These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Reported results 2004-004736-30 Peginterferon alfa-2a and Ribavirin Combination Therapy in Patients with HBeAg-negative Chronic HBV Infection 2009-10-15 due-trials
Ongoing 2006-000701-35 Chemoreflex sensitivity during exercise with beta blockers not-yet-due
Ongoing 2006-002098-30 Efficacy of Inhaled RhDNase in Mechanically Ventilated Pediatric Patients with an Atelectasis not-yet-due
Ongoing 2006-002337-20 Efficacy of peripherally targeted inhaled rhDNase for persistent obstructive asthma in childhood not-yet-due
Ongoing 2006-004080-55 Stepwise Medical Treatment of Cushing’s Disease: a prospective open label multi-center trial with SOM230 mono- and combination therapy with dopamine agonists and ketoconazole not-yet-due
Ongoing 2006-004709-24 Mycophenolate sodium (Myfortic®) in the Treatment of Uveitis: a Pilot Study. not-yet-due
Ongoing 2006-004811-22 A prospective, randomized, double-blind comparison of 5 % against 1 % povidone-iodine solution in preoperative antisepsis for strabismus surgery in young children. not-yet-due
Ongoing 2006-005772-41 LIMIT: Lowering the Incidence of vascular complications with Metformin in patients with Impaired glucose tolerance and a recent TIA or minor ischemic stroke: a phase 2, randomized, controlled trial not-yet-due
Exempt 2006-006804-12 Levetiracetam (Keppra®) in neonates not-yet-due
Ongoing 2006-007091-15 Glivec (imatinib mesylate) in systemic sclerosis, a pilot study not-yet-due
Ongoing 2007-000467-23 Maternal and fetal haemodynamic response to Nifedipine tocolysis in normotensive pregnant women. not-yet-due
Ongoing 2007-000727-17 Maternal, uteroplacental and fetal haemodynamic effect of Nicardipine in severe pre-eclampsia. not-yet-due
Ongoing 2007-000935-25 ‘Peripheral targeting of inhaled rhDNase in stable CF patients.’ not-yet-due
Ongoing 2007-001170-92 Dexamethasone for postoperative pain relief following tonsillectomy in children not-yet-due
Ongoing 2007-002763-27 A multi-center, randomized, controlled trial with programmed introduction of Sirolimus-based, Calcineurin inhibitor free immunosuppression in recipients of non-heart-beating donor kidney grafts. not-yet-due
Ongoing 2007-003377-15 Chemoreflex sensitivity, exercise and beta agonists not-yet-due
Ongoing 2007-003537-16 Estetrol Therapy in Sjogren's Syndrome: An Open Proof of Concept Study not-yet-due
Ongoing 2007-005232-81 Wet-wrap treatment in children with atopic eczema using the wet-wrap method with diluted corticosteroids versus emollients not-yet-due
Ongoing 2007-005619-24 Morphine intravenous vs. Acetaminophen intravenous in neonates and young infants undergoing major non-cardiac surgery. not-yet-due
Completed, but no date, and reported results 2008-000053-35 A phase II study to assess engraftment and engraftment kinetics after double cord blood transplantation with a reduced-intensity conditioning regimen in patients eligible for allogeneic stem cell tran... bad-data
Ongoing 2008-000069-41 Regulation of colloid osmotic pressure during cardiopulmonary bypass in infants: prospective randomised trial not-yet-due
Completed, but no date, and reported results 2008-000424-86 Development and introduction of a pediatric liquid formulation of 6-mercaptopurine for treatment of leukemia bad-data
Ongoing 2008-000793-20 Sirolimus (Rapamune®) for the treatment of anti-Hu associated paraneoplastic neurological syndromes not-yet-due
Ongoing 2008-001827-76 The role of TSH in the human immune system, a clinical trial not-yet-due
Ongoing 2008-004114-28 Effectiveness of Diclofenac versus Paracetamol in primary care patients with knee osteoarthritis. not-yet-due
Ongoing 2008-004830-26 Optimization of electroconvulsive therapy (ECT) and continuation pharmacotherapy in major depressive disorder not-yet-due
Ongoing 2008-005619-16 Impact of anti-tumor necrosis factors antibodies treatment on fertility of inflammatory bowel diseases male patients not-yet-due
Ongoing 2008-005659-83 Second IVIg Dose in GBS patients with poor prognosis (SID-GBS trial) not-yet-due
Ongoing 2008-005814-28 Cost-effectiveness of viscosupplementation therapy for patients with osteoarthritis of the knee: a randomized clinical trial not-yet-due
Ongoing 2008-006889-29 A pilotstudy comparing systemic versus locoregional injection of radiolabelled somatostatin analogues in patients with neuroendocrine Gastro-Entero_Pancreatic (GEP) tumors. not-yet-due
Ongoing 2008-008251-42 Clinical and immunological effects of imiquimod and HPV-vaccination compared to imiquimod alone in female patients with Usual type VIN not-yet-due
Ongoing 2008-008293-31 Early introduction in the Netherlands of alglucosidase alfa manufactured in a 4000 liter bioreactor not-yet-due
Exempt, with results 2009-009457-13 A Phase I/II study of clofarabine in combination with cytarabine and liposomal daunorubicin in children with relapsed/refractory pediatric AML 2015-04-02 not-yet-due
Completed, but no date, and reported results 2009-010965-22 The effect of long-term simvastatin treatment on cognitive function and daily life in children with Neurofibromatosis 1: a one year randomized controlled trial bad-data
Completed, but no date, and reported results Terminated 2009-010999-19 Protein and Energy Interactions in Critically Ill Children bad-data
Ongoing 2009-011158-17 Additional treatment to primary PCI: effects of ischemic postconditioning and Exenatide. not-yet-due
Completed, but no date, and reported results 2009-011827-30 Cost-effectiveness of subcutaneous immunotherapy in adults with allergic rhinitis. bad-data
Ongoing 2009-012186-63 Landelijke Werkgroep voor Neuro-Oncologie trial (LWNO 0901) Randomized phase II study of Bevacizumab versus Bevacizumab plus Lomustine in patients with recurrent Glioblastoma: the BELOB trial not-yet-due
Ongoing 2009-013022-16 Effecten en bijwerkingen van opioïden: een studie naar de rol van farmacokinetische en farmacogenetische heterogeniteit. not-yet-due
Reported results 2009-014037-25 Bortezomib (Velcade): A feasibility and phase II study in childhood relapsed acute lymphoblastic leukemia Bortezomib (Velcade): Studio di fattibilita' e di fase II nella recidiva di leucemia lin... 2015-10-21 due-trials
Completed, but no date Terminated 2009-014268-20 VZV vaccination to prevent herpes zoster after transplantation bad-data
Ongoing 2009-014892-31 Morphine intravenous vs. Paracetamol intravenous in children on ECMO not-yet-due
Ongoing 2009-014922-40 Carfilzomib in combination with Thalidomide and Dexamethasone for remission induction and consolidation of Multiple Myeloma at first presentation not-yet-due
Ongoing 2009-017315-15 Multi Center Clinical trial of endovascular treatment of acute ischemic stroke in the Netherlands. Multi Center Clinical trial of endovascular treatment of acute ischemic stroke in the Netherlands... not-yet-due
Ongoing 2010-018498-39 VItamin D treatment Effect on retinal nerve fiber loss after Optic neuritis not-yet-due
Ongoing 2010-019019-39 'Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) as an outcome measure to evaluate the effectiveness of intra-articular hyaluronic acid for knee osteoarthritis’ not-yet-due
Ongoing 2010-019519-39 Efficacy of RAD001/everolimus in Autism and NeuroPsychological deficits in children with TSC (RAPIT-trial) Onderzoek naar behandeling van leer- en gedragsproblemen bij kinderen met Tubereuze Sclero... not-yet-due
Exempt 2010-019897-33 Selective D1 activation by addition of L-Dopa to antipsychotic treatment in patients with schizophrenia not-yet-due
Ongoing 2010-020303-69 Enzyme substitution in exocrine pancreatic insufficiency; Self administration against a fixed dose regimen. not-yet-due
Completed, but no date 2010-020332-19 Putting Resistance under the Microscope. (Weerstand onder de Loep) bad-data
Ongoing 2010-021437-30 Paracetamol (Acetaminophen) in Stroke 2 (PAIS 2): A randomized, placebo-controlled clinical trial of high-dose paracetamol in patients with acute stroke and a body temperature of 36.5°C or above P... not-yet-due
Ongoing 2010-021844-17 Perioperative esmolol infusion for haemodynamic stability during major vascular surgery. not-yet-due
Reported results 2010-022235-10 A Phase I/II study of Azacitidine (Vidaza®) in pediatric patients with newly diagnosed or relapsed high-grade pediatric MDS or JMML 2020-03-30 due-trials
Ongoing 2010-022655-29 Randomised open label cross-over study into the efficacy of RApamycin in children with Tuberous sclerosis complex with intractable Epilepsy (RATE-trial) not-yet-due
Ongoing 2010-023946-58 Immunogenicity and safety of an adjuvant hepatitis B vaccine (fendrix) compared to Engerix in non-responding HIV-infected patients not-yet-due
Ongoing 2011-000213-39 Intramuscular corticosteroid injections in hip osteoarthritis: a double-blinded randomized controlled trial not-yet-due
Ongoing 2011-002128-41 Accumulation of Nadroparin Used in Renal Insufficiency Assessed by anti-Xa levels not-yet-due
Completed, but no date Terminated 2011-002287-24 Massive blood loss in children during multiple trauma or major surgery: Fibrinogen therapy for massive blood loss during elective surgery for craniosynostosis repair, a double blinded randomized contr... bad-data
Ongoing 2011-003134-13 5-Aminolevulinic Acid PhotoDynamic Therapy for the treatment of premalignant disorders of the vulva. 5-Aminolevulinic acid fotodynamische therapie voor behandeling van premaligne aandoeningen van d... not-yet-due
Ongoing 2011-003264-77 A prospective trial with ketoconazole and octreotide combination therapy for treatment of Cushing’s disease. not-yet-due
Completed, but no date, and reported results 2011-003346-40 A phase II study in mCRPC on the pharmacodynamic effects of budesonide on cabazitaxel (Jevtana®): A randomised, open-label multicenter study: CABARESC bad-data
Reported results 2011-003815-46 Double blind placebo controlled randomized intervention study aiming at reducing dexamethasone related side effects in children with acute lymphoblastic leukemia (ALL). 2015-03-30 due-trials
Ongoing 2011-004201-25 The BOKITO-1B Study: Tenofovir DF Bone and Kidney Toxicity. Pharmacology in HBV monoinfected patients. De BOKITO-1B studie: Tenofovir DF bot- en niertoxiciteit. Farmacologie bij patiënten met hepa... not-yet-due
Ongoing 2011-004231-31 Randomized double blind multi-centre study of the effects on low-dose pegvisomant treatment in acromegalic subjects in whom the IGF1 levels has been normalized by long-acting somatostatin analogues ... not-yet-due
Ongoing 2011-004272-11 The BOKITO-2B Study: Tenofovir DF Bone and Kidney Toxicity. Incidence and reversibility in HBV-monoinfected patients. De BOKITO-2B studie: Tenofovir bot- en niertoxiciteit. Incidentie en reversib... not-yet-due
Ongoing 2011-004995-13 Endovascular renal sympathetic denervation versus spironolactone for treatment-resistant hypertension: a randomized, multicentric study Endovasculaire renale sympathicusdenervatue versus spironolac... not-yet-due
Ongoing 2011-005256-34 Sumatriptan non-responders: evaluation of a possible biomarker Sumatriptan non-responders: evaluatie van een mogelijke biomarker not-yet-due
Exempt Terminated 2011-005497-28 Pediatric Microdosing: elucidating age-related changes in oral absorption Pediatrische microdosering studie: ontrafelen van leeftijdgerelateerde veranderingen van orale absorptie 2017-12-31 not-yet-due
Ongoing 2011-006237-42 Optimization of exercise therapy in type 2 diabetes mellitus not-yet-due
Ongoing 2012-000645-13 Infliximab Top-down Study in Kids with Crohn’s disease not-yet-due
Ongoing 2012-001142-18 Efficacy and pharmacokinetics of a switch from a regimen consisting of emtricitabine, nevirapine and tenofovir to rilpivirine, emtricitabine and tenofovir in virologically suppressed HIV-1 infected pa... not-yet-due
Ongoing 2012-001416-27 Treatment of Cancer in the head and Neck: The Role of Hyperbaric Oxygen in Reducing Swallowing Problems Rol van hyperbare zuurstof therapie bij de vermindering van de slikklachten na bestraling not-yet-due
Ongoing 2012-001591-11 Symptomatic treatment of pollen related allergic rhinoconjunctivitis and the relation with asthma with children in the General practice Symptomatische behandeling van pollen gerelateerd allergische... not-yet-due
Ongoing 2012-002230-37 “Novel Approach to Detect the Detailed Effects of Vildagliptin on Beta-cell Dynamics in Patients with Early-onset Type 2 Diabetes” not-yet-due
Ongoing 2012-002503-17 Tobramycin nebulisation with I-neb (TONI) study in children with cystic fibrosis: pharmacokinetics and safety TONI studie: slimme vernevelaar voor tobramycine bij kinderen met cystic fibrosis: farm... not-yet-due
Ongoing 2012-003169-16 Immune monitoring to characterize T-cell responses of kidney transplant patients during co-stimulation blockade by belatacept not-yet-due
Ongoing 2012-003680-21 Putting Resistance under the Microscope II. ; A Randomized Controlled Trial on the effects of midazolam on the quality of postoperative recovery in patients Weerstand onder de Loep II; Een randomiz... not-yet-due
Ongoing 2012-004065-41 Comparative study of pharmacokinetics of amlodipine besilate oral liquid and tablets in healthy Dutch volunteers Vergelijkend onderzoek naar de farmacokinetiek van amlodipine besilaat orale drank e... not-yet-due
Ongoing 2012-005150-34 Dose response trial of IV immunoglobulin in chronic inflammatory demyelinating polyradiculoneuropathy not-yet-due
Listed as ongoing, but also has a completion date 2012-005226-29 Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease 2015-08-31 bad-data
Ongoing 2012-005330-10 Maternal pharmacokinetics and pharmacodynamics of nicardipine (iv) during treatment of severe hypertension in pregnancy. Maternale pharmacokinetiek en pharmacodynamiek van intraveneus nicardipine b... not-yet-due
Reported results 2012-005395-34 Prospective evaluation of the predictive value of a circulating tumor cell (CTC) sensitivity profile to Cisplatin chemotherapy in metastatic breast cancer patients 2019-02-28 due-trials
Ongoing 2012-005640-14 The effects of hormonal contraception on the HPA-axis functioning De effecten van hormonal anticonceptie op het functioneren van de HPA-as not-yet-due
Reported results Terminated 2013-000909-24 "OPTI-CLOT": Peri-Operative PharmacokineTIc-guided dosing of CLOTting factor in Hemophilia. "OPTIi-CLOT": Peri-OPeratieve farmacokineTIsch-gestuurde toediening van stollingsfactoren in hemofilie 2020-04-16 due-trials
Ongoing 2013-000956-16 Effect of low-dose ketamine on postoperative delirium in patients undergoing noncardiac surgery: a pilot study. Effect van ketamine op post-operatieve delier bij patienten die niet hartchirurgische... not-yet-due
Ongoing 2013-001525-10 Studying the metabolism of sorafenib (Nexavar®) by OATP1B blockage in adult cancer patients not-yet-due
Ongoing 2013-002026-22 Rectal and oral omeprazole treatment of gastroesophageal reflux in infants with esophageal atresia or congenital diaphragmatic hernia. A pharmacodynamic and pharmacokinetic study Rectale en orale... not-yet-due
Ongoing 2013-002122-23 The influence of electroencephalographic Narcotrend Index™- guidance of of propofol administration on recovery from procedural sedation for gastrointestinal endoscopy in paediatric patients De invl... not-yet-due
Completed, but no date, and reported results Terminated 2013-002744-89 Bioavailability of oral ciprofloxacin tablets and suspension in pediatric cancer patients De biologische beschikbaarheid van ciprofloxacine tabletten en suspensie in pediatrische kanker patienten bad-data
Listed as ongoing, but also has a completion date 2013-003405-26 The effect of Lamotrigine on cognitive deficits associated with Neurofibromatosis type 1: a phase II randomized controlled multi-centre trial (NF1-EXCEL) 2020-05-12 bad-data
Ongoing 2013-003603-19 Influence of an acidic beverage on the absorption of erlotinib Invloed van zure dranken op de absorptie van erlotinib not-yet-due
Ongoing 2013-003679-36 Postoperative Ileus reduction by NicOtine gum CHewIng after Operation: a pilot cohort study Reductie van postoperatieve ileus met behulp van het kauwen van nicotine kauwgum; pilot studie not-yet-due
Completed, but no date Terminated 2013-003842-18 Prevention of renal and bladder damage in children with spina bifida by means of early injections with Botulinum-Toxin-A (Botox): a pilot study. Preventie van nier- en blaasschade bij kinderen met ... bad-data
Ongoing 2013-004952-39 Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases The CHARISMA randomized multicenter clinical trial Neo-adjuvant... not-yet-due
Completed, but no date, and reported results 2013-004988-32 Rotterdam Observational Study in CIDP of Pharmacokinetics of Intravenous γ-globulin Rotterdamse observationele studie bij CIDP naar de farmacokinetiek van intraveneuze γ-globuline bad-data
Ongoing 2013-005323-17 Pharmacokinetic and pharmacodynamic properties of amlodipine oral solution in the pediatric population Farmacokinetische en farmacodynamische eigenschappen van amlodipine orale oplossing bij de ped... not-yet-due
Completed, but no date Terminated 2013-005376-17 Sandostatin therapy in sarcoidosis Sandostatine therapie bij sarcoïdose bad-data
Ongoing 2013-005479-42 Pilot study: Toxicity of oestradiol for adjuvant endocrine therapy in locally confined prostate cancer Pilot studie: Toxiciteit van oestradiol als adjuvante endorcriene therapie bij lokaal beperkte... not-yet-due
Ongoing 2013-005572-17 Optimizing propofol dosing for (preterm) newborn infants that need endotracheal intubation Optimaliseren van de dosis propofol voor sedatie bij endotracheale intubatie van (premature) neonaten not-yet-due
Listed as ongoing, but also has a completion date 2014-000178-20 Thyroid hormone analog therapy of patients with severe psychomotor retardation caused by mutations in the MCT8 thyroid hormone transporter: The Triac Trial. Behandeling met een schildklierhormoon a... 2017-07-28 bad-data
Not reported 2014-000675-13 Natalizumab (Tysabri®) for the treatment of anti-Hu associated paraneoplastic neurological syndromes 2020-11-25 due-trials
Ongoing 2014-001372-66 Tacrolimus monotherapy in immunologically low-risk kidney transplant recipients: a pilot randomized-controlled study. Tacrolimus monotherapie bij niertransplantatie patiënten met een immunologisch ... not-yet-due
Other 2014-001401-41 Targeting Antibiotics to Pseudomonas Aeruginosa in Small airways (TAPAS) study in patients with cystic fibrosis not-yet-due
Ongoing 2014-001406-17 Ventilator Associated Pneumonia: addition of Tobramycin Inhalation antibiotic treatment to standard IV antibiotic treatment not-yet-due
Reported results 2014-001587-35 Dexmedetomidine in awake implantation of neuromodulative systems. Dexmedetomidine bij wakkere implantatie van een neuromodulatief systeem. 2014-02-16 due-trials
Ongoing 2014-001919-39 Lengthening Adalimumab Dosing Interval in IBD patients in long term remission, the LADI study not-yet-due
Ongoing 2014-002219-41 A prospective single-centre double blind randomized study on the efficacy and safety of 4 weekly pasireotide LAR administration in combination with or without weekly pegvisomant in previously controll... not-yet-due
Ongoing 2014-002444-40 A Phase II study of Selinexor (KPT-330) combined with bortezomib and dexamethasone (SVd) for induction and consolidation for patients with progressive or refractory Multiple Myeloma. Inductie en co... not-yet-due
Exempt, with results Terminated 2014-003269-46 Pediatric microdosing midazolam: elucidating age-related changes in oral drug absorption not-yet-due
Completed, but no date Terminated 2014-003834-21 Effectiveness of penfluridol (oral long acting neuroleptic) as compared to second generation oral neuroleptics in psychotic disorder patients: an open label randomized controlled trial. Effectivite... bad-data
Ongoing 2014-004189-64 Hunting for the OFF-target properties of Ticagrelor on endothelial function and other circulating biomarkers in humans Alla ricerca delle propriet¿ fuori prescrizione del Ticagrelor: funzione endot... not-yet-due
Ongoing 2014-004432-18 Activity of trastuzumab based chemotherapy in metastatic breast patients with HER2-negative primary tumor but HER2 positive circulating tumor cells (CareMore-Trastuzumab) not-yet-due
Completed, but no date Terminated 2014-005454-19 The Dolutegravir Antiretroviral Mono-Therapy for HIV Trial De Dolutegravir mono-therapie voor HIV studie bad-data
Ongoing 2014-005702-37 Top-Down Infliximab Study in Kids with Crohn's disease (TISKids) Top-down Infliximab Studie bij Kinderen met de ziekte van Crohn (TISKids) not-yet-due
Completed, but no date, and reported results 2015-000964-33 Dexmedetomidine versus propofol in awake implantation of a neuromodulative system. Dexmedetomidine versus propofol tijdens de implantatie van een neuromodulatief systeem bad-data
Ongoing 2015-001043-37 Pharmacokinetics of Lorazepam Oral Liquid in Paediatric ICU Patients not-yet-due
Completed, but no date, and reported results Terminated 2015-001669-16 Duloxetine for chronic osteoarthritis pain; an important alternative? Duloxetine voor chronische pijn bij artrose; is het een belangrijk alternatief? bad-data
Ongoing 2015-001835-20 Morphine intravenous vs. paracetamol intravenous after cardiac surgery in neonates and infants. Morfine IV vs. paracetamol IV na cardiochirurgie in neonaten en kinderen not-yet-due
Completed, but no date, and reported results Terminated 2015-002209-12 Less opioids after major abdominal surgery in young infants using wound catheter infusion with local anesthetics: a randomized controlled trial. Is een wondcatheter met lokaal anesthetica opioid sp... bad-data
Not reported Terminated 2015-002820-20 Are alpha blockers effective in the treatment of bladder elimination problems in female patients with Multiple Sclerosis? Zijn alpha-blokkers effectief als behandeling van blaasledigingsproblemen b... 2020-04-07 due-trials
Ongoing 2015-002916-34 A Phase I/II study of Bosutinib in pediatric patients with newly diagnosed chronic phase or resistant/intolerant Ph+ Chronic Myeloid Leukemia, study ITCC-054/COG AAML1921 Een Fase 1-2 onderzoek m... not-yet-due
Ongoing 2015-003210-24 Grazoprevir (MK-5172) + Elbasvir (MK-8742) for the treatment of acute hepatitis C genotype 1/4. The Dutch Acute HCV in HIV Study (DAHHS-2) not-yet-due
Ongoing 2015-003551-22 STATIC IV: Efficacy of a loading dose of intravenous salbutamol in patients admitted to a PICU for severe acute asthma STATIC IV: Efficacy van een oplaaddosis intraveneus salbutamol in patiënten op... not-yet-due
Listed as ongoing, but also has a completion date and reported results 2015-004143-39 A Phase 3 randomised, double-blind, controlled trial of inhaled 7% hypertonic saline versus 0.9% isotonic saline for 48 weeks in patients with Cystic Fibrosis at 3-6 years of age in parallel with the ... 2020-12-22 bad-data
Ongoing 2015-004604-37 Aspirin provocation of patients with Systemic Mastocytosis Aspirine provocatie bij patiënten met systemische mastocytose not-yet-due
Ongoing 2015-005045-31 Switching to Tenofovir Alafenamide Fumarate or ABACavir in patients with Tenofovir Disoproxil Fumarate associated eGFR decline. A randomized clinical trial. Switchen naar tenofovir alafenamide fu... not-yet-due
Exempt 2015-005437-53 A phase 1B of crizotinib either in combination or as single agent in pediatric patients with ALK, ROS1 or MET positive malignancies Study ITCC 053 Studio di fase 1B su crizotinib in associazione ... not-yet-due
Ongoing 2015-005559-29 Within-patient variability in tacrolimus pharmacokinetics in renal transplant patients treated with different tacrolimus formulations. not-yet-due
Ongoing 2015-005700-28 An evaluation of the effectivity of the current treatment of uncomplicated urinary tract infections with fosfomycin. Een evaluatie van de doeltreffendheid van de behandeling van ongecompliceerde ur... not-yet-due
Completed, but no date 2015-005784-17 The effects of the proton pump inhibitor esomeprazole on the bioavailability of regorafenib in patients with a metastatic colorectal cancer (mCRC) or gastrointestinal stromal tumour (GIST). De eff... bad-data
Other 2016-000227-71 A phase I/II study of Inotuzumab Ozogamicin as a single agent and in combination with chemotherapy for pediatric CD22-positive relapsed/refractory Acute Lymphoblastic Leukemia not-yet-due
Ongoing 2016-000279-26 Trigeminovascular effects of propranolol in migraine treatment Trigeminovasculaire effecten van propranolol bij de behandeling van migraine not-yet-due
Ongoing 2016-000318-31 Ledipasvir and sofosbuvir for 8 weeks for the treatment of chronic hepatitis C genotype 4 in patients without cirrhosis. HepNed-001 study not-yet-due
Ongoing 2016-000406-11 The influence of electroencephalographic Narcotrend Index™ - guidance of propofol administration on recovery from procedural sedation for gastrointestinal endoscopy in children between 1 and 12 years not-yet-due
Completed, but no date Terminated 2016-000686-23 The Rotterdam Antiplatelet Therapy in Vascular Patients Study bad-data
Ongoing 2016-000859-27 Efficacy and mode of action of apremilast (Otezla) in moderate hidradenitis suppurativa. An exploratory pilot study. Effectiviteit en mode of action van apremilast in matig-ernstige hidradenitis s... not-yet-due
Completed, but no date 2016-001269-10 A pharmacokinetic study of Docetaxel and Prednisone in men with metastatic castration-resistant or hormone-sensitive prostate cancer. Een farmacokinetische studie van docetaxel en prednison bij man... bad-data
Reported results 2016-001597-15 Influence of a fatty beverage (Milk) on the absorption of erlotinib: a randomized, cross-over pharmacokinetic study (MERLOT-study) 2019-12-27 due-trials
Ongoing 2016-001875-57 Desmopressin and FVIII concentrate combination treatment in non-severe hemophilia A patients undergoing minor interventions Desmopressine en FVIII-concentraat combinatiebehandeling in niet-ernstige... not-yet-due
Ongoing 2016-002287-14 Death rattle in the dying phase: is prophylactic treatment useful? Reutelen in de stervensfase: is profylactische behandeling zinvol? not-yet-due
Ongoing 2016-002383-13 Umbilical cord blood transplantation in high-risk hematological patients using stemregenin-1 expanded hematopoietic stem cells. A feasibility study focussing on engraftment and hematopoietic recovery.... not-yet-due
Reported results 2016-002724-83 A phase IIa randomized, placebo controlled, double blinded study to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral ther... 2018-11-27 due-trials
Ongoing 2016-002859-19 Withdrawing off-label antipsychotics in people with intellectual disabilities: why does it fail? Antipsychotica afbouwen bij mensen met een verstandelijke beperking: waarom lukt het niet? not-yet-due
Ongoing 2016-002993-11 A single arm phase 2 multicenter study determining the response to Cabazitaxel in metastatic prostate cancer (mCRPC) patients with AR-V7 positive circulating tumor cells (CTCs) Fase 2 multicentrisc... not-yet-due
Ongoing 2016-003428-21 Non-inferiority multicentre randomized controlled trial comparing short versus standard course postoperative antibiotic treatment for complex acute appendicitis Non-inferiority, multicenter gerando... not-yet-due
Completed, but no date, and reported results 2016-004008-71 The effect of curcumin and piperine on the pharmacokinetics of tamoxifen in patients with estrogen receptor positive breast cancer ‘the ELDORADO study’ Het effect van kurkuma en piperine op de farm... bad-data
Ongoing 2016-004299-24 Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk score - a feasibility study not-yet-due
Listed as ongoing, but also has a completion date 2017-000421-13 Newborns with Congenital Diaphragmatic hernia: inhaled Nitric Oxide versus intravenous Sildenafil: an international randomized controlled trial 2023-09-01 bad-data
Ongoing 2017-000949-53 REduce BlAdder CAncer REcurrence in patients treated for upper urinary tract urothelial carcinoma (REBACARE Trial) Verminder blaaskankerrecidief bij patiënten die worden behandeld voor urotheelcarc... not-yet-due
Ongoing 2017-000976-27 Biomarker discovery study to identify patients with advanced urothelial cancer benefitting from pembrolizumab treatment Een fase 2 onderzoek naar nieuwe biomarkers die voorspellen welke patiënten m... not-yet-due
Ongoing 2017-001284-20 The effects of the proton pump inhibitor esomeprazole on the bioavailability of afatinib (Giotrif®) in patients with non-small cell lung cancer (NSCLC) 'the BIO-GIO study' Het effect van protonpomp... not-yet-due
Ongoing 2017-001466-21 Multicenter Randomized CLinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands. The effect of periprocedural MEDication: heparin, antiplatelet agents, both or neither. ... not-yet-due
Completed, but no date, and reported results 2017-001525-40 Effectiveness of different strengths of topical steroids: providing evidence for a better treatment strategy in children with atopic dermatitis in general practice. Effectiviteit van verschillende ... bad-data
Ongoing 2017-001665-25 Formoterol-beclomethasone in patients with bronchiectasis: a randomized, double-blind, placebo-controlled trial (Forza study) not-yet-due
Completed, but no date Terminated 2017-001681-24 Avoiding tacrolimus under- and overexposure by using a new dosing algorithm for pediatric renal transplant recipients Het voorkómen van onder- en overdosering van tacrolimus bij kinderen met een ni... bad-data
Ongoing 2017-002470-40 Observational study of the effects of probenecid on the pharmacokinetics and pharmacodynamics of sorafenib (PROSORA-study) Een observationele studie naar de effecten van probenecid op de farmacoki... not-yet-due
Ongoing 2017-002837-48 HIV Eradication by combining Agents to reverse Latency in vivo (HEAL-1): a randomized controlled trial. not-yet-due
Ongoing 2017-003115-20 Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: a prospective randomised multicenter double-blind placebo-controlled clinical trial not-yet-due
Ongoing 2017-003535-11 The added value of the H2-antagonist ranitidine in premedication regimens during paclitaxel treatment Evaluatie van de meerwaarde van ranitidine als anti-allergiemiddel bij paclitaxel chemotherapie not-yet-due
Ongoing 2017-004465-27 The effects of the proton pump inhibitor esomeprazole alone or in combination with Coca-Cola on the absorption of Capecitabine in patients with colorectal cancer or other solid tumours ' the COCA stud... not-yet-due
Ongoing 2017-004677-14 Dose IndividualizAtion of Beta-lactam and fluOroquinoLone AntiBiotics in ICU patients: to TDM or not to TDM and the effects on Outcome (DIABOLO-study) not-yet-due
Ongoing 2017-004735-37 Can Acetaminophen Ease the Heartbreak of Social Rejection? not-yet-due
Completed, report not yet due 2017-005124-24 Therapeutic Drug Monitoring guided tamoxifen dosing: a feasibility study in patients with hormone positive breast cancer Therapeutic Drug Monitoring gestuurde tamoxifen dosering: een haalbaarheidss... 2023-10-07 not-yet-due
Ongoing 2018-000011-25 Avoiding tacrolimus under- and overexposure by using a new dosing algorithm for renal transplant recipients Het voorkomen van onder- en overdosering van tacrolimus met een nieuw doseer algoritme not-yet-due
Ongoing 2018-001631-46 Implementation of pharmacokinetic-guided dosing of DDAVP and VWF-containing concentrates in von Willebrand disease Implementatie van farmacokinetisch gestuurd doseren van DDAVP en VWF-bevattende s... not-yet-due
Ongoing 2018-001696-21 Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk score - a randomized controlled trial not-yet-due
Reported results 2018-002119-81 Carriage of S. aureus and interaction with the nasal microbiome Dragerschap van S. aureus en interactie met het nasale microbioom 2020-09-01 due-trials
Ongoing 2018-002764-94 Adjuvant vaccination against HPV in surgical treatment of CIN lesions, a Randomised Controlled Trial Vaccinatie tegen HPV bij behandeling van CIN afwijkingen. Een RCT. (VACCIN studie) not-yet-due
Other 2018-002863-24 Intralesional steroid injections to prevent refractory strictures in patinets with esophageal atresia - a randomized controlled trial not-yet-due
Ongoing 2018-002914-10 FUnctional selection of advanced breast cancer patients for Talazoparib treatment Using the REpair Capacity (RECAP) test: The FUTURE trial not-yet-due
Not reported 2018-003222-92 Dendritic cells loaded with allogeneic tumor cell lysate (PheraLys™) in surgically resected pancreatic cancer patients (REACtiVe Trial) 2023-01-26 due-trials
Ongoing 2018-003869-33 Implementation of pharmacokinetic-guided dosing of prophylaxis in hemophilia patients. Implementatie van farmacokinetisch gestuurd doseren van profylaxe bij hemofilie patienten. not-yet-due
Ongoing 2018-003954-26 CYP3A4*22 genotype-guided dosing of TKIs in cancer patients: a new way of personalized therapy Op basis van CYP3A4*22 genotype doseren van tyrosine-kinase remmers bij patiënten met kanker: een nieu... not-yet-due
Ongoing 2018-004013-41 Hepatic arterial infusion pump chemotherapy in patients with unresectable intrahepatic cholangiocarcinoma not-yet-due
Ongoing 2018-004091-35 Improving Treatment Options for Somatostatin Type 2 Receptor Negative Neuroendocrine Tumor Patients not-yet-due
Ongoing 2018-004239-63 Botulinum toxin (BOTOX®) to prevent post-operative pancreatic fistula in patients who undergo distal pancreatectomy. PROFIT study. not-yet-due
Ongoing 2018-004338-13 Short term clinical efficacy of topical treatment with clindamycin-benzoyl peroxide gel compared with clindamycin lotion in mild to moderate Hidradenitis Suppurativa Effectiviteit van lokale behand... not-yet-due
Ongoing 2018-004724-11 Clinical effectiveness of 2 treat to target strategies, mimicking standard care compared to early secukinumab for the treatment of Moderate to Severe Psoriatic Arthritis: a parallel group randomised c... not-yet-due
Not reported 2019-000216-29 Safety and efficacy of the addition of IMM-101 Heat-Killed Whole Cell Mycobacterium obuense to standard stereotactic radiotherapy in locally advanced pancreatic cancer patients (LAPC-2 trial). 2021-09-21 due-trials
Completed, report not yet due 2019-000276-41 Study on the effects of an OCT2/MATE1 substrate (metformin) and inhibitor (cimetidine) on the exposure of trifluridine/tipiracil (Lonsurf®) in patients with metastatic colorectal cancer (mCRC). Stu... 2023-05-11 not-yet-due
Exempt 2019-000657-31 Adoptive therapy with TCR gene-engineered T cells to treat patients with MAGE-C2-positive melanoma and head and neck cancer. not-yet-due
Ongoing 2019-000852-32 A preliminary study of Low Dose Naltrexone for the induction of remission in patients with mild to moderate Crohn’s Disease that failed conventional treatment: The LDN Crohn study. Een preliminair... not-yet-due
Ongoing 2019-001317-16 The TRAIN study: TRAmetinib In Neurofibromatosis type 1 related symptomatic plexiform neurofibromas De TRAIN studie: TRAmetinib voor Neurofibromatose type 1 gerelateerde pleximorme neurofibromen not-yet-due
Completed, report not yet due 2019-001425-26 Rotterdam Edoxaban Leaflet Evaluation in Patients after Transcatheter Aortic Valve Implantation Rotterdam Edoxaban Klepblad evaluatie bij patienten na een percutane aortaklep vervanging 2024-02-29 not-yet-due
Ongoing 2019-001854-24 Long-term outcomes in immunologically low-risk kidney transplant recipients using tacrolimus. Extension study of: Tacrolimus monotherapy in immunologically low-risk kidney transplant recipients: a pil... not-yet-due
Ongoing 2019-002020-33 Pentoxifylline dose optimization in neonatal sepsis. not-yet-due
Ongoing 2019-002910-37 Study on the pharmacokinetic interaction between green tea and tamoxifen in patients with breast cancer. “the TEA study” Studie naar de farmacokinetische interactie tussen groene thee en tamoxifen... not-yet-due
Ongoing 2019-003416-30 Guided by Light: Optimizing Surgical Excision of Oral Cancer Using Real-time Fluorescence Imaging Geleid door licht: Tumor-gerichte fluorescente stoffen helpen bij het volledig wegsnijden van e... not-yet-due
Other 2019-003666-41 Doxapram versus placebo in preterm newborns: an international double blinded multicenter randomized controlled trial. Doxapram versus placebo in premature neonaten: een internationaal, multicenter... not-yet-due
Ongoing 2019-003812-30 Primovist CT: proof of concept Primovist contrastmiddel: bruikbaar ook voor CT? not-yet-due
Ongoing 2019-003966-42 Adjuvant hepatic arterial infusion pump chemotherapy after repeat hepatectomy for patients with recurrent colorectal liver metastases without a history of extrahepatic disease – a phase II study not-yet-due
Ongoing 2019-004148-31 The PREDMETH trial: Effectiveness of methotrexate versus prednisone as first-line therapy for pulmonary sarcoidosis – A randomized controlled trial not-yet-due
Reported results 2019-004854-27 The influence of UGT inhibition on endoxifen exposure in cancer patients treated with tamoxifen: A proof of concept study. “The PROTAM study” De invloed van UGT remming op endoxifen blootstelling ... 2020-10-24 due-trials
Ongoing 2020-000433-40 Treatment of vascular stiffness in patients with autosomal dominant polycystic kidney disease Behandeling van vaatstijfheid bij patiënten met autosomaal dominante polycysteuze nierziekte not-yet-due
Ongoing 2020-000627-40 Azole-echinocandin combination therapy for invasive aspergillosis. A randomized pragmatic superiority trial (IA-DUET) not-yet-due
Reported results 2020-000823-38 Study on the pharmacokinetic interaction between cabazitaxel and darolutamide in metastatic castration-resistant prostate cancer (mCRPC) patients. Studie naar de farmacokinetische interactie tussen... 2021-11-10 due-trials
Ongoing 2020-001527-14 COVID-19: addition of azithromycin to chloroquine treatment COVID-19: toevoegen van azitromycine aan behandeling met chloroquine not-yet-due
Ongoing 2020-002672-12 Frontotemporal dementia Imaging of Neuroinflammation, Degeneration and Microglia-Related Effects not-yet-due
Ongoing 2020-002802-21 PeRsonalIzed MEdicine in Rheumatoid Arthritis (PRIMERA trial): a multicenter, single-blinded, randomized controlled trial comparing usual care with a tailor-made approach Behandeling op maat: Feit ... not-yet-due
Ongoing 2020-003214-12 A national randomized placebo-controlled double-blind multicenter trial of LT4/LT3 combination therapy in patients with autoimmune hypothyroidism. Een nationaal gerandomiseerde dubbel-blind placebo... not-yet-due
Ongoing 2020-003228-18 Intralesional bleomycin treatment of keloids using an electronic pneumatic jet injector: a double-blind randomized, placebo-controlled trial with split-lesion design Intralesionale bleomycine behan... not-yet-due
Ongoing 2020-003474-45 The STELLAR trial: Fluorescence-guided surgery in laryngeal- and hypopharyngeal cancer: a feasibility trial de STELLAR studie: fluorescentie geleide chirurgie bij strottenhoofd kanker: een haalbaa... not-yet-due
Ongoing 2020-003605-55 Combination of chemoTherapy aNd chemoradioTherapy for adenocarcinoma of the OESophagus and gastro-oesophageal junction with oligometastatic disease not-yet-due
Ongoing 2020-003890-23 The nephroprotective effect of short hydration during cisplatin treatment in head and neck cancer patients. Het nefroprotectieve effect van kort hydreren tijdens cisplatin chemotherapie bij patiënt... not-yet-due
Ongoing 2020-003945-13 Safety and efficacy of IMM-101 combined with stereotactic radiotherapy in patients with limited MEtastatic PANcreatic Cancer (MEPANC-1) not-yet-due
Ongoing 2020-005141-16 Perioperative versus adjuvant FOLFIRINOX for resectable pancreatic cancer: the PREOPANC-3 study. not-yet-due
Completed, report not yet due 2020-005271-12 Rediscovery of metformin for the chronic disabling auto-inflammatory disease hidradenitis suppurativa Herontdekking van metformine als behandeling voor de chronische huidziekte hidradenitis suppura... 2023-08-22 not-yet-due
Exempt 2020-005427-36 A multicenter, open label non-randomized phase I/II dose escalation study with extension cohort to determine the safety, tolerability and immune modulating effects of the therapeutic LRPAP1 synthetic ... not-yet-due
Ongoing 2020-005445-16 Fasting before live kidney donation, effect on donor wellbeing and postoperative recovery Preoperatief vasten voor levende nierdonatie, effect op donor welzijn en postoperatief herstel. not-yet-due
Other 2020-005450-18 SPACe 2 STAR : Safety and pharmacokinetics of antipsychotics in children 2. Studying TDM in An RCT not-yet-due
Ongoing 2021-000058-24 Administration of immune checkpoint inhibitors through an elastomeric pump. A patient preference study and cost analysis. Toediening van immune checkpoint inhibitors via een elastomeer pomp. Een ... not-yet-due
Ongoing 2021-000444-22 Differences in coagulation between fresh frozen plasma and Solventdetergent plasma in pediatric congenital heart surgery not-yet-due
Ongoing 2021-000515-24 Vaccination Against Covid in Primary Immune Deficiencies Covid-19 vaccinatie in primaire immuundeficienties not-yet-due
Ongoing 2021-000640-21 Long-term pain modulation by intravenous esketamine in Complex Regional Pain Syndrome: a non-inferiority study Lange-termijn pijnmodulatie met intraveneuze esketamine bij Complex Regionaal Pijnsynd... not-yet-due
Exempt 2021-000864-32 A Phase I-II study of virus neutralizing antibodies against SARS-CoV-2. A focus on convalescent plasma and hyperimmune anti-SARS-CoV2 immunoglobulines Een fase I-II studie over virus neutraliserend... not-yet-due
Ongoing 2021-001707-32 Nivolumab dose optimization in patients with a complete, partial or stable response (NIVOPTIMIZE-trial) Optimalisatie van de nivolumab dosering bij patienten na het bereiken van een complete, parti... not-yet-due
Completed, but no date 2021-003327-15 An open-label, 8-week, proof of concept trial on thymosin-α1 (thymalfasin) in the treatment of primary antibody deficiency (PAD) associated mood disorders (TIDAM18). Een open-label 8-weken proof-of... bad-data
Ongoing 2021-004015-11 Investigator led, double-masked, multicenter, randomized clinical trial for the comparison of Atropine 0.5% versus Atropine 0.05% eye drops for the prevention of myopia progression in Dutch children. ... not-yet-due
Ongoing 2021-004131-84 Chronotherapy in Inflammatory Arthritis (ChronIA trial): a randomized controlled trial comparing the effectiveness of morning and evening dosing of tofacitinib extended-release Chronotherapie in ... not-yet-due
Ongoing 2021-006013-11 Hyperbaric Oxygen Therapy for Pyoderma gangrenosum As a New Treatment Strategy Hyperbare Zuurstoftherapie voor pyoderma gangrenosum als nieuwe behandel mogelijkheid not-yet-due
Ongoing 2021-006481-21 Personalized tacrolimus treatment for pediatric kidney transplant recipients by using a dosing algorithm and a once-daily tacrolimus formulation Gepersonaliseerde tacrolimus dosering door gebruik t... not-yet-due
Ongoing 2022-000355-37 Nivolumab during active surveillance after neoadjuvant chemoradiation for esophageal cancer: SANO-3 study not-yet-due
Ongoing 2022-000514-33 CHemotherapy And Sequential ImmunoTherapy for locally advanced urothelial cancer: the CHASIT study Chemotherapie en sequentiële immunotherapie voor lokaal gevorderde urotheelkanker: de CHASIT-studi... not-yet-due
Ongoing 2022-001093-55 COATS study: genetic Clopidogrel response testing to finetune the antithrombotic regimen in (D)OAC Treated patients undergoing PCI not-yet-due
Exempt 2022-002194-28 Phase I/II study to determine the safety, immunogenicity and efficacy of Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination (HEB-PEP-Study) not-yet-due
Ongoing 2022-002384-30 Reduction of blood loss in pediatric osteotomies around the hip - A randomized placebo-controlled trial with tranexamic acid – not-yet-due
Ongoing 2022-002426-28 Predicting an accurate tamoxifen dose: a feasibility study in patients with hormone positive breast cancer Het voorspellen van de juiste dosering tamoxifen: een haalbaarheid studie in patienten met... not-yet-due
Ongoing 2022-002560-73 SWITCH ON: Analysing the immunogenicity of additional booster vaccinations in healthcare workers. not-yet-due
Ongoing 2022-002648-35 Prospective Analysis of Pharmacokinetic Infliximab Data in pediatric CD patients Prospectieve analyse van pharmacokinetiek van Inflximiab data in kinderen met inflammatoire darmziekten not-yet-due
Ongoing 2022-002673-28 Safe Stop IPI-NIVO Trial: Early discontinuation of nivolumab upon achieving a (confirmed) complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first... not-yet-due
Other 2022-003287-25 Intralesional steroid injections to prevent refractory strictures in patients with esophageal atresia - a randomized controlled trial Lokal steroidinjektion i anastomosstriktur efter esofagusatresi... not-yet-due
Ongoing 2022-003451-34 INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701 INTRUSION: Het ontrafelen van de intumorale FK/FD relatie van SAR408701 not-yet-due
Ongoing 2022-003792-41 A randomized phase II trial of docetaxel or cabazitaxel with or without darolutamide in men with metastatic castration-resistant prostate cancer. not-yet-due