These trials completed more than 12 months ago and should have reported results. Some have, some have not.

These trials are not yet due to report results: some are ongoing, some completed within the past 12 months.

These trials have problematic data on the registry. Details why »

Status Trial ID Title Completion date Category
Not reported 2004-000629-32 Multicentre international study of capecitabine ± bevacizumab as adjuvant treatment of colorectal cancer 2014-03-31 due-trials
Ongoing, reported early 2004-000658-22 The Second Multi-Centre Intra-Pleural Sepsis Trial (MIST2), to assess whether DNase or Alteplase improves pleural fluid drainage in pleural infection. not-yet-due
Listed as ongoing, but also has a completion date and reported results 2004-001156-37 Study of Heart and Renal Protection 2010-09-02 bad-data
Reported results 2004-001981-41 Bipolar Affective disorder: Lithium/ANti-Convulsant Evaluation 2008-06-30 due-trials
Ongoing, reported early 2004-003341-40 PRE-EMPT: Prevention of Mood Disorders by Folic Acid Supplement. not-yet-due
Ongoing 2004-003836-77 AspECT - A phase III, randomised study of aspirin and esomeprazole chemoprevention in Barrett's metaplasia & oesophagitis. not-yet-due
Ongoing 2004-004290-29 Randomised controlled trial of effect of antibiotic dose on antibiotic resistance in young children with otitis media not-yet-due
Completed, but no date 2004-004684-30 Phase I/II Studie zur Immunisierung mit dem Peptid MAGE-3.A1 gemischt mit der immunologischen Adjuvans CpG 7909 bei Patienten mit metastasiertem Melanom bad-data
Completed, but no date 2004-004686-15 Phase I/II study of immunization with multiple peptides mixed with the immunological adjuvant CpG 7909 in HLA-A2 patients with metastatic melanoma ... bad-data
Ongoing 2004-005118-35 Randomized double-blind phase II trial of NY-ESO-1 ISCOMATRIX and ISCOMATRIXadjuvant alone in patients with resected stage III or IV malignant melanoma not-yet-due
Ongoing 2005-000500-13 Metformin treatment before IVF in women with ultrasound evidence of polycystic ovaries; a prospective, randomised, double blind, placebo controlled study not-yet-due
Ongoing, reported early 2005-001041-42 Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with the virosomal vaccine PEV3A and FP9-MVA ME-TRAP not-yet-due
Reported results 2005-005226-31 TIME 1 The First Therapeutic Intervention in Malignant Pleural Effusion Trial (TIME1) A 2 x 2 randomised factorial trial to assess whether non-steroidal anti-inflammatory analgesics and small bore ch... 2014-04-15 due-trials
Ongoing 2005-005664-88 Prospective Study of Mycobacterium Tuberculosis Specific Cellular immune Responses in Iatrogenically Immunosuppressed Patients: those undergoing TNF-alpha blockade or Awaiting Renal Trasnplants: A Pot... not-yet-due
Ongoing 2005-006141-16 A Randomised, Placebo-Controlled Study of Two Doses of Oral 6R-BH4 on Vascular Function in Subjects with Coronary Artery Disease not-yet-due
Listed as ongoing, but also has a completion date and reported results 2005-006174-97 Which oxygen saturation level should we use for very premature infants? A randomised controlled trial (BOOST-II UK) 2010-12-24 bad-data
Ongoing 2006-000194-29 In Vitro Maturation (IVM) as part of the treatment of infertility in women with polycystic ovaries (PCO). Is priming with hCG favourable? A prospective randomized study. not-yet-due
Ongoing 2006-001317-15 BALANCE 2: Bipolar disorder:Antidepressant/Lamotrigine/ANtipsychotic Comparative Evaluation not-yet-due
Listed as ongoing, but also has a completion date and reported results 2006-001885-17 HPS2-THRIVE (Treatment of HDL to Reduce the Incidence of Vascular Events): A randomized trial of the long-term clinical effects of raising HDL cholesterol with MK 524A (ER niacin and laropipirant). 2012-10-25 bad-data
Reported results 2007-001349-17 A single centre, open-label, randomised clinical trial to investigate Meningococcal serogroup A, C, W-135 and Y saccharide specific B cell response to a primary and a booster dose of the Meningococcal... 2010-10-05 due-trials
Reported results 2007-004360-44 Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with AdCh63 ME-TRAP and MVA ME-TRAP 2008-11-26 due-trials
Ongoing, reported early 2007-004513-33 Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression not-yet-due
Ongoing, reported early 2007-005389-11 A Phase I/IIa Study of the Safety, Immunogenicity and Parasite Growth Inhibitory Activity of AMA1-C1/Alhydrogel® + CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium falciparum Malaria not-yet-due
Ongoing 2007-005391-13 Cancer Oesophagus Gefitinib(COG) - Phase III randomised, double-blind, placebo-controlled trial of gefitinib (Iressa®) versus placebo in oesophageal cancer progressing after chemotherapy. not-yet-due
Ongoing 2008-000281-23 Melatonin in Acute Mania Investigation (MIAMI-UK) not-yet-due
Ongoing, reported early 2008-000586-26 Adjuvant Urokinase in the Treatment of Malignant Pleural Effusion: The Third Therapeutic Intervention in Maligant Effusion Trial (TIME3-UK). A Randomised Controlled Trial to evaluate whether use of in... not-yet-due
Reported results 2008-001024-31 A randomised controlled trial of iodide supplementation in preterm infants with follow-up at 2 years 2015-04-22 due-trials
Reported results 2008-004785-98 An observational study of children immunised in infancy against hepatitis B virus, evaluating the persistence of immunity and the immune response to a scheduled booster dose of hepatitis B vaccine 2011-01-27 due-trials
Ongoing 2008-005759-21 Can atorvastatin improve vascular function in women with a history preeclampsia? A Randomised, double-blinded, placebo-controlled crossover trial of atorvastatin in women with a history of preeclampsi... not-yet-due
Reported results 2008-006302-42 A Phase II study in patients with locally advanced pancreatic carcinoma: ARC-II – Akt-inhibition by Nelfinavir plus chemoradiation with gemcitabine and cisplatin 2015-05-27 due-trials
Ongoing 2008-006486-88 Modafinil for the treatment of fatigue in lung cancer: a multicentre, randomised, double-blinded, placebo-controlled trial not-yet-due
Not reported 2008-006804-46 Assessment of protection against malaria by sporozoite challenge of healthy adults vaccinated with AdCh63 ME-TRAP and MVA ME-TRAP 2011-02-28 due-trials
Ongoing 2008-008553-27 Open-label, randomised multicentre study of CAMPATH-1H versus basiliximab induction treatment and sirolimus versus tacrolimus maintenance treatment for the preservation of renal function in patients r... not-yet-due
Ongoing 2009-009323-11 A randomised controlled trial of natural versus hormone replacement therapy cycles in frozen embryo replacement IVF: a pilot study not-yet-due
Reported results 2009-010334-21 A phase IIa study to assess the safety and efficacy of a new influenza vaccine candidate MVA-NP+M1 in healthy adults. 2010-10-26 due-trials
Reported results 2009-011228-73 A pilot study of Aripiprazole treatment for antipsychotic induced hyperprolactinaemia in young patients with severe mental illness and learning disabilities. 2014-12-31 due-trials
Completed, reported early 2009-012591-27 A phase I/IIa study to assess the safety and immunogenicity of new malaria vaccine candidates AdCh63 MSP1 alone and with MVA MSP1 2010-09-22 not-yet-due
Ongoing 2009-013228-21 Prevention of atrial oxidative stress and electrical remodelling in patients undergoing cardiac surgery: randomised placebo-controlled trial of perioperative high-dose atorvastatin not-yet-due
Listed as ongoing, but also has a completion date and reported results 2009-014469-19 Evaluation of Mirtazapine and Folic Acid for Schizophrenia: A Large Simple 2x2 Factorial Trial. 2013-10-19 bad-data
Reported results 2009-014719-11 Open Label, Randomized, Parallel-Group, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Baxter H1N1 vaccine and GlaxoSmithKline H1N1 vaccine in children 6 months to 12 ye... 2011-05-24 due-trials
Ongoing, reported early 2009-016459-23 Single arm NCRI feasibility study of CHOP in combination with Ofatumumab in induction and maintenance for patients with newly diagnosed Richter’s Syndrome not-yet-due
Ongoing 2009-016579-31 An open label randomised controlled study to evaluate the induction of immune memory following infant vaccination with a glyco-conjugate Neisseria meningitidis serogroup C vaccine and to assess the im... not-yet-due
Ongoing, reported early 2009-016846-16 Phase II Clinical Trial of 6-Mercaptopurine(6MP)and low-dose Methotrexate In Patients With Known BRCA Defective Tumours. not-yet-due
Ongoing, reported early 2009-017498-39 A follow-on, multi-centre, open-label, clinical, phase 3 trial to investigate the persistence of serotype-specific antibodies at 40 months of age in children who have received either the 7-valent or t... not-yet-due
Listed as ongoing, but also has a completion date 2009-017885-22 Phase II Study of ADI-PEG 20 in Patients with Relapsed Sensitive or Refractory Small Cell Lung Cancer 2013-06-24 bad-data
Ongoing 2009-018153-23 A double blind randomised phase 2 trial of docetaxel with or without AZD6244 in wt BRAF advanced melanoma not-yet-due
Reported results 2010-018341-56 A phase I/IIa sporozoite challenge study to assess the safety, immunogenicity and protective efficacy of new malaria vaccine candidates; AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & ... 2011-03-15 due-trials
Reported results 2010-019091-78 An observational study into the maintenance of seroprotection against Meningococcal serogroup C disease throughout childhood following a single dose of a conjugated Meningococcal serogroup C vaccine a... 2011-05-16 due-trials
Reported results 2010-019647-19 A double blind randomised placebo controlled trial of montelukast in the treatment of acute persistent cough in young people and adults (aged 16-49) in primary care 2012-10-23 due-trials
Reported results 2010-020621-40 SONATINA: A Phase II Multi-Centre Randomised Controlled Study of Nelfinavir Addition to Radiotherapy Treatment in Neo-Adjuvant Therapy for Rectal Cancer 2014-01-07 due-trials
Ongoing 2010-022589-29 Investigation of pathways regulating cell survival and early antiangiogenic response to single agent Everolimus or Rapamycin in renal cancer not-yet-due
Not reported 2010-022817-24 A multi-centre, open-label, clinical, phase 4 trial, following on from a head-to-head comparison study of two H1N1 influenza vaccines in children, to compare firstly, the persistence of antibody again... 2011-08-05 due-trials
Ongoing 2010-023467-18 HPS 3 / TIMI 55: REVEAL (Randomized EValuation of the Effects of Anacetrapib through Lipid-modification): A large-scale, randomized placebo-controlled trial of the clinical effects of anacetrapib amo... not-yet-due
Ongoing 2011-000381-35 Understanding typhoid disease after vaccination: a single centre, randomised, double-blind, placebo-controlled study to evaluate M01ZH09 in a healthy adult challenge model, using Ty21a vaccine as a po... not-yet-due
Reported results 2011-000661-12 A randomised double blind phase 2 trial of whole brain radiotherapy with or without vandetanib in metastatic melanoma with brain metastases 2014-11-28 due-trials
Ongoing 2011-002038-37 Hyperpolarised xenon magnetic resonance imaging (Xe-129 MRI) lung imaging in COPD not-yet-due
Ongoing, reported early 2011-002545-35 A randomised phase 2 study of paclitaxel with or without GSK1120212 in advanced wt BRAF melanoma not-yet-due
Not reported 2011-003123-35 The impact of single versus double dose acetylsalicylic acid on platelet function in patients with type 2 diabetes (the "ASP Study"). 2013-01-18 due-trials
Ongoing 2011-003311-27 Vascular Targeted Photodynamic therapy with WST11 for T1a Renal Tumours. PHASE IIa histological follow up trial not-yet-due
Ongoing 2011-005102-30 A phase III randomised, open label clinical trial evaluating the immunogenicity of a 10-valent pneumococcal conjugate vaccine booster compared to the standard 13-valent pneumococcal conjugate vaccine ... not-yet-due
Reported results 2011-005477-24 A Phase I/IIa Sporozoite Challenge Study to Assess the Protective Efficacy of Two Prime-boost Malaria Vaccine Candidates: ChAd63 and MVA encoding ME-TRAP and the same Viral Vectors encoding CS 2012-11-07 due-trials
Ongoing, reported early 2011-005763-24 BEST-D (Biochemical efficacy and safety trial of vitamin D): a dose-finding trial assessing biochemical and vascular effects of high dose vitamin D not-yet-due
Reported results 2012-000147-27 A Single-Blind Randomised Controlled Pilot trial of Corticosteroid Injection for Shoulder Pain 2013-03-31 due-trials
Listed as ongoing, but also has a completion date and reported results 2012-000615-84 A Mechanistic Study Of Mifamurtide (MTP-PE) In Patients With Metastatic And/Or Recurrent Osteosarcoma 2016-11-04 bad-data
Ongoing, reported early 2012-000616-28 Phase II trial of Linsitinib (anti-IGFR/IR) in patients with relapsed and/or refractory Ewing Sarcoma not-yet-due
Ongoing, reported early 2012-002443-26 A phase II, multi-centre, open labelled randomised control trial to describe immune & transcriptomic responses to trivalent inactivated vaccine (TIV) & MF59 adjuvanted influenza vaccine (ATIV) in 14 -... not-yet-due
Ongoing 2012-002672-13 Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) Trial: a prospective randomised open blinded endpoint trial to determine the effect of aldosterone receptor antagonism ... not-yet-due
Ongoing 2012-002952-17 Effects of intravenous iron on hypoxic pulmonary responses in COPD not-yet-due
Ongoing 2012-003191-39 The effect of a single-dose of d-cycloserine on the basic effects of cognitive-behaviour therapy for panic disorder - a randomized placebo-controlled trial not-yet-due
Ongoing 2012-004260-22 A multi-centre randomised placebo-controlled trial of prophylactic enteral lactoferrin supplementation to prevent late-onset invasive infection in very preterm infants. not-yet-due
Reported results 2012-004330-41 Do oral corticosteroids provide clinical and cost-effective symptom relief for sore throat? A multi-centre, double blind, randomized, placebo-controlled trial. 2015-04-16 due-trials
Reported results 2012-004416-66 A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches using the ChAd63 and MVA vectors encoding the antigens ME-TRAP, CS and AMA1. 2013-10-14 due-trials
Not reported 2012-004954-27 A single centre open-label randomised controlled trial of long term pituitary down-regulation before in vitro fertilisation for women with endometriosis: a pilot study 2013-11-07 due-trials
Reported results 2013-000393-30 A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of the Combination Malaria Vaccine Candidate Regimen of RTS,S/AS01B + ChAd63 and MVA encoding ME-TRAP and also RTS... 2014-08-21 due-trials
Ongoing 2013-001024-19 An open label single-arm study of the immunogenicity and reactogenicity of a 13-valent pneumococcal conjugate vaccine (Prevenar13®) given to children with type 1 diabetes mellitus who have not previou... not-yet-due
Ongoing, reported early 2013-002259-14 The effect of lixisenatide in type 1 diabetes not-yet-due
Ongoing 2013-002822-21 The early use of Antibiotics for at Risk CHildren with InfluEnza in primary care (ARCHIE): a double-blind randomised placebo-controlled trial not-yet-due
Ongoing 2013-003488-71 A pilot study of the impact of BCG administration on the immunogenicity of serogroup C meningococcal conjugate vaccine in healthy infants not-yet-due
Ongoing 2013-004968-56 A multi-centre randomised study of induction chemotherapy followed by capecitabine (+/-nelfinavir) with high or standard dose radiotherapy for locally advanced non-metastatic pancreatic cancer not-yet-due
No trial status on register 2013-005336-23 Outcome After Selective Early Treatment for Closure of Patent Ductus Arteriosus in Pre-term Babies bad-data
Ongoing 2014-000126-38 Towards improved meningococcal vaccines: a randomised, descriptive, open label study exploring the relationship between gene expression signatures with reactogenicity and immunogenicity following vacc... not-yet-due
Other 2014-000463-40 A Sequential Phase I study of MEK1/2 inhibitors PD-0325901 or Binimetinib combined with cMET inhibitor Crizotinib in RAS Mutant and RAS Wild Type(with aberrant c-MET) Colorectal Cancer not-yet-due
Reported results 2014-001301-40 A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of Concomitant Administration of the Combination Malaria Vaccine Candidate Regimen of RTS,S/AS01¬B + ChAd63 and MV... 2015-10-16 due-trials
Ongoing 2014-002699-98 OxLith: Exploration of the short-term physical and psychological effects of lithium in mood instability not-yet-due
Ongoing 2014-002978-36 Vaccines Against Salmonella Typhi: a phase IIb, single centre, observer-blind, randomised controlled trial to assess the immunogenicity and protective efficacy of Vi conjugated (Vi-TCV) and unconjugat... not-yet-due
Ongoing 2014-002997-35 A phase III multi-centre randomised, double blind, placebo controlled trial to assess the role of intravenous immunoglobulin in the management of children with encephalitis (The IgNiTE study) not-yet-due
Other 2014-003237-25 A blinded randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants not-yet-due
Listed as ongoing, but also has a completion date 2014-004471-23 Antivirals for influenza Like Illness? An rCt of Clinical and Cost effectiveness in primary CarE 2018-05-09 bad-data
Ongoing 2015-000817-32 Assessment of post booster antibody responses in UK infants given a reduced priming schedule of meningococcal serogroup B and 13 valent pneumococcal conjugate vaccines not-yet-due
Ongoing 2015-000872-89 ANODE: a randomised controlled trial of prophylactic ANtibiotics to investigate the prevention of infection following Operative vaginal DElivery. not-yet-due
Ongoing 2015-001321-17 A randomised control trial of 5-Aminolevulinic Acid in combination with Sodium Ferrous Citrate to Enhance Cardioprotection in Adults undergoing Cardiac Surgery not-yet-due
Ongoing 2015-001383-18 An open label Phase 2 clinical trial of retinal gene therapy for choroideremia using an adeno-associated viral vector (AAV2) encoding Rab-escort protein 1 (REP1) not-yet-due
Ongoing 2015-001780-40 A multi-centre, double blind, randomised, placebo-controlled, parallel group, phase II trial to determine the efficacy of intra-nodular injection of anti-TNF to control disease progression in early Du... not-yet-due
Ongoing 2015-002837-23 Low-dose Glibenclamide in Type 2 Diabetes Mellitus - Part A (LEGEND-A) not-yet-due
Ongoing 2015-003542-68 The effect of single-dose losartan on the basic effects of cognitive-behaviour therapy for panic disorder - a randomized double blind placebo-controlled trial not-yet-due
Ongoing 2015-005298-19 Phase 1/2 Study of anti-PD-L1 in Combination with Chemo(radio)therapy for Oesophageal Cancer not-yet-due
Ongoing 2016-000559-28 Randomised phase II Trial of olaparib, chemotherapy or olaparib and cediranib in patients with BRCA mutated platinum–resistant ovarian cancer not-yet-due
Ongoing 2016-001265-92 A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of adjuvanted R21 at different doses and the Combination Malaria Vaccine Candidate Regimen of adjuvanted R21 + ChA... not-yet-due
Ongoing 2016-001718-31 A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium falciparum malaria vaccine candidate RH5.1/AS01 not-yet-due
Ongoing 2016-002267-33 A parallel group phase I/II marker lesion study to assess the safety, tolerability and efficacy of intravenous or intravesical pembrolizumab in intermediate risk recurrent non-muscle invasive bladder ... not-yet-due
Ongoing 2016-002656-24 A randomised placebo-controlled clinical trial of fenofibrate to prevent progression of non-proliferative retinopathy in diabetes not-yet-due
Ongoing 2016-002991-28 GRASP: Getting it Right: Addressing Shoulder Pain. Clinical and cost effectiveness of progressive exercise compared to best practice advice, with or without corticosteroid injection, for the treatmen... not-yet-due
Ongoing 2016-003060-40 Targeting Iatrogenic Cushing’s Syndrome with 11β-hydroxysteroid dehydrogenase type 1 Inhibition not-yet-due
Ongoing 2016-003109-32 An investigation of Levetiracetam in Alzheimer’s Disease (ILiAD): a proof of concept study not-yet-due
Ongoing 2016-003678-42 Immunological effects of an acellular pertussis booster vaccination in children, young adults and elderly with different immunisation background. An international study in Finland, the Netherlands and... not-yet-due
Ongoing 2016-004236-38 OPtimising Treatment for MIld Systolic hypertension in the Elderly: a randomised controlled trial not-yet-due
Ongoing 2017-000124-95 Randomised Controlled Crossover Trial of Inhaled Furosemide for Dyspnoea Relief in Advanced Heart Failure not-yet-due
Ongoing 2017-001421-41 The TWO Study: Transplantation Without Over-immunosuppression. A Phase IIb Trial of Regulatory T Cells in Renal Transplantation. not-yet-due
Ongoing 2017-002798-21 A multi-centre, blinded, randomised, placebo-controlled trial assessing the clinical and cost effectiveness of a 12 month course of oral alendronate (70mg weekly) in patients presenting with avascular... not-yet-due
Ongoing 2017-004542-24 Clinical effectiveness of standard step up care (methotrexate) compared to early combination DMARD therapy with standard step up care compared to early use of TNF inhibitors with standard step up care... not-yet-due