These trials completed more than 12 months ago and should have reported results.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Exempt, with results 2007-007885-39 A Phase 1/2 Study of HKI-272 in Combination with Vinorelbine in Subjects with Solid Tumors and Metastatic Breast Cancer 2018-06-07 not-yet-due
Reported results 2008-005425-11 A Phase 2 Randomized Open Label Study of Neratinib versus Lapatinib plus Capecitabine for the Treatment of ErbB-2 Positive Locally Advanced or Metastatic Breast Cancer 2018-06-20 due-trials
Reported results 2008-007345-31 A Randomized Double-blind Placebo-Controlled Trial of Neratinib (HKI-272) After Trastuzumab in Women With Early-Stage HER-2/neu Overexpressed/Amplified Breast Cancer 2019-10-04 due-trials
Reported results 2008-007803-10 A Phase 3, Randomized, Open-Label, Two-Arm Study of Neratinib Plus Paclitaxel Versus Trastuzumab Plus Paclitaxel as First-Line Treatment for ErbB-2-Positive Locally Recurrent or Metastatic Breast Canc... 2018-06-29 due-trials
Reported results 2012-004492-38 A Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2-Directed Regimens in the Metastatic S... 2019-12-16 due-trials
Reported results 2012-004743-68 A Phase 2 Study of Neratinib and Neratinib Plus Temsirolimus in Patients with Non-Small Cell Lung Cancer Carrying Known HER2 Activating Mutations 2017-10-06 due-trials
Exempt, with results 2012-005037-37 A Phase I/II Trial of Temsirolimus Plus Neratinib for Patients with Metastatic HER2-Amplified or Triple-Negative Breast Cancer 2016-07-04 not-yet-due
Listed as ongoing, but also has a completion date and reported results 2013-002872-42 An Open-Label, Phase 2 Basket Study of Neratinib in Patients With Solid Tumors With Somatic Activation HER Mutations 2023-01-02 bad-data
Reported results 2013-004391-35 A Phase II Randomized Clinical Trial Evaluating Neoadjuvant Therapy Regimens with Weekly Paclitaxel plus Neratinib or Trastuzumab or Neratinib and Trastuzumab Followed by Doxorubicin and Cyclophospham... 2016-11-25 due-trials
Reported results 2015-004374-15 An Open Label Study to Characterize the Incidence and Severity of Diarrhea in Patients with Early Stage HER2+ Breast Cancer Treated with Neratinib and Intensive Loperamide Prophylaxis Estudio abier... 2021-04-22 due-trials
Reported results 2019-001896-35 An Open-Label Phase 2 Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib Estudo aberto de fase 2, para caracterizar a patologia do cólon em d... 2021-12-28 due-trials