These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Reported results 2004-002569-19 The effects of systemic vitamin D administration on production of interleukin-10 by peripheral blood T cells in asthmatics and controls. 2008-08-01 due-trials
Reported results 2005-000381-39 Efficacy and Safety of Memantine Hydrochloride, a low affinity antagonist to N-Methyl-D-Aspartate (NMDA) type receptors, in the prevention of cognitive decline and disease progression in older people ... 2009-02-09 due-trials
Reported results 2005-003382-16 Pilot randomised controlled trial of methotrexate for chronic inflammatory demyelinating polyradiculoneuropathy (RMC trial). 2008-03-04 due-trials
Reported results Terminated 2005-003732-22 Pilot study of 5 Azacitidine in the treatment of MDS/AML with high risk (chromosome 7 and/or complex cytogenetic abnormality) 2014-10-22 due-trials
Reported results 2005-005330-12 Omega-3 Fatty Acids Supplementation for Adolescent Boys with Attention Deficit Hyperactivity Disorder : a double-blind, randomized controlled trial 2007-12-20 due-trials
Reported results 2006-000105-38 A definitive multi-centre pragmatic randomised controlled double-blind trial of the clinical and cost effectiveness of mirtazapine and sertraline versus placebo for the treatment of depression in deme... 2010-10-07 due-trials
Reported results 2006-000106-24 Using genotype to tailor prescribing of nicotine replacement therapy: a randomised controlled trial assessing impact upon adherence 2008-10-09 due-trials
Reported results 2006-000395-32 The effect of COX-2 Inhibition on Reducing Central Sensitisation of Pain in Osteoarthritis 2011-03-29 due-trials
Reported results 2006-002099-16 The effect of milk thistle extract (Legalon) versus tea on serum iron increase after a meal containing non-haem iron in hereditary haemochromatosis 2006-10-16 due-trials
Reported results Terminated 2006-002330-38 Randomised Trial of Anti-CD20 in C4d+ Chronic Allograft Nephropathy 2017-03-09 due-trials
Reported results 2006-003327-36 Evaluation of the efficacy of colchicine with and without betamethasone mouthwash in the management of recurrent aphthous stomatitis 2011-01-13 due-trials
Other 2006-004470-26 Triple Negative breast cancer Trial. A randomised phase III trial of carboplatin compared to docetaxel for patients with metastatic or recurrent locally advanced ER-, PR- and HER2- breast cancer not-yet-due
Completed, but no date, and reported results Terminated 2006-004971-37 Adalimumab for psoriasis patients who are non-responders to etanercept: An open-label study bad-data
Reported results Terminated 2006-005407-33 The effect of long-term iron treatment on serum NTBI and plasma isoprostanes in anaemic women versus an anaemic control group 2006-12-20 due-trials
Reported results 2006-007042-18 Improved Diagnosis of Congenital Heart Disease by MRI using Vasovist - CHD Vasovist 2009-07-04 due-trials
Reported results 2007-000497-23 Do sulphponylureas preserve cortical function during hypoglycaemia in patients with type 1 diabetes and hypoglycaemia unawareness? 2013-02-22 due-trials
Reported results 2007-001172-36 Donepezil and Memantine in moderate to severe Alzheimer's Disease 2011-03-07 due-trials
Reported results 2007-001190-28 Randomised controlled trial of tumour-necrosis-factor inhibitors against combination intensive therapy with conventional disease modifying anti-rheumatic drugs in established rheumatoid arthritis 2011-12-14 due-trials
Ongoing 2007-001448-33 A multi-centre, double-blind, randomised, placebo-controlled trial using CD133 enriched bone marrow cells following primary angioplasty for acute myocardial infarction with central core laboratory ana... not-yet-due
Reported results 2007-004298-24 A cluster randomised trial of different strategies of antibiotic use to reduce the incidence and consequences of chest infection in acute stroke patients with swallowing problems. 2014-09-18 due-trials
Reported results 2007-004897-26 Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer's disease - MAIN-AD 2012-03-31 due-trials
Reported results 2007-005091-13 Phase II study of sorafenib in malignant mesothelioma previously treated with platinum-based chemotherapy 2012-10-12 due-trials
Reported results 2007-005464-26 The role of inflammatory biomarkers in pathophysiology of cardiovascular dysfunction in systemic inflammatory conditions- Part II 2012-03-12 due-trials
Reported results 2007-005534-36 The effect of Exenatide on satiety, metabolic parameters and regional brain activation in response to nutrient ingestion in Type 2 diabetes. 2011-01-05 due-trials
Reported results 2008-001865-28 The Relationship between Osteoporosis and Aortic Calcification in Postmenopausal Women 2014-10-29 due-trials
Reported results 2008-002244-42 Does 1-alpha,25-dihydroxyvitamin D3 (calcitriol) enhance corticosteroid activity in steroid refractory asthma? A randomised control trial to test whether active vitamin D can improve the clinical res... 2012-09-11 due-trials
Reported results Terminated 2008-002336-15 The effect of prednisolone versus hydrocortisone as glucocorticoid replacement therapy on hypoglycaemia frequency in people with Type 1 diabetes and adrenal insufficiency: a pilot study. 2017-09-20 due-trials
Reported results 2008-002599-86 A prospective open randomised controlled trial of women diagnosed with premature ovarian failure (POF) to investigate the effects of active treatment with HRT (hormone replacement therapy) or COCP (co... 2013-03-22 due-trials
Reported results Terminated 2008-004895-39 Quantitative Assessment of Myocardial Perfusion with Magnetic Resonance Using an Intravascular Contrast Agent 2011-11-24 due-trials
Reported results 2008-006891-31 A randomised placebo-controlled trial of Lithium carbonate in Amyotrophic Lateral Sclerosis (LiCALS) 2012-02-08 due-trials
Reported results 2008-006947-38 A randomised double-blind placebo-controlled pilot study of D-cycloserine-augmented exposure therapy in adolescents with obsessive-compulsive disorder 2012-12-13 due-trials
Reported results 2008-008342-20 Genetically determined brain abnormalities in Down’s Syndrome.- towards a treatment: A randomised, single-blind, placebo-controlled trial of lithium carbonate in Down’s Syndrome (DownsLit). 2011-12-31 due-trials
Reported results Terminated 2009-009154-25 The effect of a humanised monoclonal anti-IgE antibody (omalizumab) on disease control and bronchial mucosal inflammation in non-atopic (“intrinsic”) asthma 2013-07-12 due-trials
Reported results Terminated 2009-010808-28 Role of Non-invasive test in detecting fibrosis in chronic hepatitis B patients 2013-02-07 due-trials
Reported results 2009-013020-23 A Pilot study of cognitive enhancer and cognitive training combination – Testing a therapeutic paradigm for cognitive impairment in schizophrenia 2012-10-29 due-trials
Reported results 2009-015837-55 Double-blind, 36 month, placebo-controlled trial of mifepristone on cognition in alcoholics 2016-06-24 due-trials
Reported results 2009-016300-23 Pilot double blind randomised placebo controlled crossover trial of Hyoscine for the treatment of Clozapine induced nocturnal sialorrhoea. 2011-06-16 due-trials
Reported results 2009-016523-61 18F-fluoride PET for Early Non-invasive Assessment of Cortical Bone Formation 2012-02-15 due-trials
Reported results Terminated 2009-017098-40 Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failure (DEC-MDS) 2014-08-14 due-trials
Reported results 2010-018285-23 Effect of active vitamin D treatment on arterial stiffness and albuminuria in patients with type 2 diabetes and stage 3 chronic kidney disease 2018-04-01 due-trials
Reported results Terminated 2010-019656-41 Effects of Zoledronic Acid on arterial calcification and arterial stiffness in women – a co-twin randomised double blind, placebo-controlled parallel group, clinical trial 2014-10-21 due-trials
Reported results 2010-020738-24 Optimising Treatment With Tumour Necrosis Factor Inhibitors In Rheumatoid Arthritis: Is Dose Tapering Practical In Good Responders? A “Proof Of Principle” And Exploratory Trial. (OPTTIRA) 2014-07-07 due-trials
Reported results 2010-020841-29 The role of anti-IgE (omalizumab) in the management of severe recalcitrant paediatric atopic eczema 2017-08-31 due-trials
Reported results 2010-022184-35 A pragmatic randomised double-blind trial of Antipsychotic Treatment of very LAte-onset Schizophrenia-like psychosis: The ATLAS Trial 2016-12-14 due-trials
Reported results 2010-023122-21 Pro-Bono 2- A prospective study of loss of bone mineral density in patients with HIV over time: implications for clinical practice and therapeutic options: Vitamin D sub study. 2014-05-09 due-trials
Reported results Terminated 2011-000123-33 Evaluation of the feasibility of modulating and measuring endogenous neurogenesis with erythropoietin (rhEPOα) to expedite recovery after stroke 2014-04-04 due-trials
Reported results Terminated 2011-001088-28 Feasibility, efficacy and acceptability of injected buprenorphine as treatment for opiate users who persist in injecting illicit heroin through opiate maintenance treatment 2020-01-10 due-trials
Not reported 2011-003025-10 Effect of active vitamin-D treatment on left ventricular hypertrophy in patients with type-2 diabetes and stage-3 chronic kidney disease. 2020-05-29 due-trials
Reported results 2011-004220-34 A randomised phase II trial of [18F]fluorothymidine and the standard tracer [18F]Fluorodeoxyglucose in the assessment of systemic therapy response in triple negative breast cancer and their utility co... 2017-08-23 due-trials
Reported results Terminated 2011-005218-13 Rationalisation of antipsychotic drug use in older people, using [18F]-Fallypride PET 2016-02-04 due-trials
Reported results 2012-000344-10 Adjunctive Rifampicin to Reduce Early mortality from Staphylococcus aureus bacteraemia: a randomised controlled trial 2017-01-18 due-trials
Reported results 2012-000517-37 A pilot study of Concerta XL in adult offenders with ADHD 2015-02-23 due-trials
Exempt, with results 2012-001394-87 A prospective phase I/II study to evaluate allogeneic mesenchymal stromal cells for the treatment of skin disease in children with recessive dystrophic epidermolysis bullosa. 2014-12-11 not-yet-due
Reported results 2012-002193-31 A Randomised, Double-blind, Single-centre, Controlled Trial of Low Dose Intradermal Allergen Immunotherapy in Adults with Seasonal Allergic Rhinitis 2014-08-27 due-trials
Reported results 2012-002237-11 Effectiveness of Adaptive Opioid Agonist Maintenance Pharmacotherapy and Behavioural Therapy for Opioid Use Disorder. 2013-04-02 due-trials
Reported results 2012-004078-24 Intravitreal Tissue Plasminogen Activator (tPA), Perfluoropropane (C3F8), and Ranibizumab for Neovascular Age-Related Macular Degeneration and Submacular Haemorrhage (TAPAS): A Randomized, Double-Mask... 2019-11-15 due-trials
Other 2012-004308-36 A randomized controlled clinical trial to determine if a combined screening /treatment programme can prevent premature failure of renal transplants due to chronic rejection in patients with HLA antib... not-yet-due
Reported results 2012-005500-18 A pharmacokinetic study: ranibizumab, aflibercept and the effect of vitrectomy 2019-07-15 due-trials
Reported results 2012-005592-13 Mechanisms of Exercise Benefit with Intravenous Iron in Chronic Heart Failure: The Ferric Iron in Heart Failure (FERRIC HF) II Trial 2016-12-20 due-trials
Reported results Terminated 2013-000240-26 Cannabidiol as an add-on therapy in treatment-refractory psychotic disorders 2015-08-07 due-trials
Reported results 2013-000397-30 Minocycline in Alzheimer's disease efficacy trial:The MADE trial 2018-04-16 due-trials
Reported results Terminated 2013-002584-25 Naltrexone Enhanced Addiction Treatment (NEAT): A randomised controlled trial of the clinical and cost-effectiveness of extended-release naltrexone and oral naltrexone. 2017-04-21 due-trials
Reported results 2013-003144-23 Pregnancy And chronic hypertension: NifeDipine or labetalol as Antihypertensive treatment 2016-05-18 due-trials
Listed as ongoing, but also has a completion date 2013-003413-18 Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept. 2021-01-13 bad-data
Other 2013-004042-42 A study to investigate the potential renoprotective role of sodium-glucose transporter-2 (SGLT-2) antagonist Dapagliflozin in Type 2 diabetic patients with diabetic nephropathy not-yet-due
Other 2013-004704-19 Globifer Forte® Oral Haem and Non-haem Iron Supplementation in Heart Failure: A Randomised, DoubleBlind, Placebo Controlled, Double Dummy, Part Mechanistic. not-yet-due
Reported results 2013-004708-20 A placebo controlled single centre double blind randomised trial to investigate the efficacy of rifaximin versus placebo in improving systemic inflammation and neutrophil malfunction in patients with ... 2016-07-29 due-trials
Reported results 2014-002639-32 A randomised, double-blind, placebo-controlled, parallel-group trial of Vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis (DFEND) Neuroprotection... 2019-12-20 due-trials
Exempt 2014-003025-18 In Vivo Generation of Optimal Tumour Antigen-specific Anticancer Immune Responses, by Vaccination with Human Telomerase Reverse Transcriptase (hTERT) Peptides, in Combination with Specific Adjuvants a... 2019-07-30 not-yet-due
Reported results 2014-004478-41 Phase III trial in IntrahepaTic CHolestasis of pregnancy (ICP) to Evaluate urSodeoxycholic acid (UDCA) in improving perinatal outcomes 2018-11-28 due-trials
Exempt, with results 2014-004500-30 A phase I/II study evaluating allogeneic mesenchymal stromal cells in adults with recessive dystrophic epidermolysis bullosa 2017-07-12 not-yet-due
Listed as ongoing, but also has a completion date 2014-004557-14 Prospective randomised marker-based trial to assess the clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation 2022-06-20 bad-data
Exempt, with results 2014-004884-19 Phase I study of lentiviral-mediated COL7A1 gene-modified autologous fibroblasts in adults with recessive dystrophic epidermolysis bullosa (RDEB) 2018-03-13 not-yet-due
Other 2014-005193-11 METformin And Longevity (METAL): A window of opportunity study investigating biological effects of metformin in localised prostate cancer not-yet-due
Other 2015-000456-15 The prevention of pre-term birth in women who develop a short cervix. A multi-centre randomised controlled trial to compare three treatments; cervical cerclage, cervical pessary and vaginal progester... not-yet-due
Reported results Terminated 2015-000549-21 MAGnetic versus STAndard technique for sentinel node biopsy in breast cancer compared in a Randomised controlled trial 2017-02-20 due-trials
Listed as ongoing, but also has a completion date and reported results 2015-002013-29 A Randomised Controlled Trial Assessing the Effectiveness, Safety and Cost-effectiveness of Methotrexate versus Ciclosporin in the Treatment of Severe Atopic Eczema in Children: The TREatment of Sever... 2023-03-15 bad-data
Reported results 2015-003413-26 Understanding the molecular basis for the use of adjunctive anti-inflammatory treatment in treatment resistant depression: a stratified, randomised, placebo-controlled, experimental medicine study usi... 2019-12-17 due-trials
Other 2015-003609-41 The renoprotective effects of Ursodeoxycholic acid in patients with type 1 diabetes and albuminuria not-yet-due
Reported results 2015-004064-11 BETTER-B (Feasibility) BETter TreatmEnts for Refractory Breathlessness: A feasibility study of the use of mirtazapine for refractory breathlessness 2017-12-13 due-trials
Reported results 2015-004271-78 Randomised controlled trial of the short term effects of OROS-methylphenidate on ADHD symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder 2019-08-27 due-trials
Reported results 2015-004527-32 Pilot randomised controlled trial of SITAgliptin for Depressive Symptoms in type 2 diabetes 2019-08-08 due-trials
Other 2016-000775-24 CXCR2 inhibition: a novel approach to treating coronary heart disease not-yet-due
Other 2016-001637-27 A randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression. not-yet-due
Other 2016-001758-17 Effect of Lixisenatide on arterial stiffness in patients with diabetic nephropathy not-yet-due
Other 2016-001876-31 Feasibility of the safe withdrawal of inhaled corticosteroids in patients with mild to moderate COPD prescribed outside guidelines (SWAP) not-yet-due
Other 2016-001877-34 Improving understanding of Heroin Overdose Testing: diamorphine dose-escalation testing in a treated population not-yet-due
Reported results Terminated 2017-000177-37 Low-dose IL-2 to expand endogenous regulatory T cells and achieve tolerance in liver transplantation 2019-01-30 due-trials
Other 2017-002248-34 FInCH Study: A randomised feasibility study comparing fluoride interventions to prevent dental decay in older people in care homes. not-yet-due
Reported results 2017-003629-13 A Prospective, randomised placebo controlled feasibility trial of Faecal Microbiotica Transplantation in cirrhosis 2019-10-17 due-trials
Other 2017-004667-13 Effect of Iron (III) Isomaltoside 1000 on Cardiac Energetics in Anaemic and Non-anaemic Patients with Symptomatic Chronic Heart Failure and Iron Deficiency: The Ferric Iron in Heart Failure (FERRIC-HF... not-yet-due
Other 2018-000003-16 Prevention of Gestational Diabetes in Obese Pregnant Women; a Proof of Principle Study Targeting Early Pregnancy Intervention to Women at Risk not-yet-due
Other 2018-003573-97 A randomised, placebo controlled trial of psilocybin in treatment resistant depression: A feasibility study not-yet-due
Reported results Terminated 2018-003852-19 An Open Label, Non-Randomised, Phase IV Clinical Trial to Determine the Transfer of Apixaban and Rivaroxaban in Breast Milk Following Oral Administration 2020-07-15 due-trials
Reported results Terminated 2018-003893-29 Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or without sleep behaviour intervention in treatment naive children with rolandic... 2020-09-23 due-trials
Other 2018-004460-63 Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO): An Open Label Randomised Controlled Trial of Injectable Depot Maintenance Buprenorphine versus Standard-Of-Care Oral Maintenance Opioid... not-yet-due
Listed as ongoing, but also has a completion date 2019-002001-21 BETTER-B: BETter TreatmEnts for Refractory Breathlessness. An International, Multicentre, Randomised Controlled Pragmatic Trial of Mirtazapine to alleviate Breathlessness in Palliative and End of Life... 2023-10-04 bad-data
Other 2019-002106-52 CANnabidiol for Behavioural Symptoms in Alzheimer’s Disease not-yet-due
Other 2019-002661-35 Effect of Iron Isomaltoside on Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Graft ± Valve Surgery: The Ferric Iron in Coronary Artery Bypass Grafting (FERRIC-CABG) Tri... not-yet-due
Other 2019-002880-82 Randomised controlled trial of Gestational treatment with Ursodeoxycholic Acid compared to Metformin to Reduce effects of Diabetes mellitus not-yet-due
Other 2019-003623-37 CANnabidiol for Parkinson’s Disease Psychosis not-yet-due
Other 2020-001056-17 A randomised feasibility trial investigating Sativex® for the treatment of the Agitation & Aggression (A/A) in Alzheimer’s Dementia. not-yet-due
Other 2020-001203-16 Lipid ibuprofen versus standard of care for acute hypoxaemic respiratory failure due to COVID-19: a multicentre, randomised, controlled trial not-yet-due
Other 2020-004917-10 Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative age-Related macular degeneration (TIGER): a phase 3, pan-European, two-group,... not-yet-due
Trial is outside EEC 2021-001279-18 Overall Study Name: NHS CHECK - Health & Experiences of staff working at NHS Trusts and Nightingale Hospitals. Embedded RCT Full Title: Effectiveness of a smartphone app-based intervention in improvi... bad-data