These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Ongoing 2006-001202-84 Comparison of the action of amiloride and thiazide in the reduction of lithium-NDI in patients with affective disorders not-yet-due
Ongoing 2006-001574-24 Visualisation of coronary arteries for the analysis of premature atherosclerosis in patients with adult-onset GH deficiency not-yet-due
Completed, but no date, and reported results 2006-002864-24 Drug interactions between ATOvaquone used in MAlaria prophylaxis and antiretroviral agents in HIV-1 infected patients (ATOMA) bad-data
Ongoing 2006-003123-37 Treatment with high dose Methotrexate in patients with eosinophilic fasciitis not-yet-due
Ongoing 2006-003143-23 To study the cardiovasculair effects of vasodilatation by nifedipine (Adalat gastrointestinal therapeutic system) with or without plasma volume expansion with Voluven (colloid) in women with preeclamp... not-yet-due
Ongoing 2006-003981-33 Application of fluorescence diagnosis (FDAP) and photodynamic therapy (PDT) in psoriasis and premalignancies of the skin not-yet-due
Ongoing 2006-004878-28 Does caffeine reduce dipyridamole-induced protection against ischemia-reperfusion injury? not-yet-due
Ongoing 2006-005197-51 Accelerated growth of synchronous colorectal liver metastases: effects of neo-adjuvant therapy not-yet-due
Ongoing 2006-005442-37 PITUITARY DAMAGE AFTER TRAUMATIC BRAIN INJURY; Occurrence of growth hormone deficiency at long term follow-up and the beneficial effects of growth hormone substitution on cardiovascular performance, q... not-yet-due
Ongoing 2006-006181-42 The use of USPIO enhanced MRI in the assessment of axillary lymph node status in patients with invasive breast cancer not-yet-due
Ongoing 2006-006706-29 Does atorvastatin reduce ischemia-reperfusion injury in humans in-vivo? not-yet-due
Ongoing 2006-006776-37 Towards the assessment of metabolic biomarkers and creatine uptake and turnover in skeletal muscles of patients with Facioscapulohumeral muscular dystrophy using MR spectroscopy not-yet-due
Ongoing 2006-007069-35 Evaluation of Neodymium YAG laser-treatment compared to topical treatment with betamethasondipropionaat/calcipotriol ointment (Dovobet) for patients with chronic plaque type psoriasis not-yet-due
Ongoing 2007-000151-33 Does caffeine reduce rosuvastatin-induced protection against ischemia-reperfusion injury? not-yet-due
Completed, but no date Terminated 2007-000210-36 A prospective, randomized, open, multicenter study to evaluate the efficacy and tolerability of induction therapy with a single high-dose anti-T-lymphocyte globulin (ATG-Fresenius) in renal transplant... bad-data
Ongoing 2007-000214-37 Biological and biochemical markers of aneurysm wall degradation; towards non-invasive wall strength analysis. not-yet-due
Ongoing 2007-000310-36 Does statin therapy reduce sympathoexcitation in hypertension not-yet-due
Ongoing 2007-001078-94 Treatment of dumping syndrome with Lanreotide Autogel not-yet-due
Ongoing 2007-001089-33 Infusion of a single dose of erythropoietin to Prevent Injury in an Ischemia Reperfusion forearm model - A randomised cross-over study to evaluate if infusion of a single dose of EPO protects against ... not-yet-due
Completed, but no date 2007-001630-14 Safety and efficacy of efalizumab in combination with methotrexate in patients with severe psoriasis: a comparative study. bad-data
Exempt, with results 2007-002860-86 The adenosine receptor; a new pharmacological tool in the treatment of sepsis. 2008-04-08 not-yet-due
Ongoing, reported early 2007-003347-73 A pharmacokinetic evaluation of the addition of Aprepitant to the Cisplatin - Etoposide (CE) treatment of patients with metastatic lung carcinoma (ACE). not-yet-due
Completed, but no date 2007-003891-20 Een gerandomiseerde placebo gecontroleerde studie naar de toegevoegde waarde van D-cycloserine aan exposure therapie bij patiënten met een poststraumatische stress stoornis bad-data
Ongoing 2007-004620-20 Persantin Preceding PCI not-yet-due
Exempt, with results 2007-005405-21 The influence of Raltegravir (MK_0518) on the pharmacokinetics of single-dose Lamotrigine in healthy male subjects (GRANOLA) 2008-05-10 not-yet-due
Ongoing 2007-005523-15 A phase II study of carboplatin –paclitaxel with bevacizumab followed by the addition of erlotinib to bevacizumab beyond progression in patients with locally advanced and/or metastatic non-small cell ... not-yet-due
Ongoing 2007-005789-11 Does atorvastatin have an acute and prolonged inhibitory effect on ischemia-reperfusion injury in humans in-vivo? not-yet-due
Ongoing 2007-005893-29 Does ATP cause Annexin A5 targeting in the human forearm? not-yet-due
Not reported 2008-000771-17 Hyperbilirubinemia, the favourable side effect of atazanavir? Influence of atazanavir treatment on endothelial dysfunction, vascular inflammation and heme oxygenase activity in type 2 diabetes mellitu... 2009-03-12 due-trials
Ongoing 2008-001282-28 Influenza, pneumococcal and hepatitis B vaccination in patients with rheumatic autoimmune diseases treated with immunosuppressive therapy not-yet-due
Ongoing 2008-001647-19 Treatment with synthetic adrenocoticotropic hormone (ACTH) in patients with membranous nephropathy and high risk for renal failure. A pilot study. not-yet-due
Not reported 2008-001952-32 The effect of adalimumab on immune markers in lesional psoriatic skin. 2010-10-16 due-trials
Ongoing 2008-001972-55 Efficacy of hyperbaric oxygen therapy in the treatment of late radiation damage, osteoradionecrosis, of the lower jaw. not-yet-due
Completed, but no date Terminated 2008-001973-14 TLR ligand matured dendritic cell vaccination in melanoma patients: the key towards a more potent immune induction? bad-data
Completed, but no date, and reported results 2008-001974-33 mRNA-transfected dendritic cell vaccination in high risk uveal melanoma patients bad-data
Ongoing 2008-002672-95 Studie naar de optimale therapieduur van orale angiogenese remmers not-yet-due
Completed, but no date Terminated 2008-004167-19 The effectiveness of antidepressants and psychological intervention in treating conversion disorder, motor type: a randomized placebo controlled clinical trial. bad-data
Reported results 2008-004518-28 Investigation of posaconazole prophylaxis in children with chronic granulomatous disease (CGD): pharmacokinetics and tolerability (iPOD) 2010-06-17 due-trials
Ongoing 2008-005450-20 The cost-effectiveness of abatacept, rituximab or anti-TNF alpha for patients with rheumatoid artritis. not-yet-due
Completed, but no date, and reported results 2008-005584-33 Dendritic cell vaccination in patients with Lynch Syndrome or colorectal cancer with MSI bad-data
Other 2008-006158-16 Investigación sobre la concentración de medicamentos Anti-VIH en la sangre de mujeres embarazadas infectadas por el VIH (Study on Pharmacokinetics of newly developed ANtiretroviral agents in HIV-infec... not-yet-due
Completed, but no date Terminated 2008-006922-32 Heme oxygenase (HO) activity in humans. Effects of heme arginate (Normosang®) on parameters of HO activity and on adenosine induced vasodilation. bad-data
No trial status on register 2008-008246-20 Evaluation of the efficacy and safety of sugammadex (Bridion) in children with renal failure. bad-data
Reported results 2008-008556-16 Pharmacokinetic and safety pilotstudy of RAltegravir and atazanavir in a once DAily dose regimen in HIV-1 in-fected patients (PRADA) 2010-11-22 due-trials
Ongoing 2009-010266-28 Een gerandomiseerde dubbelblinde, placebogecontroleerde, klinische parallelle groep studie van pregabaline in patiënten met chronische pancreatitis not-yet-due
Exempt 2009-010290-21 A phase Ib study of combination of temsirolimus (Torisel®) and pegylated liposomal doxorubicin (PLD, Doxil®/ Caelyx®) in advanced or recurrent breast, endometrial and ovarian cancer not-yet-due
Ongoing 2009-010939-40 PLEASE Persistent Lyme Empiric Antibiotic Study Europe. A prospective, randomised study comparing two prolonged oral antibiotic strategies after initial intravenous ceftriaxone therapy for patients wi... not-yet-due
Ongoing 2009-011906-40 The use of antibiotics in therapy resistant Lichen Sclerosus patientes not-yet-due
Reported results 2009-012073-34 Botulinum toxin for treating calf muscle spasticity in Hereditary Spastic Paraparesis (HSP): functional effects on dynamic balance and gait 2011-05-01 due-trials
Ongoing 2009-012802-38 Evaluation of the activity of temsirolimus with FLT-PET in patients with renal cell cancer not-yet-due
Ongoing 2009-014600-66 A multicentre, prospective, randomized open-label pilot study to assess the feasibility and preliminary efficacy of interferon gamma in combination with Anidulafungin for the treatment of candidemia not-yet-due
Ongoing 2009-014831-18 Short term statin treatment and endothelial dysfunction due to ischemia and reperfusion injury not-yet-due
Ongoing 2009-015099-86 Comparison of efficacy, safety and costs of outpatient biological treatment for psoriasis in daily clinical practice. not-yet-due
Ongoing 2009-015398-11 Pharmacokinetic and pharmacodynamic profile of rapid-acting insulin injected by needle-free jet-injection not-yet-due
Other 2009-015737-73 Single-step antigen loading and TLR activation of dendritic cells by mRNA electroporation for vaccination in stage III and IV melanoma patients not-yet-due
Ongoing 2009-015895-87 Application of zileuton (Zyflo CR) in patients with Sjögren Larsson Syndrome not-yet-due
Ongoing 2009-016053-18 The effect of vildagliptin on endothelium-dependent vasodilatation. A double blind, cross-over study in type 2 diabetes. not-yet-due
Ongoing 2009-016640-39 Everolimus added to long acting octreotide as a volume reducing treatment of polycystic livers. not-yet-due
Ongoing 2009-017849-57 Somatostatin analogues as a volume reducing treatment of polycystic livers not-yet-due
Ongoing 2010-018275-20 A phase II study of cediranib as palliative treatment in patients with symptomatic malignant ascites or pleural effusion not-yet-due
Ongoing 2010-018752-27 Pharmacokinetics of anidulafungin (Ecalta ®) given intravenously as antifungal prophylaxis to recipients of an allogeneic haematopoietic stem cell transplant following myeloablative chemotherapy or pa... not-yet-due
Ongoing 2010-019595-79 A randomised phase II study of radio-chemotherapy with or without panitumumab (Vectibix®) in irresectable squamous cell carcinoma or adenocarcinoma of the oesophagus (Panoramic) not-yet-due
Ongoing 2010-019660-36 The effect of interleukin-1 receptor antagonist on insulin secretion not-yet-due
Ongoing 2010-020228-23 Immunochemotherapy: Do platin-based chemotherapeutics enhance dendritic cell vaccine efficay in melanoma patients? not-yet-due
Listed as ongoing, but also has a completion date and reported results 2010-020371-22 Achieving appropriate exposuRe to RIBAvirin after a dose advise based on an abbreviated AUC of a first dose of ribavirin (ARRIBA) 2014-06-24 bad-data
Ongoing 2010-020875-22 In vivo induction of heme oxygenase-1 (HO-1) in the metabolic syndrome (MetS). Influence of heme arginate (Normosang) infusion on heme oxygenase-1 activity, endothelial dysfunction, insulin resistance... not-yet-due
Ongoing 2010-021166-30 Efficacy and safety of canakinumab in Schnitzler syndrome not-yet-due
Ongoing 2010-021884-34 Relapse prevention in children and adolescents with DSM-IV Conduct Disorder treated with Risperidone: a Randomized Double blind, Placebo-Controlled, Discontinuation Study. not-yet-due
Ongoing 2010-022842-26 Autophagy inhibition using hydrochloroquine in breast cancer patients: a pilot study not-yet-due
Ongoing 2010-023479-24 Effect of Interleukin-1 receptor antagonist on insulin sensitivity in subjects with type 1 diabetes mellitus. not-yet-due
Completed, report not yet due 2010-023757-11 Myeloid and plasmacytoid blood dendritic cells for immunotherapy of stage III melanoma patients scheduled for radical lymph node dissection Myeloide en plasmacytoide dendritische cel vaccinaties vo... 2021-04-14 not-yet-due
Ongoing 2010-024026-38 Combining N-of-1 trials to estimate population clinical effectiveness of drugs using Bayesian hierarchical modeling. The case of Mexilitin for patients with Non-Dystrophic Myotonia. not-yet-due
Not reported 2010-024649-61 Pilot study: performance of the Progensa PCA3 test in post-oxytocin urine specimens 2011-06-10 due-trials
Ongoing 2011-000076-33 Efficacy and Cost Efficacy of Prophylactic treatment with Antibiotics during concomitant chemoradiotherapy in patients with locally advanced head and neck cancer to prevent Aspiration Pneumonia. not-yet-due
Ongoing 2011-000157-23 Street Fitness In surgical patieNts undergoing general anesthesia after reversal of neuromuscular rest blockade with sugammadeX (SFINX study) not-yet-due
Ongoing 2011-000411-12 The effect of Liraglutide on insulin-associated weight gain in patients with type 2 diabetes not-yet-due
Other 2011-000567-26 A randomised double-blind, placebo-controlled study of risperidone in the treatment of DSM-IV-TR conduct disorder in children and adolescents. not-yet-due
Reported results 2011-000643-25 The Qure study: Q-fever fatigue syndrome - response to treatment 2015-09-10 due-trials
Completed, but no date, and reported results 2011-000647-24 The safety, tolerability, and analgesic efficacy of Δ9-THC (Namisol®) in chronic pancreatitis patients suffering from persistent abdominal pain bad-data
Not reported 2011-002222-46 In vivo effects of C1-esterase inhibitor on innate immune response during endotoxemia in human - VECTOR-II study A randomized controlled pilot study 2013-10-31 due-trials
Completed, but no date, and reported results Terminated 2011-005168-14 Lean Body Mass as a determinant of docetaxel pharmacokinetics and toxicity (LEANDOC) bad-data
Ongoing 2011-005289-39 Efficacy and safety of delta-9-tetrahydrocannabinol (delta-THC) in behavioural disturbances and pain in dementia not-yet-due
Not reported 2011-005343-27 Can metformin prevent endothelial ischemia and reperfusion injury? The Metformin-FMD trial. 2013-12-05 due-trials
Ongoing 2011-005970-41 The effect of acetazolamide on lithium-induced nephrogenic diabetes insipidus in patients with an affective disorder: a pilot study Het effect van acetazolamide op lithium-geïnduceerde nefrogene di... not-yet-due
Ongoing 2012-000363-24 The effect of dipyridamole on the pharmacokinetics of metformin. not-yet-due
Ongoing, reported early 2012-000577-22 Palatability testing of a new paediatric formulation of valacyclovir for the prophylaxis and treatment of VZV and HSV infections in children – VALID 0 Smaaktest van een nieuwe kinderformulering van... not-yet-due
Exempt 2012-000619-10 Clinical proof-of-principle of the determination of the beta cell mass in vivo by SPECT imaging with the 111In-labeled GLP-1 analogue DTPA-[K40]-Exendin 4 not-yet-due
Reported results Terminated 2012-000730-19 The analgesic efficacy of Δ9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain: a Randomized, Double-blinded, Placebo-controlled, Parallel Design 2014-09-03 due-trials
Reported results Terminated 2012-000812-27 The analgesic efficacy of Δ9-THC (Namisol®) in patients with persistent postsurgical abdominal pain: a randomized, double-blinded, placebo-controlled, parallel design’ 2014-09-08 due-trials
Ongoing 2012-001809-24 Evaluation of urinary concentrating defects in lithium treated patients with a dDAVP test not-yet-due
Reported results 2012-002222-70 Pilot study: Targeting the inflammatory response after breast cancer surgery with lidocaïne and dexamethasone Pilot onderzoek: Perioperatieve infusie van lidocaïne en dexamethasone voor het vermind... 2016-11-08 due-trials
Reported results Terminated 2012-002491-14 The effects of interferon-gamma on sepsis-induced immunoparalysis, a randomised double-blind placebo-controlled pilot (Phase IIIb) study De effecten van interferon-gamma op sepsis-geïnduceerde immu... 2015-01-01 due-trials
Completed, but no date, and reported results 2012-002531-29 A randomized phase IIa study: natural dendritic cells for immunotherapy of chemo-naive metastatic castration-resistant prostate cancer patients Een gerandomiseerd fase IIa studie: immunotherapie m... bad-data
Exempt 2012-002879-34 Vaccination with minor histocompatibility antigen-loaded donor DC vaccines to boost graft-versus-tumor immunity after allogeneic stem cell transplantation not-yet-due
Ongoing 2012-004560-21 The effect of ticagrelor on the adenosine system Het effect van ticagrelor op het adenosinesysteem not-yet-due
Reported results 2012-004622-14 Concentration/meditation as a novel means to limit inflammation: a randomized controlled pilot study 2011-03-31 due-trials
Ongoing 2012-004819-31 Multicenter open-label RCT to compare colistin alone vs. colistin plus meropenem Trial randomizzato controllato multicentrico per la valutazione dell'efficacia di colistina rispetto a colistina ... not-yet-due
Reported results 2012-004938-42 Experimental Human Rhinovirus Infection, a randomized placebo-controlled pilot study Experimentele menselijke Rhinovirus Infectie, een gerandomiseerde placebo-gecontroleerde pilot studie. 2013-06-28 due-trials
Ongoing, reported early 2012-005372-34 The role of paroxetine in patients taking telaprevir-based HCV therapy: lack of a drug-drug interaction? (ROLEX) not-yet-due
Not reported Terminated 2012-005808-17 The analgesic efficacy of perioperative Δ9-THC (Namisol®) in patients undergoing major abdominal surgery: a randomized, double blinded, placebo-controlled, parallel design 2014-11-17 due-trials
Ongoing 2013-000189-12 Effects of the selective mineralocorticoid receptor antagonist eplerenone on extracellular formation of adenosine De effecten van de selectieve mineralocorticoid receptorantagonist eplerenone op de... not-yet-due
Reported results 2013-001208-12 Switching to aflibercept in patients with neovascular AMD not responding to anti-VEGF treatment. Overstappen op aflibercept in patiënten die niet reageren op anti-VEGF therapie. 2015-05-01 due-trials
Completed, but no date 2013-001554-10 Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: a pilot study Mifepristone en misoprostol versus misoprostol alleen bij de behandeling va... bad-data
Completed, but no date Terminated 2013-001731-40 Influence of exceptional patient characteristics on everolimus exposure De invloed van bijzondere patientkarakteristieken op everolimus blootstelling bad-data
Completed, but no date Terminated 2013-002258-60 prediction of everolimus-induced interstitial lung disease in breast cancer patients; maximizing efficacy by reducing toxicity bad-data
Reported results 2013-002390-21 Effects of oxygen status on endotoxemia induced inflammation and Hypoxia Inducible Factor 1-a. A pilot proof of principle study. 2013-11-26 due-trials
Listed as ongoing, but also has a completion date and reported results 2013-002848-93 Pharmacokinetics of micafungin (Mycamin ®) as antifungal prophylaxis given twice weekly intravenously compared to micafungin given daily to patients at risk for developing an invasive fungal disease. 2016-05-30 bad-data
Ongoing 2013-002886-20 A phase Ib-II study of the combination of cetuximab and methotrexate in recurrent or metastatic squamous cell carcinoma of the head and neck. A study of the Dutch Head and Neck Society. not-yet-due
Completed, but no date 2013-003168-29 A randomized, double-blind, placebo-controlled clinical trial assessing the efficacy of combining pasireotide with aspiration sclerotherapy to improve volume reduction of dominant hepatic cysts bad-data
Completed, but no date, and reported results 2013-003207-19 An international, multicenter, randomized controlled clinical trial assessing the efficacy of Ursodeoxycholic acid as a volume reducing treatment for symptomatic polycystic livers ?Estudio multic... bad-data
Completed, but no date, and reported results 2013-003533-16 Individualizing Pazopanib therapy by exploRing the role of Early metabolic responsE and drug exposure as a preDICTor for treatment outcome in patients with STS Is het vroeg meten van de tumorstofwi... bad-data
Exempt, with results 2013-004108-20 Improving the tolerability of the oral targeted anti-cancer drug pazopanib by food intake (DIET) 2018-08-09 not-yet-due
Ongoing 2013-004174-10 Pharmacokinetics of nitrofurantoin in the elderly not-yet-due
Other 2013-004776-35 Cross-sectional study of 24-hour ambulatory blood pressure measurements and left ventricular mass using echocardiograms in late adolescents and adults with ADHD (ADDUCE protocol WP8 (cardiovascular)) not-yet-due
Completed, but no date 2013-005466-19 Cytokine inhibition in Chronic Fatigue Syndrome patients - a pilot study. Cytokine inhibitie in patiënten met het chronisch vermoeidheidssyndroom. bad-data
Reported results 2013-005520-42 The effects of BCG-vaccination on the innate immune response and immunoparalysis in healthy volunteers 2014-10-31 due-trials
Ongoing 2014-000354-11 The Efficacy of Ibogaine in the Treatment of Addiction; an open label, single fixed dose pilot-study of the efficacy of ibogaine in opioid-dependent subjects not-yet-due
Not reported 2014-000400-99 10-day decitabine, fludarabine and 2 Gray TBI as conditioning strategy for poor and very poor risk AML in CR1 2019-05-07 due-trials
Ongoing 2014-000420-15 Slow continuous subcutaneous flumazenil infusion for benzodiazepine dependence: a pilot study not-yet-due
Reported results 2014-000966-23 The effects of BCG-vaccination on the immune response induced by influenza-vaccination in healthy volunteers A pilot proof-of-principle study De effecten van BCG vaccinatie op de door influenza v... 2014-09-01 due-trials
Exempt, with results 2014-001044-38 Influence of an Acidic Beverage (Coca-Cola) on the exposure to Imatinib (GLIvec) after major gastrecTomY in patients with Gastrointestinal Stromal Tumors (ABILITY) not-yet-due
Completed, but no date, and reported results 2014-001111-39 Once daily DArunavir/ritonavir in HIV-infected children 6-12 years old: a PHarmacokiNEtic validation of model-based dosing recommendations (DAPHNE) bad-data
Ongoing 2014-001777-13 The effect of insulin-induced hypoglycemia on brain lactate accumulation and regional cerebral blood flow in patients with type 1 diabetes mellitus with and without hypoglycemia unawareness and non-di... not-yet-due
Ongoing 2014-003006-33 Effect of Gelofusine on 111In-DTPA-AHX-Lys40-Exendin 4 uptake in the kidney Het effect van Gelofusine op de nieropname van 111In-DTPA-AHX-Lys40-Exendin 4 not-yet-due
Listed as ongoing, but also has a completion date 2014-003080-38 Glutamatergic Medication in the Treatment of Obsessive-Compulsive Disorder (OCD) and Autism Spectrum Disorder (ASD) 2018-09-27 bad-data
Ongoing 2014-003167-38 68Ga-NODAGA-exendin-4 PET/CT in patients with AHH - a prospective comparative evaluation of preoperative imaging Under the FP7 project Betacure (602812); Personalized diagnosis and treatment of hyperi... not-yet-due
Completed, but no date, and reported results 2014-003306-33 Liposomal amphotericin B (Ambisome) pharmacokinetics given as a single intravenous dose to obese patients (ASPEN). bad-data
Ongoing 2014-004032-19 A randomised, open-label clinical trial assessing the efficacy of octreotide to decrease iron infusion and blood transfusion requirements in patients with refractory anaemia due to gastrointestinal bl... not-yet-due
Ongoing 2014-004317-90 Visualizing beta cells in patients with remission of T2DM after bariatric surgery Beeldvorming van beta cellen in patienten met remissie van type 2 diabetes na bariatrische chirurgie not-yet-due
Ongoing 2014-004475-23 Enhancement of exposure therapy for social anxiety disorder with testosterone: A randomized clinical trial De toegevoegde waarde van testosteron bij exposuretherapie voor sociale angststoornis. not-yet-due
Completed, but no date, and reported results Terminated 2014-004488-19 Pharmacokinetics, safety and efficacy of atazanavir /dolutegravir/lamivudine regimen as maintenance regimen in pa-tients with intolerance and/or resistance to NRTIs, NNRTIs and RTV: a pilot study (PRA... bad-data
Ongoing 2014-004513-90 Optimizing abiraterone (Zytiga®) therapy by exploring the relation between an early biomarker - drug exposure - as a predictor for drug response in patients with mCRPC (OPTIMUM - STUDY) not-yet-due
Ongoing 2014-005011-17 Nano MRI on 7 Tesla: A technical validation study in rectal and breast cancer Nano MRI op 7 Tesla: Een eerste validatie study op 7 Tesla in rectum en borst kanker not-yet-due
Ongoing 2014-005537-30 Does ticagrelor modulate the inflammatory respons to human endotoxemia? Heeft ticagrelor een effect op de inflammatoire respons geinduceerd door humane endotoxemie? not-yet-due
Ongoing 2014-005554-20 Visualizing beta cells in patients with postprandial hyperinsulinemic hypoglycemia after bariatric surgery Beeldvorming van beta cellen in patiënten met postprandiale hyperinsulinemische hypoglycae... not-yet-due
Ongoing 2014-005599-27 Visualizing beta cells in morbid obese patients with T2D before and after bariatric surgery (NL51980.091.15) Beeldvorming van beta cellen in morbide obese patienten met T2D voor en na bariatrische ... not-yet-due
Ongoing 2015-000462-62 The effects of statins on skeletal muscle mitochondria: is exercise the medicine? De effecten van statines op skeletspier mitochondria: is inspanning het medicijn? not-yet-due
Exempt Terminated 2015-000821-35 Visualizing beta cells after Intrahepatic Islet of Langerhans Transplantation 2021-05-27 not-yet-due
Ongoing 2015-000860-32 Personalizing enzalutamide (Xtandi®) therapy by understanding the relation between the decrease in the expression profile of a panel of preselected microRNAs, tumor related mRNAs and treatment respons... not-yet-due
Reported results 2015-000943-17 Tight control dose reductions of biologics in psoriasis patients with low disease activity: a randomized pragmatic trial. Dosis reductie van biologics op geleide van ziekteactiviteit in psoriasis p... 2018-07-12 due-trials
Ongoing 2015-002202-37 Pilot study: Is concomitant administration of lidocaine during oxaliplatin infusion able to prevent pain as a result of oxaliplatin induced acute neuropathy? Plot studie: Is het gelijktijdig toedie... not-yet-due
Reported results 2015-002706-36 The effects of different vasopressors on the innate immune response during experimental human endotoxemia, a pilot proof-of-principle study 2016-03-21 due-trials
Reported results 2015-003184-11 Functional effects of botulinum toxin in the hip adductors and subsequent exercise in patients with hereditary spastic paraplegia: a pilot RCT Functionele effecten van botulinetoxine in de heup add... 2017-06-19 due-trials
Ongoing 2015-003698-13 Neuroinflammation in sepsis encephalopathy: the NINEVEH-study not-yet-due
Not reported Terminated 2015-003786-28 Pulmonary NTM disease: A regimen of ethambutol and azithromycin with as adjunctive rifampicin vs clofazimine. Pulmonale infectie met non tuberculeuze mycobacteriën: Een regime bestaande uit ethamb... 2020-07-15 due-trials
Not reported 2015-004023-31 The effects of endotoxin challenge on the immune response elicited by a subsequent challenge with Fluenz™ in healthy volunteers, a pilot study 2016-02-26 due-trials
Ongoing 2015-004613-24 Hit hard and early. The effect of high dose methylprednisolon on nailfold capillary changes and biomarkers in early SSc: a 12-week randomized double-blind placebo-controlled trial. Het effect van h... not-yet-due
Not reported 2015-005016-15 Accuracy of lymph node imaging in prostate cancer: A prospective cohort study to determine the concordance between two imaging modalities, “Combidex” magnetic resonance imaging (Nano MRI) and 68Ga-PSM... 2017-10-30 due-trials
Completed, but no date Terminated 2015-005278-40 Molecular imaging before and during (chemo-) radiotherapy in patients with locally advanced Head and Neck, thoracic and pelvic tumors: prognostic and predictive value of 18F-fluoroazomycin arabinoside... bad-data
Ongoing 2015-005322-19 A randomized, double-blind, placebo-controlled phase III study to evaluate active immunization in adjuvant therapy of patients with stage IIIB and IIIC melanoma with natural dendritic cells pulsed wit... not-yet-due
Completed, but no date, and reported results 2015-005735-40 Safety and protective efficacy of BCG vaccination against controlled human malaria infection bad-data
Not reported Terminated 2016-000367-16 The effect of oxytocin administration on empathy and emotion recognition in healthy and antisocial adolescents 2019-05-20 due-trials
Completed, but no date, and reported results 2016-000790-21 Effect of the GLP-1 receptor agonist exenatide on impaired hypoglycaemic awareness in type 1 diabetes Effect van de GLP-1 receptor agonist exenatide op verminderde hypoglykemie symptoomgewaarwordin... bad-data
Ongoing 2016-000794-20 Visualizing beta cells in patients with a history of gestational diabetes Beeldvorming van beta cellen in patienten met een geschiedenis van zwangerschapsdiabetes not-yet-due
Ongoing, reported early 2016-001182-87 Pharmacokinetics of posaconazole (Noxafil(R)) as prophylaxis for invasive fungal disease not-yet-due
Ongoing 2016-001340-19 An uncontrolled, pilot-study assessing the efficacy of octreotide LAR to decrease transfusion requirements and endoscopy frequency in patients with Rendu-Osler-Weber and gastrointestinal bleeding not-yet-due
Completed, but no date, and reported results Terminated 2016-001379-66 Controlled Human Malaria Infection study to assess gametocytaemia and mosquito transmissibility in participants challenged with Plasmodium falciparum by sporozoite challenge to establish a model for t... bad-data
Completed, but no date, and reported results 2016-001455-42 The influence of metformin and a hypocaloric diet on thyroid radioactive iodide uptake in healthy volunteers: a pilot study De effecten van metformine en een hypocalorische dieet of schildklier jod... bad-data
Completed, but no date, and reported results 2016-001971-61 The effects of acetylsalicylic acid on immunoparalysis following human endotoxemia. Het effect van acetylsalicylzuur op immuunparalyse na humane endotoxemie. bad-data
Ongoing 2016-002016-40 Neuroinflammation in cognitive decline post-cardiac surgery: the FOCUS study not-yet-due
Ongoing 2016-002157-38 Treatment of congenital vascular malformations using Sirolimus: improving quality of Life Behandeling van congenitale vasculaire malformaties met Sirolimus: een studie om de kwaliteit van leven te ... not-yet-due
Reported results 2016-002210-46 Study: Reduces intravenous lidocaine the need for alfentanyl during colonoscopy under Procedural Sedation and Analgesia? 2018-11-17 due-trials
Other 2016-002430-76 Double-blind, randomized, placebo controlled noninferiority intervention study to REduce STEroids in Relapsing Nephrotic syndrome Dubbelblinde, gerandomiseerde, placebo-gecontroleerde non-inferiori... not-yet-due
Ongoing 2016-002588-32 USPIO- enhanced High Field MRI for restaging lymph node status in rectal cancer: an explorative study ultra-hoog veld nano-MRI voor de herstadiering van het lokaal uitgebreid rectumcarcinoom not-yet-due
Ongoing 2016-002602-39 FGF23 response in hypophosphatemia not-yet-due
Ongoing 2016-002784-34 Deferoxamine in Aneurysmal Subarachnoid Hemorrhage pilot trial not-yet-due
Completed, but no date, and reported results 2016-002924-99 The effectiveness of deep versus moderate neuromuscular blockade during laparoscopic donor nephrectomy in enhancing postoperative recovery. Het effect van diepe spierverslapping tijdens laparoscopi... bad-data
Ongoing 2016-003133-18 Preoperative staging by combidex MRI in patients with resectable esophageal carcinoma, a feasibility study Pre-operatieve stadiering met combidex MRI bij patiënten met oesofaguscarcinoom not-yet-due
Ongoing 2016-003144-36 Pilot study: postoperative pain reduction by pre emptive N-Acetylcysteine Pilot studie: postoperatieve pijn reductie door pre emptief N-Acetylcysteine not-yet-due
Ongoing 2016-003279-23 Phase 2 Study testing the COmbination of Vemurafenib With Cobimetinib in BRAF V600 mutated Melanoma Patients to Normalize LDH and Optimize immunotherapY with Nivolumab and Ipilimumab (COWBOY) Fase ... not-yet-due
Ongoing 2016-003321-42 Lengthening Adalimumab Dosing Interval in quiescent Crohn’s disease patients: the LADI study. Adalimumab interval verlenging voor de ziekte van Crohn not-yet-due
Ongoing, reported early 2016-003941-27 Bioequivalence study of CRUshed Sofosbuvir/velpAtasvir compareD to the wholE tablet (CRUSADE-1)/Hep-NED004 not-yet-due
Reported results 2016-004419-11 Safety and efficacy of interleukin-1 inhibitor anakinra for the amelioration of fever during neutropenia and mucositis in patients with multiple myeloma receiving an autologous hematopoietic stem cell... 2020-04-02 due-trials
Completed, but no date 2016-004542-28 A randomized controlled pilot study comparing the efficacy of topical coal tar to topical corticosteroids in children aged 1 to < 16 years with moderate-severe atopic dermatitis. Een gerandomiseer... bad-data
Ongoing 2016-004629-18 The noradrenergic basis of Parkinson’s tremor: a systems-level fMRI approach De noradrenerge basis van Parkinson tremor: een fMRI studie not-yet-due
Completed, but no date 2016-004687-19 A randomized controlled trial evaluating the additional effect of topical coal tar to a topical corticosteroid regimen in patients aged >16 years of age with moderate-severe atopic dermatitis. Een... bad-data
Ongoing 2016-004943-35 Stimulation of ADH independent urine concentration in healthy volunteers not-yet-due
Ongoing 2017-001296-23 The efficacy of botulinum toxin A injection in pelvic floor muscles in chronic pelvic pain patients: a double-blinded randomised controlled trial not-yet-due
Other 2017-001376-28 Multi-center, randomized non-inferiority trial of early treatment versus expectative management of patent ductus arteriosus in preterm infants. Multicenter, gerandomiseerde 'non-inferiority' studie... not-yet-due
Ongoing 2017-001451-30 Pharmacokinetics of a new paediatric formulation of valacyclovir used for prophylaxis and treatment of VZV and HSV infections in children, phase II (VALID II) not-yet-due
Ongoing 2017-002093-40 68Ga-PSMA-PET/CT imaging for locally advanced, recurrent and metastatic adenoid cystic carcinoma or salivary duct carcinoma not-yet-due
Ongoing 2017-002223-25 Pilot study on the effect of prophylactic versus therapeutic treatment with coal tar and vaseline lanette ointment on the skin barrier repair mechanisms in absence of a chronic inflammatory component.... not-yet-due
Reported results Terminated 2017-002694-19 Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: a randomized double blind placebo-controlled comparison (M&M trial). Mifepristone en miso... 2020-01-23 due-trials
Completed, report not yet due Terminated 2017-002739-40 Beta cell imaging in type 1 diabetes with stable near-normal and unstable glucose control using PET Bètacel imaging bij type 1 diabetes met stabiele vrijwel normale en onstabiele glucoseregulatie m... 2021-06-21 not-yet-due
Ongoing 2017-002938-23 The effect of rectal swab culture-guided antimicrobial prophylaxis in men undergoing prostate biopsy on infectious complications and cost of care: A randomized controlled trial in the Netherlands. ... not-yet-due
Ongoing 2017-002959-29 Comparison of the beta cell mass during and shortly after the honeymoon phase of type 1 diabetes using Ga-68-exendin PET Vergelijking van de bètacel-massa tijdens en kort na de honeymoonfase van ty... not-yet-due
Ongoing 2017-003028-59 Treatment with Recombinant human Interleukin 1 receptor antagonist (Anakinra) in patients with Anaplastic Thyroid Cancer: a proof of concept study Behandeling met recombinant humaan Interleukine 1 ... not-yet-due
Ongoing 2017-003270-14 A phase IV, interventional, non-blinded, randomized, controlled, multicenter study of Posaconazole prophylaxis for the prevention of influenza-associated aspergillosis (IAA) in critically ill patients not-yet-due
Ongoing 2017-003366-27 Efficacy of rituximab in comparison to continued corticosteroid treatment in idiopathic nephrotic syndrome unresponsive to 8 weeks of high dose prednisone. not-yet-due
Ongoing 2017-003623-29 MRI measurement of the effects of moderate versus deep neuromuscular blockade on the abdominal working space during laparoscopic surgery in a prospective cohort study. Het effect van standaard vers... not-yet-due
Ongoing, reported early 2017-004005-40 Controlled Human Malaria Infection study to assess gametocytaemia and mosquito transmissibility in participants challenged with Plasmodium falciparum by sporozoite challenge to establish a model for t... not-yet-due
Ongoing 2017-004823-66 Early-life stress, the endocannabinoid system, and fear memory extinction not-yet-due
Ongoing 2018-000046-19 18F-PSMA PET/CT for visualization of glioblastoma multiforme 18F-PSMA PET/CT voor visualisatie van glioblastoma multiforme not-yet-due
Not reported Terminated 2018-000682-36 The efficacy of cabozantinib in advanced salivary gland cancer patients, a phase II clinical trial de effectiviteit van cabozantinib in gevorderd speekselkliercarcinoom, een fase 2 studie 2019-11-05 due-trials
Not reported 2018-000684-82 The effect of lactate administration on cerebral blood flow during hypoglycemia 2019-05-14 due-trials
Ongoing 2018-000779-33 Effect of a reduced dose on cognitive side effects of enzalutamide in frail mCRPC patients not-yet-due
Ongoing 2018-001267-22 F18-PSMA-1007 PET for early biochemical recurrence of prostate cancer, comparison with 18F-Fluciclovine. F18-PSMA-1007 PET voor vroege detectie van een biochemisch recidief van prostaatkanker, verg... not-yet-due
Ongoing 2018-001291-38 Individualized pemetrexed dosing in patients with non-small cell lung cancer or mesothelioma based on renal function to improve treatment response - The IMPROVE-I, -II and -III studies - Dosisindi... not-yet-due
Ongoing 2018-001485-42 RECOVER study: the effect of low- versus normal pressure pneumoperitoneum during laparoscopic colorectal surgery on the early quality of recovery with perioperative care according to the enhanced reco... not-yet-due
Reported results 2018-001569-17 Effect of the SGLT-2 inhibitor dapagliflozin on impaired awareness of hypoglycemia in type 1 diabetes Effect van de SGLT-2 remmer dapagliflozine op verminderde hypoglykemie symptoomgewaarwording (a... 2019-12-20 due-trials
Ongoing 2018-002168-14 Validation of USPIO-enhanced MRI for detection of lymph node metastases in head and neck carcinoma: a pilot study. Validatie van nano-MRI voor detectie van lymfekliermetastasen in hoofd-halskanker:... not-yet-due
Completed, report not yet due 2018-002613-35 Fluconazole pharmacokinetics, including bioavailability, in Obese subjects after an Intravenous and oral Administration (FOLIA). 2021-03-21 not-yet-due
Ongoing 2018-003518-41 Efficacy of Diltiazem to improve coronary microvascular dysfunction: A randomized clinical trial De effectiviteit van Diltiazem om coronaire microvasculaire dysfunctie te verbeteren: een gerandomis... not-yet-due
Ongoing 2018-003566-13 iPAVE – imaging Pituitary ActiVation by Exendin iPAVE - beeldvorming van hypofyse activatie door exendin not-yet-due
Ongoing 2018-004179-11 Effectiveness of Somatostatin Analogues in Patients with hereditary hemorrhagic telangiectasia and symptomatic gastrointestinal bleeding, the SAIPAN-trial: a multicenter, randomized, open-label, paral... not-yet-due
Not reported 2018-004802-24 Optimizing timing of glucocorticoid treatment in children with congenital adrenal hyperplasia Vermijden van over en onderbehandeling door optimalisatie van de timing van cortisol behandeling bij ki... 2020-06-14 due-trials
Ongoing 2018-005046-10 Anakinra: Efficacy of interleukin-1 pathway inhibitor anakinra for the management of fever during neutropenia and mucositis in patients with multiple myeloma receiving an autologous hematopoietic stem... not-yet-due
Ongoing 2019-000670-37 Imaging tumor-infiltrating CD8+ T-cells in non-small cell lung cancer upon neo-adjuvant treatment with Durvalumab (MEDI4736). Afbeelden van tumor-infiltrerende CD8+ T-cellen in niet-kleincellig lon... not-yet-due
Exempt 2019-000938-20 Pharmacokinetic study of minocycline in patients with pulmonary nontuberculous mycobacterial disease Farmacokinetisch onderzoek naar minocycline in patienten met pulmonale nontuberculeuze mycobact... not-yet-due
Ongoing 2019-001843-37 Imaging of tumour microenvironment in patients with oropharyngeal head and neck squamous cell carcinoma using RGD PET/CT imaging. not-yet-due
Ongoing 2019-001869-32 Nano-MRI to visualize pancreatic inflammation in individuals with recent-onset type 1 diabetes not-yet-due
Ongoing 2019-001910-40 Combining emotion recognition training with oxytocin administration: A psychobiological approach not-yet-due
Ongoing 2019-001929-27 Infusion of ex vivo-generated allogeneic natural killer cells in combination with subcutaneous IL-2 in patients with acute myeloid leukemia: a phase I/IIa study’ not-yet-due
Ongoing 2019-002438-35 Multiple doses versus single dose of cefazolin to prevent periprosthetic joint infection after revision arthroplasty: a multicenter open-label, randomized clinical trial. Verlengde profylaxe versu... not-yet-due
Ongoing 2019-002578-29 Functional Improvement of non-infarcT relaTed coronary artery stenosis by Extensive LDL-C Reduction with a PCSK9 Antibody. Functionele verbetering van de niet-infarct gerelateerde coronairarterieve... not-yet-due
Ongoing 2019-002587-28 ABSORB 2:An exploratie study determining the oral antibiotic drug absorption in patients with short bowel syndrome. ABSROB 2: onderzoek naar orale antibiotica opname bij patienten met short bowel s... not-yet-due
Ongoing 2019-003284-21 Radio guided lymph node dissection in oligo metastatic prostate cancer patients; a feasibility study Radioligand gestuurde lymfeklier dissecties bij prostaatkanker patienten met oligo-gemetastaseer... not-yet-due
Ongoing 2019-003857-27 177Lu-PSMA Radioligand Therapy for advanced salivary gland cancer, a phase II pilot study. 177Lu-PSMA radioligand therapie voor gevorderde speekselklierkanker, een fase II pilot study not-yet-due
Ongoing 2019-004222-22 Adjustment of insulin Degludec to Reduce post-Exercise (nocturnal) hypoglycaeMia in people with diabetes – the ADREM study Aanpassing van insuline Degludec om (nachtelijke) hypoglykemie na inspanni... not-yet-due
Ongoing 2019-004230-42 Dose reduction of the new generation biologics (IL17 and IL23 inhibitors) in psoriasis: A pragmatic, multicentre, randomized, controlled, non-inferiority study - BeNeBio study Dosis reductie van de... not-yet-due
Ongoing 2020-000493-15 Dose tapering and Early Discontinuation to InCreAse cosT-effectIveness Of immunotherapy for Non-small cell lung carcinoma trial number 1 not-yet-due
Ongoing 2020-000656-35 The inflammatory response of monocytes and neutrophils to Crystals after Low dose colchicine in patients with coronary artery disease not-yet-due
Ongoing 2020-000712-30 Targeted glucocorticoid administration to improve safety learning in PTSD patients with HPA axis dysregulation Doelgerichte behandeling met glucocorticoïden bij PTSS patiënten met stress-as ontreg... not-yet-due
Ongoing 2020-001240-25 Phase 2 INSPIRE trial: Ipilimumab with Nivolumab in molecular-selected patients with castration-resistant prostate cancer Fase II studie INSPIRE: Ipilimumab met Nivolumab in moleculair geselecteerd... not-yet-due
Completed, report not yet due Terminated 2020-001320-34 A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease Een dubb... 2021-05-25 not-yet-due
Completed, report not yet due 2020-001325-31 [68Ga]Ga-DOTA-(RGD)2 PET/CT imaging of activated endothelium in lung parenchyma of COVID-19 patients. [68Ga]Ga-DOTA-(RGD)2 PET/CT beeldvorming van geactiveerd endotheel in longparenchym van COVID-1... 2021-01-21 not-yet-due
Ongoing 2020-001387-28 18F-PSMA-1007 PET to detect primary prostate cancer: a comparative study with mpMRI and correlation to histopathology. not-yet-due
Ongoing 2020-001591-15 Reducing hospital admission of elderly in SARS-CoV-2 pandemic via the induction of trained immunity by bacillus Calmette-Guérin vaccination, a randomized controlled trial. not-yet-due
Completed, report not yet due 2020-002456-21 Enhancing the BCG-induced trained immunity response by addition of bisphosphonate or MMR vaccine: a possible preventive approach against COVID-19 (BCG-PLUS) 2020-09-03 not-yet-due
Completed, report not yet due 2020-002472-12 Lanadelumab for treatment of COVID-19 disease 2021-02-25 not-yet-due
Ongoing 2020-004075-41 Effectiveness of Somatostatin Analogues in patients with Gastric antral vascular ectasia and symptomatic gastrointestinal bleeding: SAGAVE-Pilot study Effectiviteit van somatostatine-analogen bij p... not-yet-due
Ongoing 2020-004913-11 genotype-guided strategy for antithrombotic treatment versus conventional clopidogrel therapy in peripheral arterial disease’ De toegevoegde waarde van genetisch onderzoek bij het voorschrijven van... not-yet-due
Ongoing 2020-005682-13 Exploratory study into age-related immunological differences related to immunogenicity in influenza vaccination and herpes zoster vaccination Exploratief onderzoek naar leeftijdsgebonden immunolo... not-yet-due
Ongoing 2020-005984-29 [89Zr]Df-IAB22M2C anti-CD8 minibody PET/CT imaging to assess the in vivo distribution of CD8+ T-cells in COVID-19 patients PET/CT beeldvorming met [89Zr]Df-IAB22M2C anti-CD8 minibody voor het beoor... not-yet-due
Ongoing 2021-000182-33 Effect of Bacillus Calmette-Guérin vaccination on the immunogenicity of the mRNA BNT162b2 COVID-19 vaccine in health care workers Effect van Bacillus Calmette-Guérin vaccinatie op de immunogenicite... not-yet-due
Ongoing 2021-001270-34 Enhancement of immune response by combining immune checkpoint blockade and radiation in patients with recurrent / refractory malignant lymphoma (re-directing the immune system). Verbetering van de ... not-yet-due
Ongoing 2021-001509-66 rEaL-world pharmacokinetics of Immune Checkpoint InhibiTors (ELICIT) not-yet-due
Ongoing 2021-001655-13 SARS-CoV2 vaccination and activation of the coagulation system not-yet-due
Ongoing 2021-001817-35 Suboxone (buprenorphine/naloxone) versus methadone opioid rotation in patients with escalated opioid use and chronic pain: a randomized trial. Suboxone (buprenorfine/naloxon) versus methadon opioïd... not-yet-due
Ongoing 2021-002186-17 Timing and sequence of vaccination against COVID-19 and Influenza Timing en volgorde van vaccinatie tegen COVID-19 en Influenza not-yet-due
No trial status on register 2021-004057-23 Ethanol submandibular duct ligation for drooling in children with neurodisabilities bad-data