlimid, Endoxan, Prednisone Evaluation After prior revlimid Treatment (REPEAT): A phase 1 and phase 2 study of lenalidomide (Revlimid) in combination with cyclophosphamide (endoxan) and prednisone (... not-yet-due
Reported results 2010-023654-37 Effects of methylphenidate on the development of the dopaminergic system in the brain 2015-06-17 due-trials
Other 2010-023777-19 Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants: the SToP-BPD study not-yet-due
Exempt Terminated 2010-024515-13 Phase 1-2 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer. not-yet-due
Completed, but no date, and reported results 2011-000026-30 Induction of Labour with a Foley catheter or oral Misoprostol at Term bad-data
Ongoing 2011-000129-61 ASB treat study: Preventing preterm birth with nitrofurantoin: Costs and effects of screening and treating healthy women for asymptomatic bacteriuria’ not-yet-due
Completed, but no date, and reported results Terminated 2011-000174-66 Assessment of Perinatal Outcome by uSe of Tocolysis in Early Labour (APOSTEL IV); Nifedipine versus placebo in the treatment of preterm premature rupture of membranes bad-data
Ongoing 2011-000538-12 An exploratory open-label PET-observer-blinded pilot study to evaluate the effect of 3 and 12 months treatment with Aliskeren-based versus amlodipin-based antihypertensive treatment in patients with a... not-yet-due
Ongoing 2011-000586-12 The efficacy of mepolizumab treatment on rhinovirus induced asthma exacerbations not-yet-due
Ongoing 2011-000753-24 Central effects of endogenous GLP-1 and the GLP-1 analog liraglutide on brain satiety and reward circuits and feeding behavior in diabetes. not-yet-due
Ongoing 2011-001251-37 Exploring alternative wound care treatment for percutanous gastrostomy site infection: a prospective, randomized, open, blinded end-point (PROBE) design. not-yet-due
Not reported Terminated 2011-001820-39 Levothyroxine for euthyroid women with recurrent miscarriage and thyroid autoimmunity : a randomized controlled trial 2021-07-30 due-trials
Not reported 2011-002211-28 Perioperative selective decontamination of the digestive tract (SDD) in elective colorectal cancer patients: a multicenter randomized clinical trial 2020-03-25 due-trials
Ongoing 2011-003325-10 A randomized controlled trail on the effects of periconceptional and prenatal folic acid supplementation on congenital anomalies and preterm birth not-yet-due
Ongoing 2011-003570-89 The effect of interferon beta-1a treatment on functional adaptation in Multiple Sclerosis (MS) Het effect van interferon beta-1a behandeling op functionele adaptatie in Muliple Sclerose (MS not-yet-due
Completed, but no date, and reported results Terminated 2011-004177-83 Boosting the oxytocin system in acute trauma: The effectiveness of intranasal oxytocin treatments and stimulation of social support on preventing trauma related psychopathology Versterken van het ... bad-data
Reported results 2011-004206-19 Patient and Endoscopist Satisfaction with DEXmedetomidine versus Propofol/Alfentanil sedation during oesophagus interventions (PESDEX). Ondervindingen van patiënten en endoscopist met dexmedetomidi... 2013-04-26 due-trials
Ongoing 2011-004265-32 Left Ventricular Thrombus Formation after Acute Myocardial Infarction - a randomized multi-center trial comparing 2 different anti-thrombotic regimens Linker Ventrikel Thrombus Formatie na het Acu... not-yet-due
Completed, but no date Terminated 2011-004446-17 Metoclopramide, dexamethasone or Aloxi for the prevention of delayed chemotherapy-induced nausea and vomiting in moderately emetogenic non-AC-based chemotherapy: the MEDEA trial bad-data
Completed, but no date, and reported results 2011-004495-12 Antibiotic treatment alone for children with acute appendicitis; a prospective cohort study part of the Antibiotic versus Primary Appendectomy for Children with acute appendicitis; the APAC trial. bad-data
Ongoing 2011-004683-30 A phase II study of sorafenib and metformin in patients with locally advanced and/or metastatic non-smal cell lung cancer (NSCLC) with a K-Ras mutation not-yet-due
Completed, but no date 2011-004762-15 Early pharmacological intervention to prevent delirium: HAlopeRidol PrOphylaxis in Older emergency department patieNts. The HARPOON study Preventie van delirium door vroegtijdige pharmacologische i... bad-data
Ongoing 2011-004955-38 Controlling Glucose during Elective hip Surgery to study the influence on Coagulation not-yet-due
Ongoing 2011-005003-32 A randomized multicenter clinical trial for patients with multi-organ, colorectal cancer metastases comparing the combination of chemotherapy and maximal tumor debulking versus chemotherapy alone. not-yet-due
Ongoing 2011-005160-23 Hismys study. Misoprostol for cervical priming prior to hysteroscopy in postmenopausal and nulliparous premenopausal women; a multi-centre randomised placebo controlled trial not-yet-due
Ongoing 2011-005165-21 De-ESCALaTE HPV: Determination of Epidermal growth factor receptor-inhibitor (cetuximab) versus Standard Chemotherapy (cisplatin) early And Late Toxicity Events in Human Papillomavirus-positive oropha... not-yet-due
Ongoing 2011-006009-85 Prediction of response to kinase inhibitors based on protein phosphorylation profiles in tumor tissue from advanced renal cell cancer patients not-yet-due
Ongoing 2011-006165-18 A randomized double blind placebo controlled study on the effects of fenretinide Lym-X-Sorb on insulin sensitivity in obese insulin resistant subjects Een gerandomiseerde dubbelblinde placebogecont... not-yet-due
Reported results 2012-000343-26 Ultra-early tranexamic acid after subarachnoid hemorrhage. A prospective, randomized, multicenter study. Ultra-vroege toediening van tranexaminezuur na een subarachnoïdale bloeding. Een prospectiev... 2020-01-20 due-trials
Ongoing 2012-000345-12 A phase II study of gefitinib and fulvestrant in patients with advanced, EGFR mutated non-small cell lung cancer pretreated with reversible EGFR tyrosine kinase inhibitors Een Fase II studie van ge... not-yet-due
Ongoing 2012-000543-27 A Proof of Concept Study to Determine the Local Delivery and Efficacy of Intravenously Injected PEG-Liposomal Prednisolone Sodium Phosphate (Nanocort®) in Atherosclerotic Tissue in Subjects with Perip... not-yet-due
Completed, but no date, and reported results 2012-000680-24 Pain management after operative treatment of extremity fractures, a randomized clinical trial bad-data
Ongoing 2012-000850-75 Clinical evaluation of the efficacy of methylnaltrexone in resolving constipation induced by different opioid subtypes combined with laboratory analysis of immunomodulatory and antiangiogenic effects ... not-yet-due
Completed, but no date, and reported results 2012-001288-58 Boosting oxytocin after trauma: The effects of intranasal oxytocin administration on emotional and motivational brain processes in PTSD Versterken van oxytocine na trauma: De effecten van intrana... bad-data
Ongoing 2012-001447-43 Anticoagulants for Living Fetuses in women with recurrent miscarriage and inherited thrombophilia; ALIFE2 study not-yet-due
Listed as ongoing, but also has a completion date and reported results 2012-001505-24 Highlow study Low-molecular-weight heparin to prevent recurrent VTE in pregnancy: a randomized controlled trial of two doses 2021-10-31 bad-data
Completed, but no date Terminated 2012-001530-34 Varenicline, a partial nicotinic receptor agonist for the treatment of Excessive Daytime Sleepiness in Parkinson’s Disease: a placebo-controlled cross-over study bad-data
Ongoing 2012-001541-40 Effect of Carbon Dioxide Enriched Ambient Air on Pharmacokinetics and Deposition In Bronchiectasis Patients Using Tobramycin Inhalation: A proof of concept study. Het effect van koolstofdioxide ve... not-yet-due
Ongoing 2012-001597-29 Tumor uptake of 89Zirconium-ofatumumab and 89Zirconium-rituximab in diffuse large B cell lymphoma patients Tumor opname van 89Zirconium-ofatumumab en 89Zirconium-rituximab bij patienten met een dif... not-yet-due
Not reported Terminated 2012-001599-12 The clinical value of amyloid imaging with [18F]-AV45 in a population of memory clinic patients 2022-05-16 due-trials
Completed, but no date 2012-002303-18 The Dutch Flutemetamol in Young Dementia Study De Nederlandse Flutemetamol in Vroege Dementie Study bad-data
Not reported Terminated 2012-002891-15 Phase II study of sunitinib rechallenge in patients with metastatic renal cell carcinoma. 2017-04-20 due-trials
Ongoing 2012-003072-39 Oxytocin in PTSD: effectiveness as addition to Narrative Exposure Therapy Oxytocine bij PTSS: Effectiviteit als toevoeging bij Narratieve exposure therapie not-yet-due
Exempt, with results 2012-003097-45 Phase I/II feasibility study combining Brentuximab Vedotin (Adcetris) with second line salvage chemotherapy (DHAP) in Hodgkin lymphoma patients refractory to first line chemotherapy or in first relaps... 2020-10-23 not-yet-due
Ongoing 2012-003141-16 Efficacy and feasibility of first-line treatment with risk-adapted dose-adjusted EPOCH-R (DA-EPOCH-R) in patients with Burkitt lymphoma. A phase II clinical trial. not-yet-due
Completed, but no date Terminated 2012-003289-42 Randomized Controlled Trial Investigating the Efficacy and Safety of Nebulized Heparin versus Placebo in Burn Patients with Inhalation Trauma bad-data
Ongoing 2012-003359-12 The effect of a high and low protamine-to-heparin dosing on perioperative hemostasis: a randomized clinical trial. Het effect van een hoge en lage protamine:heparine doseringsratio op perioperatie... not-yet-due
Ongoing 2012-003616-31 Uptake and biodistribution of 89Zirconium-labeled ipilimumab in ipilimumab treated patients with metastatic melanoma Opname en biodistributie van 89Zirconium-gelabeld ipilimumab in patienten met ge... not-yet-due
Not reported 2012-003710-13 C1-inhibitor improves efficacy of red blood cell transfusion in patients suffering from autoimmune hemolytic anemia – an open-labeled pilot trial 2021-09-29 due-trials
Completed, but no date, and reported results 2012-003981-42 Estrogen receptor and androgen receptor imaging in metastatic breast cancer patients bad-data
Completed, but no date Terminated 2012-004112-63 The Dutch STRIDER (Sildenafil TheRapy In Dismal prognosis Early-onset intrauterine growth Restriction) Trial The Dutch STRIDER (Sildenafil TheRapy In Dismal prognosis Early-onset intrauterine growt... bad-data
Ongoing 2012-004321-25 A phase II, single arm, multicenter study of nilotinib in combination with pegylated interferon α2b in patients with suboptimal molecular response or stable detectable molecular residual disease after... not-yet-due
Ongoing 2012-004892-37 N-Acetylcysteine in patients with Sickle Cell Disease. Reducing the incidence of daily life pain in patients with sickle cell disease not-yet-due
Ongoing 2012-004961-42 Measurement of tumor kinase inhibitor concentrations using PET imaging in patients with advanced solid malignancies Het meten van concentraties kinaseremmer in tumorlesies bij patienten met vergevo... not-yet-due
Ongoing 2012-005066-36 Effect of Growth Hormone replacement therapy on cardiovascular risk factors in adult patients with severe growth hormone deficiency: association with IGF-I concentration not-yet-due
Not reported 2012-005214-19 A randomized, double-blind, placebo-controlled trial of golimumab+methotrexate versus methotrexate alone in methotrexate-naïve patients with psoriatic arthritis Een gerandomiseerd, dubbel blind, pl... 2018-10-18 due-trials
Completed, but no date, and reported results 2012-005291-34 Perioperative intravenous insulin, GIK or GLP-1 treatment in DM Perioperatief intraveneus insuline, GIK of GLP-1 behandeling in DM bad-data
Completed, but no date, and reported results 2012-005332-29 Prevention of depression and poor physical function in older persons with vitamin D supplementation Preventie van depressie en matig lichamelijk functioneren bij ouderen met vitamine D-suppletie bad-data
Ongoing 2012-005447-25 The use of Rienso, an ultrasmall superparamagnetic particle of iron-oxide, as a MRI contrast agent to image inflammation in the atherosclerotic plaque not-yet-due
Ongoing 2012-005466-34 Therapeutic Vaccination against Human Papillomavirus Type 16 for the Treatment of Anal Intraepithelial Neoplasia in HIV+ Men not-yet-due
Ongoing 2013-000238-37 Treatment guided by detection of Minimal Residual Disease after allogeneic stem cell transplantation in Acute Myeloid Leukaemia not-yet-due
Completed, but no date, and reported results 2013-000381-11 Paracetamol or NSAID's in acute musculoskeletal syndromes Paracetamol of NSAID's bij acute musculoskeletale syndromen bad-data
Reported results 2013-000789-13 DALI: Vitamin D And Lifestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention - A European multicentre, randomised trial 2016-01-31 due-trials
Ongoing 2013-000801-21 Stimulation of the ovaries in women with breast cancer undergoing fertility preservation: alternative versus standard stimulation protocols; the STIM-trial De effectiviteit van hormoonstimulatie vo... not-yet-due
Ongoing 2013-000875-33 Prevention of Phantom Limb Pain After Transtibial Amputation (PLATA) - Randomized, double-blind, controlled, multi-center trial comparing Optimized intravenous pain control vs Optimized intravenous pa... not-yet-due
Ongoing 2013-001029-17 Efficacy and safety of trough level-based dose reduction during infliximab maintenance treatment in Crohn’s disease not-yet-due
Ongoing 2013-001034-18 Super ovulation in intrauterine insemination: FSH or Clomifene citrate not-yet-due
Completed, but no date Terminated 2013-001060-38 Pre-operative Decitabine in colon cancer: a proof of principal study Pre-operatief Decitabine bij patiënten met dikkedarmkanker bad-data
Not reported Terminated 2013-001722-25 Cholinesterase inhibitors to slow progression of visual hallucinations in Parkinson’s disease: a multi-center placebo-controlled trial (CHEVAL) 2018-09-27 due-trials
Ongoing 2013-001743-31 The cardiovascular effects of hyperoxia during and shortly after CABG surgery not-yet-due
Reported results 2013-002009-70 Quadrivalent HPV vaccination after effective treatment of Anal Intraepithelial Neoplasia in HIV+ men 2019-02-20 due-trials
Not reported Terminated 2013-002023-41 Image guided treatment optimalization with cetuximab for patients with metastatic colorectal cancer: IMPACT - CRC Optimalisatie van de behandeling van uitgezaaide dikke darmkanker met cetuximab mid... 2021-01-07 due-trials
Ongoing 2013-002091-41 Right vEntricular Dysfunction in tEtralogy of Fallot: INhibition of the rEnin-angiotensin-aldosterone system Rechterhartkamer dysfunctie bij tetralogie van Fallot: inhibitie van het Renine-angioten... not-yet-due
Completed, but no date, and reported results Terminated 2013-002106-31 The DANCE study: Duration of ANtibiotic therapy for CEllulitis bad-data
Exempt 2013-002370-51 Phase I/II study of LDE225 in combination with gemcitabine and nab-paclitaxel in patients with locally advanced or metastasized pancreatic cancer Fase I/II studie met LDE225 in combinatie met gemci... not-yet-due
Ongoing 2013-002563-25 Pilot study to determine the effect of fractionated radiotherapy on expression of pro-angiogenic factors in oeshophagus carcinoma Een pilot studie om het effect te onderzoeken van gefractioneerde r... not-yet-due
Exempt, with results Terminated 2013-002663-25 A phase I- IIa open-label clinical trial, evaluating the therapeutic vaccine hVEGF26-104/RFASE in patients with advanced solid tumors Een fase I-IIa klinische studie naar het therapeutisch vaccin h... not-yet-due
Not reported Terminated 2013-002670-40 Noninvasive Imaging of Vulnerable Inflammatory Coronary Plaque using Cardiac PET/CT in Humans: a feasibility study Onderzoek naar het gebruik van verschillende PET-tracers voor het vaststellen van ... 2018-11-15 due-trials
Ongoing 2013-002709-79 Mechanism of action study of anti-IL17 treatment in spondyloarthritis: Impact on cellular and molecular pathways of synovial inflammation and tissue remodeling. not-yet-due
Not reported 2013-002838-20 The effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) 2017-11-15 due-trials
Ongoing 2013-002860-19 The risk of cardiovascular disease in Ankylosing Spondylitis; A Single Center Cross-Sectional Study Evaluating The Association Between Inflammation In Ankylosing Spondylitis And Vascular Inflammation not-yet-due
Completed, report not yet due Terminated 2013-002884-24 Pessary or Progesterone to Prevent Preterm delivery in women with short cervical length Pessarium of progesteron ter preventie van vroeggeboorte in vrouwen met een korte cervixlengte 2023-09-08 not-yet-due
Ongoing 2013-002932-25 Multimodal treatment of perianal fistulas in Crohn's disease: seton vs anti-TNF vs advancement plasty not-yet-due
Ongoing 2013-003354-24 Influence of exogenous growth hormone administration on circulating levels of Klotho in healthy and CKD subjects not-yet-due
Not reported 2013-003658-26 Treat-to-target strategy for early RA patients in usual clinical practice: The COBRA Cohort Study 2018-12-18 due-trials
Ongoing 2013-003684-54 Analgesic efficacy of saphenous nerve blockade for outpatient knee anterior cruciate ligament surgery De effectiviteit van locale verdoving van de nervus saphenus voor pijnbestrijding bij kruisban... not-yet-due
Ongoing 2013-003733-15 The Dutch CSF and PET Biomarker Concordance of Alzheimer’s Disease pathology study De Nederlandse CSF en PET Biomarker Concordantie van Alzheimer pathologie studie not-yet-due
Reported results 2013-003949-41 Role of different phosphate binders on absorption of vitamin K, metabolism of matrix γ-carboxy-glutamaat (Gla) proteïne (MGP). Rol van verschillende fosfaatbinders t.a.v. absorptie van vitamine K, ... 2018-10-01 due-trials
Not reported 2013-003998-10 A randomized clinical trial investigating Lanreotide For output reduction in patients with high-output Enterocutaneous fistula 2022-05-29 due-trials
Completed, but no date, and reported results 2013-004024-11 New pharmacotherapeutic treatment options for crack-cocaine dependent people in the Netherlands: A double-blind, placebo-controlled randomized feasibility study of sustained release dexamphetamine bad-data
Completed, but no date, and reported results 2013-004111-42 Feasibility study of chemoradiation, TRAstuzumab and Pertuzumab in resectable HER2+ esophageal carcinoma Haalbaarheidsstudie van chemoradiatie, trastuzumab en Pertuzumab in resectable HER2 + slokd... bad-data
Ongoing 2013-004120-11 PI3K pathway analysis in tumor tissue and circulating DNA to obtain further insight in the efficacy of everolimus when combined with exemestane. A side-study protocol attached to standard treatment wi... not-yet-due
Reported results 2013-004635-69 A phase II study of obinutuzumab monotherapy in rituximab-refractory follicular lymphoma Obinutuzumab monotherapie voor rituximab-refractair folliculair lymfoom 2019-10-25 due-trials
Listed as ongoing, but also has a completion date 2013-004918-18 Optimising adalimumab treatment in psoriasis with concomitant methotrexate. 2020-06-04 bad-data
Ongoing 2013-005363-52 Intravenous immunoglobulin overtreatment in chronic inflammatory demyelinating polyneuropathy (CIDP) not-yet-due
Ongoing 2014-000047-33 The effect of high-resistance muscle strength training and vitamin D supplementation in persons with knee osteoarthritis Het effect van hoog-intensieve spierkrachttraining en vitamine D suppletie b... not-yet-due
Ongoing 2014-000124-14 Antibiotic prophylaxis to prevent wound infections following implant removal after foot, ankle and lower leg fractures. Antibioticaprofylaxe ter preventie van wondinfecties na verwijderen osteosynt... not-yet-due
Ongoing 2014-000219-15 Amyloid pathology in cognitively normal elderly subjects Amyloid pathologie in cognitief normale ouderen not-yet-due
Ongoing 2014-000304-96 Sentinel lymph node identification in colon cancer using a radioactive and fluorescent tracer not-yet-due
Ongoing 2014-000562-21 Amyloid-PET as a diagnostic marker in daily practice. Amyloid-PET als een diagnostische marker in de dagelijkse praktijk. not-yet-due
Ongoing 2014-001012-19 Effects of fingolimod on functional brain adaptation and clinical measures in multiple sclerosis Het effect van fingolimod op functionele breinadaptatie en klinische maten in multiple sclerose not-yet-due
Exempt, with results 2014-001333-88 A phase Ib/II study on the addition of Nab-paclitaxel (Abraxane) to capecitabine and oxaliplatin in the first-line treatment of metastastasized oesophagogastric carcinoma Een fase I/II onderzoek na... not-yet-due
Ongoing 2014-001438-27 The effect of bezafibrate on cholestatic itch not-yet-due
Not reported 2014-001546-25 Short versus extended antibiotic treatment with a carbapenem for high-risk febrile neutropenia in hematology patients with Fever of Unknown Origin: a randomized multicenter open-label non-inferiority ... 2019-08-05 due-trials
Listed as ongoing, but also has a completion date and reported results 2014-001561-27 Vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia: comparing one-hour infusions with bolus injections (the VINCA-study) Vincristine-geïnduceerde perifere neuro... 2022-02-01 bad-data
Ongoing 2014-001666-10 Local delivery of CER-001 in advanced plaques Proof-of-concept for apoA-1 as initiator of reverse cholesterol transport (LOCATION) Lokale afgifte van CER-001 in gevorderde plaques Conceptueel bewij... not-yet-due
Ongoing 2014-001816-20 Fractional CO2 laser assisted delivery of topical anesthetics: a randomized controlled pilot study Toediening van topicale anaesthetica met behulp van fractionele CO2-laser: een gerandomiseerde, ge... not-yet-due
Ongoing 2014-001988-12 Fractional CO2 laser assisted delivery of topical articaine and epinephrine solution vs. topical EMLA administration: a randomized controlled pilot study Toediening van topicale articaïne en epinef... not-yet-due
Ongoing 2014-002147-18 A randomized controlled double-blinded trial comparing the effect of on Demand ROcuronium boluses vs continuous infusion on rating of surgical and anesthesia conditions and need for reversal in Patien... not-yet-due
Reported results 2014-002178-35 A phase 4, monocenter, randomized, open label, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 8-week treatment with the glucagon-like peptide-1 receptor ... 2019-08-14 due-trials
Ongoing 2014-002514-23 Reduction Of Microvascular Injury Utilizing Sonolysis not-yet-due
Not reported 2014-002547-17 Grey matter microglial imaging with [18F]DPA-714 in progressive MS patients Beeldvorming van microglia in de grijze stof met [18F]DPA-714 bij progressieve MS patiënten 2016-01-21 due-trials
Not reported 2014-002569-32 Biomedical interventions for HIV prevention in MSM in Amsterdam: a demonstration project Biomedische interventies voor hiv preventie in MSM in Amsterdam: een demonstratieproject 2020-12-01 due-trials
Ongoing 2014-002794-11 Adjuvant hyperthermic intraperitoneal chemotherapy in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicenter trial Adjuvante hypertherme intraperit... not-yet-due
Completed, but no date 2014-002808-25 Immune phenotyping in chronic hepatitis C patients treated with Sofosbuvir and Daclatasvir combination with or without Ribavirin for 12 or 24 weeks -SODA study bad-data
Ongoing 2014-002827-87 Multicenter randomized controlled trial comparing Ferric(III)carboxymaltose infusion with oral iron suppletion in the treatment of preoperative anemia in colorectal cancer patients not-yet-due
Completed, but no date, and reported results 2014-002832-15 Ulipristal versus Gonadotropin-releasing hormone agonists prior to laparoscopic myomectomy: a double blind randomized controlled trial Ulipristal versus Gonadotropine-releasing hormoon agonists voo... bad-data
Ongoing 2014-002928-27 Observing Platelet Activability in a Once daily vs. a More frequent Aspirin intake regimen not-yet-due
Ongoing 2014-003148-11 Mechanism of action study of Ustekinumab treatment in psoriatic arthritis: Impact on cellular and molecular pathways of synovial inflammation and tissue remodeling not-yet-due
Ongoing 2014-003385-24 The Recall-study: Rivastigmine for ECT-induced Cognitive Adverse effects in Late Life Depression: a multicenter, randomized, double-blind, placebo-controlled, crossover trial De Recall studie: Riv... not-yet-due
Ongoing 2014-003468-19 The effects of hyperoxia on organ dysfunction and outcome in critically ill patients with SIRS Het effect van hyperoxie op orgaan dysfunctie en overleving in Intensive Care patienten met SIRS not-yet-due
Ongoing 2014-003469-10 The application of contrast-enhanced ultrasound to facilitate thrombolysis in patients with acute peripheral arterial occlusions. not-yet-due
Ongoing 2014-003680-38 Pharmacokinetics of two different high dose regimes of intravenous vitamin C in critically ill patients Farmacokinetiek van twee verschillende hoge doseerregimes van intraveneus vitamine C bij IC p... not-yet-due
Completed, but no date 2014-003932-38 Advanced imaging in laparoscopic HIPEC for peritoneal carcinomatosis of colorectal orgin to improve cytoreduction; a feasibility study bad-data
Ongoing 2014-004501-32 Infusion VErsus STimulation, a cost-effectiveness analysis of the treatment in advanced Parkinson's disease comparing Continuous Intrajejunal Levodopa Infusion to the traditional standard treetment De... not-yet-due
Ongoing 2014-004739-38 Follow-up of the FRUIT-RCT; aspirin resistance and cardiovascular risk factors in women after recurrent hypertensive disorders in pregnancy not-yet-due
Listed as ongoing, but also has a completion date 2014-005363-33 Reducing Micro Vascular dysfunction In revascularized STEMI patients by off-target properties of ticagrelor 2019-04-09 bad-data
Listed as ongoing, but also has a completion date 2014-005376-29 An open label interventional phase 4 study to evaluate efficacy, safety and mucosal healing of early versus late use of vedolizumab in Crohn's disease: the LOVE-CD study (LOw countries VEdolizumab in ... 2023-05-26 bad-data
Listed as ongoing, but also has a completion date 2014-005443-40 An open label interventional phase 4 study to Evaluate Efficacy, Safety and Mucosal Healing of early versus late use of vedolizumab in ulcerative colitis: the LOVE-UC study (LOw countries VEdolizumab ... 2020-08-10 bad-data
Not reported Terminated 2014-005611-16 Effect of Intravenous Administration of C1-inhibitor on Inflammation and Coagulation after Bronchial Instillation of House Dust Mite Allergen and Lipopolysaccharide in Allergic Asthma Patients 2019-10-23 due-trials
Listed as ongoing, but also has a completion date 2015-000276-10 FAST – Food Allergy Specific ImmunoTherapy A multinational phase IIb study to investigate the efficacy and safety of subcutaneous immunotherapy with a modified fish- parvalbumin given in single rising... 2017-03-31 bad-data
Listed as ongoing, but also has a completion date 2015-000555-24 Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Determine the Efficacy and Safety of Vedolizumab in Prevention of Endoscopic Recurrence of Crohn's Disease in Patients with Ileo-colo... 2022-10-26 bad-data
Ongoing 2015-000644-42 Laparoscopic advanced Imaging Techniques in Endometriosis therapy: LITE-study. A pilot trial. not-yet-due
Not reported 2015-001234-22 A randomized placebo-controlled study in patients with a Gallium-68 DOTATATE PET/CT positive, clinically non-functioning pituitary macroadenoma (NFMA) of the effect of Lanreotide autosolution on Tumor... 2021-05-26 due-trials
Ongoing 2015-002289-21 Parameters in fractional laser assisted delivery of topical anesthetics: role of laser type, laser settings, type of anesthetic and occlusion time not-yet-due
Ongoing 2015-002667-42 Sedation with propofol TCI during ERCP: Is the combination with esketamine more effective and safer than with alfentanil (SPEKA): A randomized controlled multicentre trial Sedatie met propofol TCI... not-yet-due
Reported results 2015-002729-21 The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study Comparing the cost-effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rh... 2021-01-29 due-trials
Ongoing 2015-003202-16 A randomized, double-blind, placebo-controlled study to compare the safety and immune effects of multiple doses of vitamin D3 in patients with allergic rhinitis/rhino-conjunctivitis caused by birch p... not-yet-due
Not reported 2015-003220-31 Low dose aspirin in the Prevention of Recurrent Spontaneous Preterm Labour – the APRIL study 2020-03-27 due-trials
Ongoing 2015-003293-32 Multicentre, Randomised, Placebo-Controlled Trial of Mebeverine in Children with Irritable Bowel Syndrome (IBS) or Functional Abdominal Pain - not otherwise specified (FAP-NOS) not-yet-due
Exempt Terminated 2015-003554-41 A phase I/II “minor histocompatibility antigen UTA2-1 loaded, PD-L silenced Dendritic cell vaccination trial after allogeneic Stem Cell Transplantation to improve the safety and efficacy of Donor Lym... not-yet-due
Ongoing 2015-003705-42 Longitudinal imaging of tau accumulation in the preclinical stages of AD Longitudinale beeldvorming van de accumulatie van tau in de preklinische stadia van de ziekte van Alzheimer not-yet-due
Ongoing 2015-003818-24 A phase 4, monocenter, randomized, double-blind, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 12-week treatment with the sodium-glucose linked transpor... not-yet-due
Exempt 2015-003862-10 A phase 1 and phase 2 study of daratumumab in combination with all-trans retinoic acid in relapsed/refractory multiple myeloma 2022-10-18 not-yet-due
Reported results 2015-004230-10 Validating in vivo quantification of tau with [18F]AV-1451 PET Het valideren van in vivo quantificatie van tau met [18F]AV-1451 PET 2018-11-08 due-trials
Ongoing 2015-004260-10 89Zirconium-labeled pembrolizumab as predictive imaging biomarker of response and toxicity in pembrolizumab treated patients with non-small-cell lung cancer – a feasibility study 89Zirconium gelabe... not-yet-due
Ongoing 2015-004745-70 Efficacy of intranasal ketamine on acute suicidality, a double blind randomized placebo-controlled trial (Ketamine Trial Amsterdam, KETA) Effectiviteit van intranasale ketamine op acute suïcidalit... not-yet-due
Ongoing 2015-004760-11 89Zirconium-labeled nivolumab and 18F-labeled anti-PD-L1 as predictive imaging biomarkers of response and toxicity in nivolumab treated patients with non-small-cell lung cancer – a feasibility study ... not-yet-due
Reported results 2015-004937-29 Towards early identification of response to CABAZItaxel in patients with metastatic castration-resistant prostate cancer: potential of 18F-Choline PET-CT (CABAZIPET). Vroegtijdig identificeren va... 2019-05-01 due-trials
Ongoing 2015-004998-33 Multicenter prospective trial after first or second unsuccessful treatment discontinuation in chronic myeloid leukemia estimating the efficacy of nilotinib in inducing the persistence of molecular rem... not-yet-due
Ongoing 2015-005260-41 Efficacy of optimized thiopurine therapy in ulcerative colitis. Effectiviteit van geoptimaliseerde thiopurine therapie in colitis ulcerosa. not-yet-due
Ongoing 2015-005765-23 Companion biomarker development for MEDI4736 treated non-small-cell lung cancer patients using 89Zirconium-labeled MEDI4736 – a feasibility study Biomarker ontwikkeling voor MEDI4736 in de behandel... not-yet-due
Completed, report not yet due 2015-005811-34 Pregnancy reLated Acute hyperTension INtervention Action: a randomized trial comparing labetalol and nicardipine in women with acute hypertension in pregnancy (Platina-trial) 2023-08-31 not-yet-due
Ongoing 2016-000345-31 Towards personalized dosing of natalizumab in multiple sclerosis Op weg naar een gepersonaliseerde behandeling met natalizumab in multiple sclerose not-yet-due
Ongoing 2016-001006-41 The Efficacy of TRH in Intensive Care patients; a dose finding study not-yet-due
Ongoing 2016-001332-35 A nationwide open-label multi-center prospective cohort study of nab-paclitaxel plus gemcitabine in patients with locally advanced pancreatic cancer Een open-label multicenter prospectief cohortstu... not-yet-due
Ongoing 2016-001353-41 Oxygenation of Affected Limbs in CRPS-I Patients not-yet-due
Ongoing 2016-001401-16 The SUGAR-DIP trial: Oral medication strategy versus insulin for diabetes in pregnancy De SUGAR-DIP trial: Orale medicatie strategie versus insuline voor diabetes gravidarum not-yet-due
Completed, report not yet due Terminated 2016-001797-15 A phase II/III study of high-dose, intermittent sunitinib in patients with recurrent glioblastoma multiforme Een fase II/III studie met intermitterend, hoge dosis sunitinib bij patiënten met een re... 2023-01-31 not-yet-due
Not reported Terminated 2016-001853-41 Intensive endoscopic therapy versus conventional treatment for untreated benign anastomotic strictures after esophagectomy: a pilot and randomized controlled trial 2019-04-05 due-trials
Completed, but no date 2016-002342-23 The cardiovascular dose-response to supplemental oxygen in healthy volunteers bad-data
Not reported Terminated 2016-002635-15 Study to Identify Factors associated with Resilience to Clinical Dementia at Old Age Studie naar de beschermende factoren voor dementie bij mensen boven de 90 jaar 2018-10-02 due-trials
Not reported 2016-002691-27 An open label exploratory analysis of the histological, immunological and microbiome changes of the colonic mucosa during treatment with tofacitinib for moderate-severe ulcerative colitis 2020-08-31 due-trials
Ongoing 2016-002965-67 An open, non-randomized, parallel-group pharmokinetic and -dynamic, investigator-initiated study on effects of obeticholic acid (OCA) in bile of patients with primary biliary cholangitis (PBC) and non... not-yet-due
Ongoing 2016-003052-70 Initial non-operative treatment strategy versus appendectomy treatment strategy for simple appendicitis in children aged 7-17 years old. APAC study not-yet-due
Reported results 2016-003245-29 Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after Roux-en-Y gastric bypass and Sleeve Gastrectomy 2020-11-06 due-trials
Ongoing 2016-003281-84 The Effect of UrsodeoXyCholicacid (UDCA) and ezetimibe on total faecal steRol ExcreTion and plasma lipid lEvels not-yet-due
Ongoing 2016-003495-53 Prostacyclin receptor agonist Selexipag in patients with pulmonary arterial hypertension and congenital heart disease Prostacycline receptor agonist selexipag in patiënten met pulmonale arteriële h... not-yet-due
Ongoing 2016-003594-17 Effects of a single denosumab injection on reduction of total contact cast treatment and consolidation of bonefractures caused by acute Charcotfoot in patients with diabetes mellitus (CHARCOT study... not-yet-due
Not reported 2016-003739-40 The effect of Iberogast on heartburn in patients with dyspepsia Het effect van Iberogast op pyrosisklachten bij patiënten met dyspepsie 2021-07-07 due-trials
Not reported Terminated 2016-003819-36 Combining SBRT and pembrolizumab in early stage non-small cellular lungcancer patients planned for surgery: exploring safety and immunological proof of principle. De combinatie van stereotactische... 2022-03-11 due-trials
Reported results Terminated 2016-004303-32 ASsesment of Platelet function and Inhibition in patients Recovering from severe INfection 2021-03-18 due-trials
Ongoing 2016-004545-91 Continuous use of Oral contraceptives as an alternative for long term Pituitary down-regulation with GnRH agonist prior to IVF/ICSI in Endometriosis patients: a randomised controlled trial (COPIE tria... not-yet-due
Ongoing 2016-004744-11 PDL-1 targeting in resectable oesophageal cancer: a phase IB feasibility study of Atezolizumab and chemoradiation (PERFECT) Haalbaarheidsonderzoek naar de behandeling van preoperatieve chemoradioth... not-yet-due
Ongoing 2016-004766-26 Intravenous immunoglobulins as early treatment in newly diagnosed idiopathic inflammatory myopathies (IMMEDIATE): a pilot study. not-yet-due
Ongoing 2016-004794-41 Arterial wall inflammation measured with 18F-FDG PET/CT in patients with statin intolerance before and after treatment with a PCSK-9 inhibitor not-yet-due
Exempt Terminated 2016-004827-22 A randomized, double-blind, placebo-controlled, double-dummy study to determine the safety/tolerability of a simultaneous subcutaneous treatment of BM41 and vitamin D 3 in patients with moderate to se... not-yet-due
Reported results 2017-000043-40 GLP-1 for bridging of hyperglycaemia during cardiac surgery: a randomized controlled trial 2018-09-30 due-trials
Reported results Terminated 2017-000137-31 Pulmonary Hypertension REversal in Clusters of Patients With Identical Pathobiological Substrates. 6-Mercaptopurine Proof-of-Concept Trial 2019-07-01 due-trials
Completed, report not yet due Terminated 2017-000169-60 A phase 2 study of nivolumab combined with daratumumab with or without low dose cyclophosphamide in relapsed/refractory multiple myeloma 2023-01-25 not-yet-due
Reported results 2017-000349-30 Effect of INtervention with DMR, GLP-1 and lifestyle intensification -in Subjects with insulin dePendent type 2 diabetes- on Insulin Requirement and mEtabolic parameters Effect van interventie met... 2020-12-16 due-trials
Completed, report not yet due Terminated 2017-000364-15 A randomized phase II/III study of pulsatile high-dose sunitinib versus TAS-102 in patients with metastatic colorectal carcinoma (mCRC). Gerandomiseerde fase II-III studie tussen sunitinib versus T... 2023-01-24 not-yet-due
Ongoing 2017-000724-10 Targeting esophageal cancer with HDL nanoparticles: an imaging study not-yet-due
Ongoing 2017-000841-28 Combined effects of SGLT2 inhibition and GLP-1 receptor agonism on food intake, body weight and central satiety and reward circuits in obese T2DM patients not-yet-due
Other 2017-001007-72 Atosiban versus placebo in the treatment of late threatened preterm birth (APOSTEL VIII). not-yet-due
Ongoing 2017-001025-41 Prevention of relapse with Levamisole as adjuvant therapy to corticosteroids in children with first episode of idiopathic nephrotic syndrome Preventie van recidief na eerste episode van idiopathisc... not-yet-due
Ongoing 2017-001438-25 A Study to Explore the Safety, Tolerability, Pharmacokinetic Profile, and Potential Efficacy of Guanabenz in Patients With Early Childhood Onset Vanishing White Matter (VWM) not-yet-due
Not reported 2017-001547-12 A phase 4, monocenter, randomized, double-blind, comparator-controlled, 3-armed parallel mechanistic intervention trial to assess the effect of 8-week empagliflozin (SGLT-2 inhibitor) monotherapy, fol... 2021-07-01 due-trials
Not reported Terminated 2017-001737-85 Efficacy of AlbenDazole to inDuce mUcosal healing in Patients with Crohn's disease on anti-TNF monotherapy Effectiviteit van albendazol voor het induceren van mucosale heling bij patiënten met de z... 2020-03-01 due-trials
Ongoing 2017-001840-37 ERtugliflozin triAl in DIabetes with preserved or reduced ejeCtion FrAcTion mEchanistic evaluation in Heart Failure: "ERADICATE-HF" not-yet-due
Ongoing 2017-002022-20 The effect of inspiratory oxygen fraction on the ratio of partial arterial oxygen pressure and inspiratory oxygen fraction (PaO2/FiO2 ratio) in mechanically ventilated patients with and without mild t... not-yet-due
Ongoing 2017-002079-24 Targeting the secondary bile acid glycodeoxycholic acid as therapeutic strategy in type 2 diabetes mellitus. Het aangrijpen van het secundaire galzout glycodeoxycholaat als therapeutische strategie... not-yet-due
Ongoing 2017-002478-37 Right Dose, Right Now: Randomized Clinical Trial Meteen de juiste dosis: gerandomiseerde klinische trial not-yet-due
Other 2017-002511-34 Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in CIDP not-yet-due
Ongoing 2017-002636-16 Cognitive impairment and functional reorganization in multiple sclerosis: The role of GABA and glutamate Cognitieve achteruitgang en functionele reorganisatie in multiple sclerose: de rol van GABA ... not-yet-due
Not reported 2017-003072-31 The effects of sex hormone administration on marrow and visceral adiposity 2021-12-17 due-trials
Not reported Terminated 2017-003766-27 The DREAMING study: Efficacy of low dose amitriptyline and mirtazapine for insomnia disorder: a double-blind, randomized, placebo-controlled trial in general practice 2022-06-28 due-trials
Exempt, with results Terminated 2017-003860-11 11C-erlotinib brain uptake in Diffuse Intrinsic Pontine Glioma imaged by PET 2018-06-01 not-yet-due
Not reported Terminated 2017-003975-80 Shorter treatment of catheter related urinary tract infections Kortere behandeling van catheter gerelateerde urineweginfecties 2019-10-22 due-trials
Ongoing 2017-004311-40 Tranexamic Acid to Prevent Operation in Chronic Subdural Hematoma Tranexaminezuur ter Voorkoming van een Operatie voor Chronisch Subduraal Hematoom not-yet-due
Ongoing 2017-004318-25 Early high-dose vitamin C in post-cardiac arrest syndrome. Vroege hoge dosis intraveneuze vitamine C na reanimatie. not-yet-due
Completed, report not yet due 2017-004424-29 Pharmacogenetics Use For Further treatment Improvement in childreN (PUFFIN) trial 2023-11-01 not-yet-due
Ongoing 2017-004675-31 A randomized Phase II study of second line treatment with liposomal irinotecan and S1 versus liposomal irinotecan and 5-fluorouracil in patients with metastatic pancreatic cancer who failed on first l... not-yet-due
Not reported Terminated 2017-004737-85 Alkaline Phosphatase to prevent ischemia reperfusion injury in living kidney transplantation 2020-09-10 due-trials
Exempt 2017-004751-23 A Phase 1b-2 study of Mitomycin-C / Capecitabine chemoradiotherapy combined with Ipilumimab and Nivolumab or Nivolumab monotherapy as bladder sparing curative treatment for muscle Invasive bladder Ca... not-yet-due
Ongoing 2017-004850-40 [18F]Fluoride PET-CT imaging for detection and monitoring of bone formation in spondyloarthritis [18F]Fluoride PET-CT beeldvorming voor het aantonen en monitoren van botformatie bij spondylartriti... not-yet-due
Ongoing 2017-005120-16 Ulipristal versus standard surgical treatment in symptomatic uterine fibroids Ulipristal versus standaard chirurgie in de behandeling van symptomatische uterine myomen not-yet-due
Completed, but no date 2018-000029-29 Extra energy for hearts with a genetic defect: ENERGY trial Extra energie voor harten met een genetische afwijking: ENERGY trial bad-data
Ongoing 2018-000748-24 Partial neuromuscular blockade to facilitate lung and diaphragm protective mechanical ventilation in ICU patients. A randomized controlled pilot study. not-yet-due
Ongoing 2018-001114-15 Positron emission tomography with macrophage targeting to select individuals at risk for rheumatoid arthritis. Positron emissie tomografie met een macrofagen tracer voor het selecteren van individ... not-yet-due
Not reported 2018-001339-33 A randomized, double-blind, placebo-controlled, study to determine the added value of vitamin D3 to treatment with subcutaneous immunotherapy in patients with moderate to severe allergic rhinitis/ rhi... 2019-07-15 due-trials
Ongoing 2018-001678-10 Tofacitinib: salvage therapy for patients with RCDII - a pilot study Tofacitinib: laatste redmiddel voor patiënten met RCDII - een pilot study not-yet-due
Ongoing 2018-001845-15 EvaluaTion of Clinical and laboratory outcomes of Rivaroxaban in short Bowel syndrome patients dEpending on Long term parenteral nutrition: a prospective cohort study (TINCRBEL study) Evaluatie va... not-yet-due
Completed, report not yet due 2018-002013-35 FES (16α-[18F]-fluoro-17β-estradiol)-PET: Towards a new standard to stage clinical stage II/III and recurrent, estrogen receptor positive (ER+) breast cancer? Pilot study to compare [18F]FES-PET and [... 2023-01-29 not-yet-due
Completed, but no date Terminated 2018-002064-15 Treatment of Perianal FIstulas in Crohn’s Disease: Surgical closure vs Anti-TNF bad-data
Reported results 2018-002170-52 TrimetaziDine as a Performance-enhancING drug in Heart Failure with Preserved Ejection Fraction 2021-11-22 due-trials
Listed as ongoing, but also has a completion date 2018-002277-22 AMYPAD Prognostic and Natural History Study (PNHS), an open label, prospective, multicentre, cohort study in individuals without dementia to evaluate the additional value of quantitative amyloid imagi... 2022-07-06 bad-data
Not reported 2018-002623-42 Vasospastic angina treatment by Endothelin Receptor Antagonism; a proof of concept study Vasospastische angina-behandeling door endotheline Receptorantagonisme; een proof of concept-studie 2021-11-27 due-trials
Not reported 2018-002643-28 Safety and tolerability of neoadjuvant nivolumab for locally advanced resectable oral cancer, combined with [18F]BMS-986192 / [18F]-FDG PET imaging and immunomonitoring for response prediction. Ve... 2022-01-06 due-trials
Exempt 2018-002752-33 A phase I/II trial towards the safety and efficacy of preemptive vaccination with PD-L silenced, minor histocompatibility antigen UTA2-1 peptide-loaded Dendritic Cells after Allogeneic Stem Cell Trans... not-yet-due
Ongoing 2018-002767-26 Liposomal iRInotecan, Carboplatin or oXaliplatin in the first line treatment of esophagogastric cancer: a randomized phase 2 study (LyRICX) Liposomaal iRInotecan, Carboplatin of o... not-yet-due
Ongoing 2018-003524-36 Randomized, Multicenter Study to Investigate the Efficacy of Dashboard Driven Individualized Dosing of Infliximab Compared To Standard Dosing During the Induction in Patients with Acute Severe Ulcerat... not-yet-due
Ongoing 2018-003594-95 Methotrexate to suppress immunogenicity to anti-tumor necrosis factor therapy in IBD patients with loss of response not-yet-due
Ongoing 2018-004153-24 Tubal flushing with oil-based contrast during HSG in subfertile women: Is early flushing effective and cost-effective as compared to delayed flushing? Is het verrichten van een HSG met olie contras... not-yet-due
Ongoing 2018-004192-12 Oil- based versus water-based contrast media for hysterosalpingography (HSG) in infertile women with unevaluated indications: a randomized controlled trial not-yet-due
Ongoing 2018-004323-37 Prevention of hepatic Encephalopathy by Administration of Rifaximin and Lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt: a multi-cent... not-yet-due
Ongoing 2018-004429-94 [18F]PEG-folate PET-CT imaging for monitoring of therapy response in rheumatoid arthritis patients [18F]PEG-folaat PET-CT beeldvorming voor de monitoring van response op therapie bij reumatoïde art... not-yet-due
Ongoing 2018-004466-34 Tau PET imaging in cognitively normal elderly subjects: A twin approach Tau PET-beeldvorming bij cognitief normale oudere proefpersonen: een tweeling benadering not-yet-due
Ongoing 2019-000133-39 A proof-of-concept study to evaluate 99mTechnetium radiolabeled Fucoidan as a diagnostic modality for thrombosis not-yet-due
Completed, but no date 2019-000730-19 A phase 4, monocenter, prospective, randomized, placebo-controlled, double-blind, cross-over mechanistic intervention trial to assess effect of 4-week Ertugliflozin (SGLT-2 inhibitor) therapy on renal... bad-data
Ongoing 2019-001202-14 CiPA Trial: Effect of Citalopram on chest pain in patients with achalasia not-yet-due
Ongoing 2019-001240-21 Exposure to orally administered antibiotics during the initial phase of infection in non-critically ill, febrile patients Blootstelling aan orale antibiotica tijdens de initiële fase van infectie b... not-yet-due
Not reported Terminated 2019-001518-40 Netherlands study of Optimal, PERsonalized Antidepressant use (OPERA-DISCONTINUATION) Nederlandse studie naar Optimaal gePERsonaliseerd Antidepressiva gebruik (OPERA-AFBOUW) 2022-08-12 due-trials
Completed, report not yet due 2019-001883-31 Microvascular Recovery using contrast Ultrasound in ST-elevation Myocardial Infarction in the ambulance (MRUSMI-Ambulance) 2024-01-09 not-yet-due
Not reported Terminated 2019-002138-35 Heavy menstrual bleeding in premenopausal women treated with direct oral anticoagulants - the MEDEA study 2022-11-01 due-trials
Ongoing 2019-002566-13 Personalized extended interval dosing of natalizumab in relapsing remitting multiple sclerosis not-yet-due
Ongoing 2019-002783-27 A 12-month, open-label, parallel-cohort study to evaluate the efficacy, safety and tolerability of Canakinumab in Kawasaki disease Een 12 maanden durende, open-label, parallel-cohort studie naar de... not-yet-due
Ongoing 2019-003127-38 Efficacy of add-on high dose simvastatin on markers for disease progression in MS patients treated with ocrelizumab and natalizumab (SIMSON), a phase II clinical trial. Effectiviteit van add-on hog... not-yet-due
Completed, but no date 2019-003141-15 A phase 4, monocenter, randomized, double-blind, placebo-controlled, 4-armed cross-over mechanistic intervention study to assess the renal hemodynamic effect of mono- and combination therapy with empa... bad-data
Ongoing 2019-003324-20 Saracatinib trial TO Prevent FOP Een onderzoek ter beoordeling van de veiligheid, verdraagbaarheid en effecten op abnormale botvorming van het onderzoeksgeneesmiddel AZD0530 (saracatinib) bij patië... not-yet-due
Ongoing 2019-003419-68 From fungus to virus, a phase 2a clinical trial investigating the safety and efficacy of terbinafine in chronic hepatitis B patients not-yet-due
Completed, report not yet due 2019-003454-83 Ipilimumab plus Nivolumab and ChemoRadiotherapy followed by Surgery in patients with resectable and borderline resectable T3-4N0-1 NSCLC 2023-11-30 not-yet-due
Ongoing 2019-003601-10 Treatment of Skin Severity in Ichthyosis with Hyperbaric Oxygen Therapy not-yet-due
Ongoing 2019-003698-24 Patient preference-based phosphate binder therapy in haemodialysis patients: a feasibility study on patient satisfaction Haalbaarheid van een behandelstrategie gebaseerd op voorkeuren van de patien... not-yet-due
Ongoing 2019-003740-77 Personalized prediction and regulation of 5-FU exposure Gepersonaliseerd voorspelling en regulatie van 5-FU blootstelling not-yet-due
Ongoing 2019-003766-41 The effect of Voxelotor on Cerebral Perfusion and Oxygenation (Coverage Study) not-yet-due
Completed, report not yet due 2019-004219-29 “Personalized AZithromycin/metronidAZole, in combination with standard induction therapy, to achieve a fecal microbiome community structure and metagenome changes associated with sustained remission i... 2023-02-27 not-yet-due
Completed, but no date 2019-004284-51 An exploratory study of durvalumab (MEDI4736) uptake during concurrent chemoradiotherapy in stage III NSCLC patients using 89Zr-labeled durvalumab PET bad-data
Ongoing 2019-004582-40 TIming of start of systemIc treatment for asymptomatic MEtastasized PANcreatic cancer (TIMEPAN): a randomized controlled multicenter trial not-yet-due
Ongoing 2019-004604-35 A phase 2 study of CC220 (iberdomide) combined with low-dose cyclophosphamide and dexamethasone in relapsed/refractory multiple myeloma (IberCd): ICON study Een fase 2 studie van iberdomide gecom... not-yet-due
Exempt 2019-004651-36 Glibenclamide Treatment for Cantú syndrome Glibenclamide behandeling voor Cantú syndroom 2023-11-21 not-yet-due
Ongoing 2019-004921-25 Safe shortening of antibiotic treatment duration for complicated Staphylococcus aureus bacteremia not-yet-due
Ongoing 2019-005021-79 Revised dosing recommendations of ciprofloxacin for patients with impaired renal function: a bioequivalence study. Vernieuwde aanbevolen doseringen van ciprofloxacine voor patiënten met een vermind... not-yet-due
Ongoing 2020-000165-16 A single-center, prospective, placebo-controlled, double-blind, randomized, cross-over mechanistic intervention study to investigate the effect of empagliflozin on kidney function in people with eithe... not-yet-due
Ongoing 2020-000449-15 Does Increasing Oxygen Nurture Your Symptomatic Ischemic Ulcer Sufficiently? not-yet-due
Completed, report not yet due 2020-001097-29 Rescue by radiotherapy and anti-CTLA4/PD-1 after failure of anti-PD-1 therapy in metastatic NSCLC patients, a proof-of-concept study. 2023-10-19 not-yet-due
Ongoing 2020-001101-22 Study to evaluate the efficacy and side effects of Envarsus in patients who had a kidney transplantation Onderzoek bij patiënten met een niertransplantatie naar werking en bijwerkingen van Envarsus not-yet-due
Reported results 2020-001236-10 COUNTER-COVID - Oral imatinib to prevent pulmonary vascular leak in Covid19 – a randomized, double --blind, placebo controlled, clinical trial in patients with severe Covid19 disease’ Effecten van ... 2021-02-01 due-trials
Ongoing 2020-001710-37 Intravenous immunoglobulin and prednisone vs. prednisone in newly diagnosed myositis: a double blind randomized clinical trial. Intraveneuze immunoglobulines als aanvullende behandeling bij pas ge... not-yet-due
Ongoing 2020-001952-16 Progesterone for Breast Development in Trans Women; Assessment of effects and safety -a pilot trial- not-yet-due
Ongoing 2020-002079-36 TGF-β And PDL-1 inhibition with Bintrafusp alfa in Esophageal Squamous Cell carcinoma combined with chemoradiation TheRapY (TAPESTRY) TGF-β en PDL-1 blokkade met Bintrafusp alfa in plaveiselcelcarc... not-yet-due
Ongoing 2020-002196-35 post-trial access cohort BUmetanide for Developmental DIsorders Post trial access Bumetanide voor ontwikkelingsstoornissen not-yet-due
Completed, report not yet due 2020-002695-12 Tofacitinib in the treatment of chronic, recurrent and/or antibiotic refractory pouchitis: a multi-omics approach Tofacitinib voor de behandeling van chronische, recidiverende, en/of antibiotica re... 2023-07-17 not-yet-due
Ongoing 2020-002864-30 Sulodexide for chronic heart failure: a proof of concept, randomized, placebo-controlled study not-yet-due
Ongoing 2020-002909-25 Blood-borne assessment of stromal activation in esophageal adenocarcinoma to guide tocilizumab therapy: a randomized phase II proof-of-concept study Behandeling van patiënten met resectabel oesofag... not-yet-due
Ongoing 2020-003437-38 Optical Coherence Tomography-Guided PCI with Single-Antiplatelet Therapy not-yet-due
Ongoing 2020-003601-66 The Effect of Crizanlizumab on Cerebral Perfusion and Oxygenation in Sickle Cell Patients not-yet-due
Ongoing 2020-004053-76 Effectiveness of methylphenidate in children and adults with Smith Magenis syndrome and attention-deficit/hyperactivity disorder: An N-of-1 series not-yet-due
Ongoing 2020-004294-48 Glioma: Reducing Anxiety by conSuming cannabinoidS – GRASS study. Treating anxiety with CBD in glioma patients – A randomized-controlled trial GRIP op spanning, bezorgdheid en piekeren, de GRASS st... not-yet-due
Ongoing 2020-004413-13 Dual-immunotherapy and short-course medium-dose radiotherapy, followed by surgery for tumor microenvironment modification in early stage NSCLC not-yet-due
Ongoing 2020-004995-17 Low dose iron chelation as TReatment of Oxidative stress in Sickle cell disease; TROS study Lage dosis ijzer chelatie therapie als behandeling van oxidatieve stress bij patienten met sikkel cel zie... not-yet-due
Ongoing 2020-005045-17 Resuscitation for repair of endothelial permeability in endotoxemia Resuscitatie voor herstel van endotheel permeabiliteit in endotoxemie not-yet-due
Ongoing 2020-005741-17 Hyperbaric OXygen therapy for ACute Acoustic Trauma not-yet-due
Ongoing 2021-000070-29 A Proof-of-Concept Study to Explore the Potential Efficacy of Deferiprone in Patients With Pelizaeus-Merzbacher disease (PMD) not-yet-due
Ongoing 2021-000469-33 A Prospective Multicenter Randomized Controlled, Open-label Study to Compare the Efficacy of Subcutaneous Infliximab Monotherapy with Subcutaneous Infliximab and Concomitant Immunosuppression in the T... not-yet-due
Ongoing 2021-000610-42 Dynamic and test-retest whole body [18F]FES PET imaging in patients with metastatic ER+ breast cancer. not-yet-due
Completed, report not yet due Terminated 2021-000720-36 oral PHA-022121 for the acute treatment and prophylaxis Of angioedema attacks in Patients with Acquired C1-Inhibitor Deficiency Oraal PHA-022121 voor de acute behandeling en profylaxe van angio-oed... 2023-03-16 not-yet-due
Ongoing 2021-000781-15 Neuroinflammation and post-infectious fatigue in individuals with and without Covid-19 Chronische vermoeidheidsklachten en neuro-inflammatie na een covid-19 infectie not-yet-due
Ongoing 2021-001123-40 18F-fluciclovine PET/CT and 18F-DCFPyL PET/CT in patients with biochemical recurrence of disease after radical prostatectomy: a prospective, single-centre, single-arm, comparative imaging trial 18... not-yet-due
Ongoing 2021-001174-29 Effectiveness of methylphenidate in adults with phenylketonuria and attention-deficit/hyperactivity disorder: An N-of-1 series Effectiviteit van methylfenidaat bij volwassenen met fenylketonurie en... not-yet-due
Ongoing 2021-001181-38 Anti-PD-1, Capecitabine, and Oxaliplatin for the first-line treatment of dMMR esophagogastric cancer (AuspiCiOus-dMMR): a proof-of-principle study Anti-PD-1, Capecitabine en Oxaliplatin voor de eer... not-yet-due
Reported results Terminated 2021-002288-24 Effect of citalopram on chest pain in patients with functional chest pain Het effect van citalopram op klachten van pijn op de borst bij patiënten met functionele retrosternale pijn. 2022-04-22 due-trials
Not reported Terminated 2021-002327-38 PREGCOVAC-19: the follow up of pregnant women who received COVID-19 vaccination in the Dutch national vaccination program 2022-02-28 due-trials
Not reported Terminated 2021-002505-10 Rescue Alkaline Phosphatase In Defense against all cause Acute Kidney Injury (RAPID-AKI) Rescue alkalisch fosfatase als behandeling van acute nierinsufficiëntie onafhankelijk van oorzaak (RAPID-AKI... 2022-07-27 due-trials
Ongoing 2021-002550-82 Effectiveness of ambroxol in children and adults with Gaucher disease 3: n-of-1 series not-yet-due
Ongoing 2021-003168-28 Impact of Triglyceride-Lowering on Inflammatory Activity in Patients with Hypertriglyceridemia Effect van triglyceride verlaging op inflammatoire activiteit in patienten met hypertriglyceridemie. not-yet-due
Ongoing 2021-003172-13 The renal and metabolic outcomes after sodium-glucose cotransporter 2 inhibitor in cardiac surgery – an open-label phase IV randomized controlled trial De perioperatieve renale en metabole uitkomst... not-yet-due
No trial status on register 2021-003250-23 Cannabidiol (Epidyolex) for behavioural problems in patients with Tuberous Sclerosis Complex, Sanfilippo and Fragile X Syndrome: an N-of-1 series Cannabidiol (Epidyolex) voor gedragsproblemen bij p... bad-data
Ongoing 2021-003677-66 Clemastine fumarate as remyelinating treatment in internuclear ophthalmoparesis and multiple sclerosis Clemastine fumaraat als remyeliniserende therapie in internucleaire oftalmoplegie en multiple... not-yet-due
Ongoing 2021-003823-14 Pharmacokinetic cross-over study of compounded chenodeoxycholic acid. not-yet-due
Ongoing 2021-003850-21 Precision psychiatry: Anti-inflammatory medication in Immuno-metabolic depression Precieze psychiatrie: Anti-inflammatoire medicatie bij immune-metabole depressie not-yet-due
Ongoing 2021-003913-21 A Prospective, Open-label Pilot Study to Evaluate Effector mechanisms of Hyperbaric Oxygen Therapy in Patients with Moderate-to-Severe Ulcerative Colitis: The PARADOX study not-yet-due
Ongoing 2021-004791-34 Efficacy, safety and cost-effectiveness of B cell tailored ocrelizumab versus standard ocrelizumab in relapsing remitting multiple sclerosis: a randomized controlled trial not-yet-due
Completed, report not yet due 2021-005344-30 TETRA-pilot: Testosterone in transgender women after vaginoplasty: a dose-finding and feasibility pilot study 2023-08-23 not-yet-due
Ongoing 2021-005474-25 DiEtary Sodium Intake effects on ertugliflozin-induced changes in GFR, reNal oxygenation and systemic hemodynamics: the DESIGN study, a randomized, placebo-controlled, cross-over study with ertugliflo... not-yet-due
Other 2021-005550-28 Less Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients not-yet-due
Ongoing 2021-005551-36 Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients with Cardiogenic Shock from Acute Myocardial Infarction: A Multicenter Randomized Tr... not-yet-due
Ongoing 2021-005688-36 Quinidine versus verapamil in short-coupled idiopathic ventricular fibrillation: An open label, randomized crossover pilot trial not-yet-due
Ongoing 2021-006072-16 Dual-AntiPlatelet Therapy strategies FOR elective PCI in a REAL-world setting Dubbele antiplaatjes therapie strategieën voor electieve percutane coronair interventies not-yet-due
Ongoing 2021-006108-34 Trial Examining Methods for Antidepressant Discontinuation Methoden om antidepressiva te stoppen vergeleken. De TEMPO-studie not-yet-due
Ongoing 2021-006333-19 EMECLO: the Electroconvulsive therapy vs. MEdication in patients with CLOzapine-refractory symptoms trial not-yet-due
Ongoing 2021-006767-14 Alkaline Phosphatase as treatment of Ischemia Reperfusion Injury to prevent delayed graft function Alkalische fosfatase als behandeling van ischemie-reperfusieletsel om vertraagde transplantaatfunc... not-yet-due
Ongoing 2022-000240-30 The chemopreventive effect of Lithium on adenoma development in patients with familial adenomatous polyposis (FAP); a pilot study Het preventieve effect van Lithium op adenoomvorming in patienten m... not-yet-due
Ongoing 2022-000241-32 Effectiveness of L-serine dietary supplementation in children with a GRIN2B loss-of-function mutation: n-of-1 series not-yet-due
Ongoing 2022-000404-35 Does the hematopoietic stem cell govern residual inflammatory cardiovascular risk in type 2 diabetes? not-yet-due
Ongoing 2022-000655-36 Evaluation of GeranylGeranylAcetone in heart failure with preserved ejection fraction not-yet-due
Ongoing 2022-000692-39 Safety, tolerability and immunogenicity of intradermal mRNA SARS-CoV2 vaccination in patients with Fibrodysplasia Ossificans Progressiva Veiligheid, tolerabiliteit en immunogeniciteit van intraderm... not-yet-due
Ongoing 2022-000837-17 Subcutaneous vedolizumab drug de-escalation using therapeutic drug monitoring in inflammatory bowel disease: a randomized controlled pilot study not-yet-due
No trial status on register 2022-001585-36 EffectS of L-glutaMIne on oxIdative stress, sickLE erythrocyte viability, inflammation and endothelial activity in sickle cell disease (SMILE trial) bad-data
Exempt 2022-001867-29 [68Ga]Ga-FAPI-46 positron emission tomography in pancreaticobiliary cancers: a pharmacokinetics, repeatability and diagnostic accuracy study. [68Ga]Ga-FAPI-46 positron emissie tomografie in pancre... not-yet-due
Ongoing 2022-002214-17 COLLISION RELAPSE trial - Recurrent colorectal liver metastases: repeat local treatment +/- neoadjuvantsystemic therapy - a phase III prospective randomized controlled trial COLLISION RELAPSE trial... not-yet-due
Ongoing 2022-002269-14 Dotatate to locate coronary plaques at high-risk of myocardial infarction not-yet-due
Ongoing 2022-002400-20 Feasibility of empagliflozin as treatment for idiopathic pulmonary arterial hypertension Haalbaarheidsstudie van empagliflozine als behandeling voor idiopathische pulmonale arteriële hypertensie not-yet-due
Ongoing 2022-002453-25 Preoperative sodium glucose cotransporter 2 inhibitors for prevention of postoperative acute kidney injury in cardiac surgery patients – a randomized, placebo-controlled, multi-centre, phase IV clinic... not-yet-due
Ongoing 2022-002481-32 Imaging inflammation in Alzheimer's Disease not-yet-due
Ongoing 2022-002751-19 FAPi-PET imaging of in vivo fibrosis in inflammatory bowel disease patients FAPi-PET beeldvorming van in vivo fibrose in patiënten met inflammatoire darmziekten not-yet-due
Ongoing 2022-003168-25 Oral ONCE Daily prophylaxis with PHA-022121 in Patients with Acquired C1-Inhibitor Deficiency Eenmaal daags oraal PHA-022121 ter profylaxe in patiënten met verworven C1-esteraseremmer deficiëntie not-yet-due
Ongoing 2022-003237-19 The difference in pharmacodynamic and pharmacokinetic profiles between Tentin and generic dexamphetamine in adults with attention deficit hyperactivity disorder, a double-blinded randomized crossover-... not-yet-due
Ongoing 2022-003866-19 The effect of low-dose rhythmic 17-β-estradiol administration on bone turnover in postmenopausal women Het effect van een lage dosis transdermaal 17-β-estradiol met ritmische toediening op botturno... not-yet-due
Ongoing 2022-004078-53 Specifying the anti-inflammatory effects of ziltivekimab with diverse imaging modalities and in-depth cellular phenotyping Specificeren van de anti-inflammatoire effecten van ziltivekimab met beh... not-yet-due